JPS6442421A - Calcium antagonistic agent - Google Patents
Calcium antagonistic agentInfo
- Publication number
- JPS6442421A JPS6442421A JP19819687A JP19819687A JPS6442421A JP S6442421 A JPS6442421 A JP S6442421A JP 19819687 A JP19819687 A JP 19819687A JP 19819687 A JP19819687 A JP 19819687A JP S6442421 A JPS6442421 A JP S6442421A
- Authority
- JP
- Japan
- Prior art keywords
- gomisin
- formula
- active component
- extraction
- calcium antagonistic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE:To obtain a calcium antagonistic agent having hypotensive action and useful as a safe drug, by using gomisin H, gomisin J, gomisin N or gomisin G as an active component. CONSTITUTION:The objective agent contains gomisin H or formula I, gomisin J of formula II, gomisin N of formula III or gomisin G of formula IV as an active component. The compound of the active component can be produced e.g. by extracting KITAGOMISHI (fruit of Schizandra chinensis, a kind of herb drug) with lower hydrocarbons and removing the solvent and volatile components from the extract. The lower hydrocarbons to be used in the extraction process are e.g. petroleum ether, n-hexane or benzene. The extraction is carried out at a temperature between room temperature and the boiling point of the extraction solvent, preferably under refluxing.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP19819687A JPS6442421A (en) | 1987-08-10 | 1987-08-10 | Calcium antagonistic agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP19819687A JPS6442421A (en) | 1987-08-10 | 1987-08-10 | Calcium antagonistic agent |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6442421A true JPS6442421A (en) | 1989-02-14 |
Family
ID=16387069
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP19819687A Pending JPS6442421A (en) | 1987-08-10 | 1987-08-10 | Calcium antagonistic agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6442421A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100380634B1 (en) * | 2000-10-19 | 2003-04-26 | 주식회사 엘컴사이언스 | Composition containing a dibenzocyclooctane lignan derivative for prevention or treatment of neurodegenerative disease |
KR100559488B1 (en) * | 2002-07-22 | 2006-03-10 | 고제상 | Inhibitor for transcription of NFAT isolated from Schisandra chinensis |
-
1987
- 1987-08-10 JP JP19819687A patent/JPS6442421A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100380634B1 (en) * | 2000-10-19 | 2003-04-26 | 주식회사 엘컴사이언스 | Composition containing a dibenzocyclooctane lignan derivative for prevention or treatment of neurodegenerative disease |
KR100559488B1 (en) * | 2002-07-22 | 2006-03-10 | 고제상 | Inhibitor for transcription of NFAT isolated from Schisandra chinensis |
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