JPS646221A - Production of substituted acetylene compound - Google Patents

Production of substituted acetylene compound

Info

Publication number
JPS646221A
JPS646221A JP63058804A JP5880488A JPS646221A JP S646221 A JPS646221 A JP S646221A JP 63058804 A JP63058804 A JP 63058804A JP 5880488 A JP5880488 A JP 5880488A JP S646221 A JPS646221 A JP S646221A
Authority
JP
Japan
Prior art keywords
formula
reaction
compound
saturated
hydrocarbon group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP63058804A
Other languages
Japanese (ja)
Inventor
Yuzuru Saito
Kokichi Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP63058804A priority Critical patent/JPS646221A/en
Publication of JPS646221A publication Critical patent/JPS646221A/en
Pending legal-status Critical Current

Links

Classifications

    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/52Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Abstract

PURPOSE:To obtain the titled compound advantageously, by subjecting an organic monohalogen compound or sulfonic acid aryl ester and a metallic acetylide to coupling reaction in the presence of an alkyl-2-imidazolidinone as a reaction promoter. CONSTITUTION:A compound shown by the formula A-X (A is 1-20C saturated or unsaturated aliphatic hydrocarbon group which may contain a substituent group inactive in reaction; X is halogen or aryl-sulfonyloxy) is reacted with a compound shown by the formula M-CidenticalC-B (M is alkali metal; B is H, saturated or unsaturated hydrocarbon group which may contain a sub substituent group inactive in reaction or saturated or unsaturated hydrocarbon group containing substituent group shown by the formula -CidenticalC-M) in the presence of a compound shown by the formula (R1 and R2 are lower alkyl; R<3> is H or lower alkyl) as a reaction promoter to give a substituted acetylene compound useful as a drug, agricultural chemical, chemical or an intermediate thereof in high yield, in high purity and in good reproducibility.
JP63058804A 1987-03-11 1988-03-11 Production of substituted acetylene compound Pending JPS646221A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP63058804A JPS646221A (en) 1987-03-11 1988-03-11 Production of substituted acetylene compound

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5637187 1987-03-11
JP63058804A JPS646221A (en) 1987-03-11 1988-03-11 Production of substituted acetylene compound

Publications (1)

Publication Number Publication Date
JPS646221A true JPS646221A (en) 1989-01-10

Family

ID=26397320

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63058804A Pending JPS646221A (en) 1987-03-11 1988-03-11 Production of substituted acetylene compound

Country Status (1)

Country Link
JP (1) JPS646221A (en)

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