JPS6477855A - Liquid chromatograph mass analyzer - Google Patents

Abstract

PURPOSE:To maintain the flow of a sample solution oozed out from a porous member regardless of the mixing ratio of the moving phase by controlling a valve to regulate the flow of the sample solution which is fed to the target surface responding to the mixing ratio of the moving phase. CONSTITUTION:By converting the mixing ratio of the moving phase introduced to a liquid chromatograph 8 by a gradient controller 13, the flow of a sample solution oozed out from a porous member 10 is converted by the variation of viscosity of the moving phase following the variation of the mixing ratio. From the variation of the flow of the sample solution in such a way, the gas molecule amount generated from the sample solution is converted responding to the above variation, and the pressure in an ion source 2 is converted responding to the flow variation of the sample solution. The pressure signal in the ion source 2 obtained from a vacuum gauge 14 is compared with the standard signal from a standard power supply 16, and by controlling a flow regulation valve 12 depending on a difference signal between the both signals, the pressure in the ion source 2 can be maintained at a specific value responding to the standard signal, and the flow of the sample solution oozed out from the porous member 10 can be maintained constant regardless of the variation of the viscosity of the moving phase.