JPS6445335A - Halogen-containing alpha-ketones and production thereof - Google Patents

Halogen-containing alpha-ketones and production thereof

Info

Publication number
JPS6445335A
JPS6445335A JP20186787A JP20186787A JPS6445335A JP S6445335 A JPS6445335 A JP S6445335A JP 20186787 A JP20186787 A JP 20186787A JP 20186787 A JP20186787 A JP 20186787A JP S6445335 A JPS6445335 A JP S6445335A
Authority
JP
Japan
Prior art keywords
formula
hydrocarbon group
expressed
halogenated hydrocarbon
ketones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP20186787A
Other languages
Japanese (ja)
Inventor
Yasushi Matsumura
Arata Yasuda
Keiichi Uchida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGC Inc
Original Assignee
Asahi Glass Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Glass Co Ltd filed Critical Asahi Glass Co Ltd
Priority to JP20186787A priority Critical patent/JPS6445335A/en
Publication of JPS6445335A publication Critical patent/JPS6445335A/en
Pending legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:Halogen-containing alpha-keto acids expressed by formula I (R<1> is halogenated hydrocarbon group; R<2> is H, hydrocarbon group or halogenated hydrocarbon group). EXAMPLE:5,5,5-Trifluoro-4-methyl-2-oxo-pentanoic acid. USE:The compound expressed by formula I is a useful substance in the metabolism process in vitro and useful as a substance for application to medicine or agricultural chemical and as an intermediate raw material for medicine such as Vitamin or antibiotic, agricultural chemical, amino acid, perfume or dye. PREPARATION:Aldehydes or ketones having halogenated hydrocarbon group expressed by formula II is reacted with isocyanolactic acids expressed by formula III (R<3> is H or residue of hydroxy compound) in the presence of a strong base and then the resultant product is hydrolyzed to provide the compound expressed by formula I. The reaction temperature is in the range of -100-100 deg.C, preferably -78-25 deg.C.
JP20186787A 1987-08-14 1987-08-14 Halogen-containing alpha-ketones and production thereof Pending JPS6445335A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP20186787A JPS6445335A (en) 1987-08-14 1987-08-14 Halogen-containing alpha-ketones and production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20186787A JPS6445335A (en) 1987-08-14 1987-08-14 Halogen-containing alpha-ketones and production thereof

Publications (1)

Publication Number Publication Date
JPS6445335A true JPS6445335A (en) 1989-02-17

Family

ID=16448202

Family Applications (1)

Application Number Title Priority Date Filing Date
JP20186787A Pending JPS6445335A (en) 1987-08-14 1987-08-14 Halogen-containing alpha-ketones and production thereof

Country Status (1)

Country Link
JP (1) JPS6445335A (en)

Similar Documents

Publication Publication Date Title
AU6758881A (en) Preparation of esters of naphthyl-propionic acids
JPS6445335A (en) Halogen-containing alpha-ketones and production thereof
DE69616470D1 (en) Process for the preparation of dialkylsuccinylsuccinates
FR2446806A1 (en) PROCESS FOR THE MANUFACTURE OF ALDONIC ACIDS BY ENZYMATICS
JPS6479168A (en) Novel synthesis of 6,5-diacyl-7-deacetylforskolin derivative and intermediate
US3960884A (en) Method of preparing racemic biotin
JPS5515408A (en) Novel mitomycin derivative and its preparation
JPS5781460A (en) Novel indolinecarboxylic acid derivative
DE3061787D1 (en) Process for preparing derivatives of 6-amino-6-desoxy-2,3-0-isopropylidene-alpha-l-sorbofuranose and intermediates of the process
US2461701A (en) Conversion of alpha amino acids to alpha hydroxy acids
CA2092407A1 (en) Process for the preparation of 2,3-difluoro-6-nitrophenol
RU95103392A (en) Method of synthesis of 1-hydroxyadamantane
GB1468758A (en) Industrial process for the synthesis of 2,6-dihydroxy-cineole through pinol from highly pure sobrerol products thus obtained and use thereof in pharmaceutical field
EP0293244A3 (en) N epsilon-trifluoroacetyl-l-lysyl-l-proline.d-1o-camphorsulfonic acid salt and process for producing the same
AU4782490A (en) A process for the preparation of a mixture of sucrose oxidation products and the use thereof
US2927118A (en) L(+)-isoglutamine compounds and process of preparing same
ES8506689A1 (en) Cumalincarboxylic-acid esters, process for their preparation and agricultural fungicides.
ES8107190A1 (en) Process for the preparation of omega -lactams, in particular caprolactam
JPS5430144A (en) Preparation of isocamphane
EP0111569A4 (en) Hydroxyalkanesulfonic acids and their derivatives, and process for their preparation.
JPS6452754A (en) Dichloroindolineacetic acid derivative and production thereof
JPS6460391A (en) Production of gamma-halo-beta(r)-hydroxybutyric acid ester
JPS6439998A (en) Production of fr-900482 substance
JPS6445336A (en) Production of 2-(r)-hydroxy-4-phenyllactic acid derivative
JPS5599073A (en) Production of artificial antigen containing melatonin residue