JPS6490149A - Pharmacological ethers and thioethers, manufacture and drug composition - Google Patents

Pharmacological ethers and thioethers, manufacture and drug composition

Info

Publication number
JPS6490149A
JPS6490149A JP63201782A JP20178288A JPS6490149A JP S6490149 A JPS6490149 A JP S6490149A JP 63201782 A JP63201782 A JP 63201782A JP 20178288 A JP20178288 A JP 20178288A JP S6490149 A JPS6490149 A JP S6490149A
Authority
JP
Japan
Prior art keywords
thioethers
pharmacological
ethers
manufacture
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP63201782A
Other languages
English (en)
Inventor
Supinetsuri Shirubano
Dei Domeniko Roberuto
Menta Erunesuto
Rumaki Buruno
Gatsuriko Richia
Tonetsura Serujio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Italia SpA
Original Assignee
Boehringer Biochemia Robin SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Biochemia Robin SpA filed Critical Boehringer Biochemia Robin SpA
Publication of JPS6490149A publication Critical patent/JPS6490149A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP63201782A 1987-08-14 1988-08-12 Pharmacological ethers and thioethers, manufacture and drug composition Pending JPS6490149A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21657/87A IT1222500B (it) 1987-08-14 1987-08-14 Eteri e tioteri ad attivita' terapeutica,loro preparazione e composizioni che li contengono

Publications (1)

Publication Number Publication Date
JPS6490149A true JPS6490149A (en) 1989-04-06

Family

ID=11184932

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63201782A Pending JPS6490149A (en) 1987-08-14 1988-08-12 Pharmacological ethers and thioethers, manufacture and drug composition

Country Status (15)

Country Link
US (1) US4968706A (ja)
EP (1) EP0303227B1 (ja)
JP (1) JPS6490149A (ja)
AT (1) ATE72433T1 (ja)
CA (1) CA1326668C (ja)
DD (1) DD277069A5 (ja)
DE (1) DE3868302D1 (ja)
DK (1) DK449788A (ja)
ES (1) ES2034062T3 (ja)
FI (1) FI883730A (ja)
HU (1) HU201749B (ja)
IT (1) IT1222500B (ja)
NZ (1) NZ225800A (ja)
PT (1) PT88242B (ja)
ZA (1) ZA885932B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005306755A (ja) * 2004-04-19 2005-11-04 Daicel Chem Ind Ltd ２−ベンゾイルオキシアセトアルデヒド誘導体の製造法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268007A (en) * 1986-12-29 1993-12-07 The Lubrizol Corporation Dioxolanes and thio analogs, derivatives thereof and lubricants and fuels containing same
DE102012003286A1 (de) * 2012-02-20 2013-08-22 Merz Pharma Gmbh & Co. Kgaa Kombination aus Lipidtransferproteinen und Phenolderivate enthaltenden Pflanzenstoffen mit lokal-mucosaler Effizienz

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097581A (en) * 1975-12-12 1978-06-27 Ciba-Geigy Corporation Dioxolane derivatives
GB8314521D0 (en) * 1983-05-25 1983-06-29 Pickett J A Behaviour modifying compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005306755A (ja) * 2004-04-19 2005-11-04 Daicel Chem Ind Ltd ２−ベンゾイルオキシアセトアルデヒド誘導体の製造法

Also Published As

Publication number Publication date
DK449788A (da) 1989-02-15
FI883730A (fi) 1989-02-15
IT1222500B (it) 1990-09-05
ZA885932B (en) 1989-04-26
US4968706A (en) 1990-11-06
NZ225800A (en) 1990-07-26
ES2034062T3 (es) 1993-04-01
ATE72433T1 (de) 1992-02-15
EP0303227B1 (en) 1992-02-05
DK449788D0 (da) 1988-08-11
CA1326668C (en) 1994-02-01
AU2067288A (en) 1989-02-16
DD277069A5 (de) 1990-03-21
HUT49110A (en) 1989-08-28
FI883730A0 (fi) 1988-08-11
EP0303227A1 (en) 1989-02-15
IT8721657A0 (it) 1987-08-14
PT88242A (pt) 1989-06-30
HU201749B (en) 1990-12-28
AU613656B2 (en) 1991-08-08
DE3868302D1 (de) 1992-03-19
PT88242B (pt) 1995-03-01

Similar Documents

Publication Publication Date Title
ES8705886A1 (es) Un metodo para preparar un derivadode tiazolidin-diona
EP0262399A3 (en) Cyclic enol derivatives, production and use thereof
ES8707947A1 (es) Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos.
HUT45984A (en) Process for production of quinoline-derivatives and of their medically acceptable acid-additioned salts
AU2868689A (en) Use of 1,4-disubstituted-piperidinyl compounds in the manufacture of a medicament for the treatment of insomnia
PT80191B (en) Process for preparing substituted benzopyrans useful as medicaments
JPS6490149A (en) Pharmacological ethers and thioethers, manufacture and drug composition
ES8802508A1 (es) Procedimiento para preparar derivados alquenicos.
HUT49340A (en) Process for production of derivatives of tioformamid and medical compositions containing them
ES8802509A1 (es) Procedimiento para preparar derivados de 1,3-oxatiano
ES8500955A1 (es) Procedimiento para la preparacion de furobenzoisoxazoles.
IE880306L (en) Pyridopyrroloquinolines and intermediates thereof
ES8801270A1 (es) Un procedimiento para preparar benzo (c)-1,5-naftiridinas
EP0449011A3 (en) Stereoselective process for the preparation of 2-amino-ethanol derivatives having a central analgesic activity and intermediates thereof
FI894125A0 (fi) Analogiamenetelmä terapeuttisesti käyttökelpoisen 3-piperidinyyli-indatsolin valmistamiseksi
JPS55147279A (en) Preparation of 2,3-dipyridylquinazolinone derivative
AU2013888A (en) Uricosuric composition
ES479005A1 (es) Un procedimiento para obtener derivados de quinazolina.
ES8506700A1 (es) Un procedimiento para preparar nuevas 5-aminometil-imidazol-1-il-1,3-dialquil-1h-pirazol-4-il-aroil-metanonas