IT1222500B - Eteri e tioteri ad attivita' terapeutica,loro preparazione e composizioni che li contengono - Google Patents

Eteri e tioteri ad attivita' terapeutica,loro preparazione e composizioni che li contengono

Info

Publication number
IT1222500B
IT1222500B IT21657/87A IT2165787A IT1222500B IT 1222500 B IT1222500 B IT 1222500B IT 21657/87 A IT21657/87 A IT 21657/87A IT 2165787 A IT2165787 A IT 2165787A IT 1222500 B IT1222500 B IT 1222500B
Authority
IT
Italy
Prior art keywords
group
tioteri
ethers
therapeutic
preparation
Prior art date
Application number
IT21657/87A
Other languages
English (en)
Other versions
IT8721657A0 (it
Inventor
Silvano Spinelli
Domenico Roberto Di
Ernesto Menta
Bruno Lumachi
Lici Gallico
Sergio Tognella
Original Assignee
Boeringer Biochimica Robin S P
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boeringer Biochimica Robin S P filed Critical Boeringer Biochimica Robin S P
Publication of IT8721657A0 publication Critical patent/IT8721657A0/it
Priority to IT21657/87A priority Critical patent/IT1222500B/it
Priority to AT88112922T priority patent/ATE72433T1/de
Priority to DE8888112922T priority patent/DE3868302D1/de
Priority to EP88112922A priority patent/EP0303227B1/en
Priority to ES198888112922T priority patent/ES2034062T3/es
Priority to HU884315A priority patent/HU201749B/hu
Priority to FI883730A priority patent/FI883730A/fi
Priority to CA000574445A priority patent/CA1326668C/en
Priority to ZA885932A priority patent/ZA885932B/xx
Priority to US07/230,821 priority patent/US4968706A/en
Priority to PT88242A priority patent/PT88242B/pt
Priority to NZ225800A priority patent/NZ225800A/xx
Priority to DK449788A priority patent/DK449788A/da
Priority to JP63201782A priority patent/JPS6490149A/ja
Priority to DD88318906A priority patent/DD277069A5/de
Priority to AU20672/88A priority patent/AU613656C/en
Priority to US07/559,036 priority patent/US5212316A/en
Application granted granted Critical
Publication of IT1222500B publication Critical patent/IT1222500B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IT21657/87A 1987-08-14 1987-08-14 Eteri e tioteri ad attivita' terapeutica,loro preparazione e composizioni che li contengono IT1222500B (it)

Priority Applications (17)

Application Number Priority Date Filing Date Title
IT21657/87A IT1222500B (it) 1987-08-14 1987-08-14 Eteri e tioteri ad attivita' terapeutica,loro preparazione e composizioni che li contengono
AT88112922T ATE72433T1 (de) 1987-08-14 1988-08-09 Aether und thioaether mit heilender wirkung, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.
DE8888112922T DE3868302D1 (de) 1987-08-14 1988-08-09 Aether und thioaether mit heilender wirkung, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.
EP88112922A EP0303227B1 (en) 1987-08-14 1988-08-09 Ethers and thioethers having therapeutical activity, their preparation and pharmaceutical compositions containing them
ES198888112922T ES2034062T3 (es) 1987-08-14 1988-08-09 Eteres y tioeteres que tienen actividad terapeutica, su preparacion y composiciones farmaceuticas que los contienen.
ZA885932A ZA885932B (en) 1987-08-14 1988-08-11 Ethers and thioethers having therapeutical activity,their preparation and pharmaceutical compositions containing them
DK449788A DK449788A (da) 1987-08-14 1988-08-11 Ethere og thioethere med terapeutisk virkning, deres fremstilling og farmaceutiske midler indeholdende dem
CA000574445A CA1326668C (en) 1987-08-14 1988-08-11 Ethers and thioethers having therapeutical activity, their preparation and pharmaceutical compositions containing them
HU884315A HU201749B (en) 1987-08-14 1988-08-11 Process for producing ether and thioether derivatives and pharmaceutical compositions comprising such compounds as active ingredient
US07/230,821 US4968706A (en) 1987-08-14 1988-08-11 Ethers and thioethers having therapeutical activity, their preparation and pharmaceutical compositions containing them
PT88242A PT88242B (pt) 1987-08-14 1988-08-11 Processo para a preparacao de eteres e tioeteres tendo actividade terapeutica
NZ225800A NZ225800A (en) 1987-08-14 1988-08-11 Optionally heterocyclically-substituted ethers and thio ethers and pharmaceutical compositions
FI883730A FI883730A (fi) 1987-08-14 1988-08-11 Etrar och tioetrar med terapeutisk effekt, framstaellning av dessa och farmaceutiska sammansaettningar som innehaoller dem.
JP63201782A JPS6490149A (en) 1987-08-14 1988-08-12 Pharmacological ethers and thioethers, manufacture and drug composition
DD88318906A DD277069A5 (de) 1987-08-14 1988-08-12 Ether und thioether mit therapeutischer wirkung, ihrer herstellung und pharmazeutische verbindungen, die sie enthalten
AU20672/88A AU613656C (en) 1987-08-14 1988-08-12 Ethers and thioethers having therapeutical activity, their preparation and pharmaceutical compositions containing them
US07/559,036 US5212316A (en) 1987-08-14 1990-07-30 Ethers and thioethers having therapeutical activity, their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21657/87A IT1222500B (it) 1987-08-14 1987-08-14 Eteri e tioteri ad attivita' terapeutica,loro preparazione e composizioni che li contengono

Publications (2)

Publication Number Publication Date
IT8721657A0 IT8721657A0 (it) 1987-08-14
IT1222500B true IT1222500B (it) 1990-09-05

Family

ID=11184932

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21657/87A IT1222500B (it) 1987-08-14 1987-08-14 Eteri e tioteri ad attivita' terapeutica,loro preparazione e composizioni che li contengono

Country Status (15)

Country Link
US (1) US4968706A (it)
EP (1) EP0303227B1 (it)
JP (1) JPS6490149A (it)
AT (1) ATE72433T1 (it)
CA (1) CA1326668C (it)
DD (1) DD277069A5 (it)
DE (1) DE3868302D1 (it)
DK (1) DK449788A (it)
ES (1) ES2034062T3 (it)
FI (1) FI883730A (it)
HU (1) HU201749B (it)
IT (1) IT1222500B (it)
NZ (1) NZ225800A (it)
PT (1) PT88242B (it)
ZA (1) ZA885932B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268007A (en) * 1986-12-29 1993-12-07 The Lubrizol Corporation Dioxolanes and thio analogs, derivatives thereof and lubricants and fuels containing same
JP4653966B2 (ja) * 2004-04-19 2011-03-16 ダイセル化学工業株式会社 ２−ベンゾイルオキシアセトアルデヒド誘導体の製造法
DE102012003286A1 (de) * 2012-02-20 2013-08-22 Merz Pharma Gmbh & Co. Kgaa Kombination aus Lipidtransferproteinen und Phenolderivate enthaltenden Pflanzenstoffen mit lokal-mucosaler Effizienz

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097581A (en) * 1975-12-12 1978-06-27 Ciba-Geigy Corporation Dioxolane derivatives
GB8314521D0 (en) * 1983-05-25 1983-06-29 Pickett J A Behaviour modifying compounds

Also Published As

Publication number Publication date
DK449788A (da) 1989-02-15
FI883730A (fi) 1989-02-15
ZA885932B (en) 1989-04-26
US4968706A (en) 1990-11-06
NZ225800A (en) 1990-07-26
ES2034062T3 (es) 1993-04-01
ATE72433T1 (de) 1992-02-15
JPS6490149A (en) 1989-04-06
EP0303227B1 (en) 1992-02-05
DK449788D0 (da) 1988-08-11
CA1326668C (en) 1994-02-01
AU2067288A (en) 1989-02-16
DD277069A5 (de) 1990-03-21
HUT49110A (en) 1989-08-28
FI883730A0 (fi) 1988-08-11
EP0303227A1 (en) 1989-02-15
IT8721657A0 (it) 1987-08-14
PT88242A (pt) 1989-06-30
HU201749B (en) 1990-12-28
AU613656B2 (en) 1991-08-08
DE3868302D1 (de) 1992-03-19
PT88242B (pt) 1995-03-01

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