JPWO2018091937A5 - - Google Patents

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Publication number
JPWO2018091937A5
JPWO2018091937A5 JP2019547794A JP2019547794A JPWO2018091937A5 JP WO2018091937 A5 JPWO2018091937 A5 JP WO2018091937A5 JP 2019547794 A JP2019547794 A JP 2019547794A JP 2019547794 A JP2019547794 A JP 2019547794A JP WO2018091937 A5 JPWO2018091937 A5 JP WO2018091937A5
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JP
Japan
Prior art keywords
compound
cis
pharmaceutical
nutraceutical composition
alkyl
Prior art date
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Application number
JP2019547794A
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English (en)
Japanese (ja)
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JP7266247B2 (ja
JP2020513417A (ja
JP7266247B6 (ja
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Priority claimed from PCT/HU2017/050047 external-priority patent/WO2018091937A1/en
Publication of JP2020513417A publication Critical patent/JP2020513417A/ja
Publication of JPWO2018091937A5 publication Critical patent/JPWO2018091937A5/ja
Publication of JP7266247B2 publication Critical patent/JP7266247B2/ja
Application granted granted Critical
Publication of JP7266247B6 publication Critical patent/JP7266247B6/ja
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JP2019547794A 2016-11-17 2017-11-17 ビタミンa5経路のレチノイド類を提供するための前駆体化合物及びその使用 Active JP7266247B6 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
HUP1600629 2016-11-17
HUP1600629 2016-11-17
HUP1700196 2017-05-05
HUP1700196 2017-05-05
PCT/HU2017/050047 WO2018091937A1 (en) 2016-11-17 2017-11-17 Precursor compounds for providing retinoids of the vitamin a5 pathway and uses thereof

Publications (4)

Publication Number Publication Date
JP2020513417A JP2020513417A (ja) 2020-05-14
JPWO2018091937A5 true JPWO2018091937A5 (enExample) 2022-12-27
JP7266247B2 JP7266247B2 (ja) 2023-04-28
JP7266247B6 JP7266247B6 (ja) 2024-02-15

Family

ID=89720182

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019547794A Active JP7266247B6 (ja) 2016-11-17 2017-11-17 ビタミンa5経路のレチノイド類を提供するための前駆体化合物及びその使用

Country Status (9)

Country Link
EP (1) EP3541783B1 (enExample)
JP (1) JP7266247B6 (enExample)
CN (2) CN116268424B (enExample)
AU (1) AU2017359593B2 (enExample)
CA (1) CA3082441A1 (enExample)
ES (1) ES2967076T3 (enExample)
HU (1) HUE064808T2 (enExample)
PL (1) PL3541783T3 (enExample)
WO (1) WO2018091937A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021038637A1 (ja) * 2019-08-23 2021-03-04 リファインホールディングス株式会社 新規ビタミンa誘導体およびその製造方法
WO2021197890A1 (en) * 2020-03-31 2021-10-07 Dsm Ip Assets B.V. Process for production of vitamin a
US20230338305A1 (en) * 2020-05-06 2023-10-26 Regenall Limited Vitamin a for use in the treatment of traumatic brain injury
CN112522331B (zh) * 2020-12-09 2024-03-22 上海克琴科技有限公司 一种生物酶催化的羟基频哪酮视黄酸酯的合成方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62248495A (ja) 1986-04-23 1987-10-29 Mihama Hisaharu ビタミンaエステルの製法
US5310554A (en) * 1992-10-27 1994-05-10 Natural Carotene Corporation High purity beta-carotene
CA2164291C (en) 1993-06-09 2007-10-30 David John Kyle Methods and pharmaceutical compositions useful for treating neurological disorders
US5508456A (en) 1993-07-30 1996-04-16 Ligand Pharmaceuticals Incorporated 9-cis tritium-labeled retinoids and intermediates, methods for their synthesis and methods for their use in discovering retinoid X receptor ligands
WO1995032946A1 (en) 1994-05-27 1995-12-07 Ligand Pharmaceuticals Incorporated Methods for the synthesis of 9-cis retinoids and their novel intermediates
GB0103998D0 (en) * 2001-02-19 2001-04-04 King S College London Method
US20070148106A1 (en) * 2005-06-15 2007-06-28 Karin Wertz Treatment, prevention, and modulation of aging of the skin
EP1962618A2 (en) * 2005-12-20 2008-09-03 Alcon Research, Ltd. Composition and methods for inhibiting the progression macular degeneration and promoting healthy vision
US20110082218A1 (en) * 2006-06-15 2011-04-07 Karin Wertz Treatment and modulation of gene expression and skin aging
US7566795B2 (en) 2006-10-06 2009-07-28 Eastman Chemical Company Preparation of retinyl esters
CA2774168C (en) 2009-09-15 2021-02-23 Ronald Erwin Boch Pharmaceutical formulations comprising 9-cis-retinyl esters in a lipid vehicle
DK2819667T3 (da) 2012-03-01 2020-03-30 Retinagenix Therapeutics Inc Retinalderivater til anvendelse til forbedring af synsfunktionen
WO2016076454A1 (ko) * 2014-11-10 2016-05-19 한국생명공학연구원 미생물의 배양방법 및 그 배양미생물로부터 9-시스 베타카로틴의 분리 및 정제방법
US20180170867A1 (en) * 2015-05-08 2018-06-21 University Of Debrecen Stereoselective synthesis of 9-cis.13,14-dihydroretinoic acid and its ethyl esters

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