JPS6442421A - Calcium antagonistic agent - Google Patents

Calcium antagonistic agent

Info

Publication number
JPS6442421A
JPS6442421A JP19819687A JP19819687A JPS6442421A JP S6442421 A JPS6442421 A JP S6442421A JP 19819687 A JP19819687 A JP 19819687A JP 19819687 A JP19819687 A JP 19819687A JP S6442421 A JPS6442421 A JP S6442421A
Authority
JP
Japan
Prior art keywords
gomisin
formula
active component
extraction
calcium antagonistic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP19819687A
Other languages
Japanese (ja)
Inventor
Mamoru Suekawa
Takashi Shiga
Hideko Sone
Yukinobu Iketani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tsumura and Co
Original Assignee
Tsumura and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tsumura and Co filed Critical Tsumura and Co
Priority to JP19819687A priority Critical patent/JPS6442421A/en
Publication of JPS6442421A publication Critical patent/JPS6442421A/en
Pending legal-status Critical Current

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Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE:To obtain a calcium antagonistic agent having hypotensive action and useful as a safe drug, by using gomisin H, gomisin J, gomisin N or gomisin G as an active component. CONSTITUTION:The objective agent contains gomisin H or formula I, gomisin J of formula II, gomisin N of formula III or gomisin G of formula IV as an active component. The compound of the active component can be produced e.g. by extracting KITAGOMISHI (fruit of Schizandra chinensis, a kind of herb drug) with lower hydrocarbons and removing the solvent and volatile components from the extract. The lower hydrocarbons to be used in the extraction process are e.g. petroleum ether, n-hexane or benzene. The extraction is carried out at a temperature between room temperature and the boiling point of the extraction solvent, preferably under refluxing.
JP19819687A 1987-08-10 1987-08-10 Calcium antagonistic agent Pending JPS6442421A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP19819687A JPS6442421A (en) 1987-08-10 1987-08-10 Calcium antagonistic agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP19819687A JPS6442421A (en) 1987-08-10 1987-08-10 Calcium antagonistic agent

Publications (1)

Publication Number Publication Date
JPS6442421A true JPS6442421A (en) 1989-02-14

Family

ID=16387069

Family Applications (1)

Application Number Title Priority Date Filing Date
JP19819687A Pending JPS6442421A (en) 1987-08-10 1987-08-10 Calcium antagonistic agent

Country Status (1)

Country Link
JP (1) JPS6442421A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100380634B1 (en) * 2000-10-19 2003-04-26 주식회사 엘컴사이언스 Composition containing a dibenzocyclooctane lignan derivative for prevention or treatment of neurodegenerative disease
KR100559488B1 (en) * 2002-07-22 2006-03-10 고제상 Inhibitor for transcription of NFAT isolated from Schisandra chinensis

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100380634B1 (en) * 2000-10-19 2003-04-26 주식회사 엘컴사이언스 Composition containing a dibenzocyclooctane lignan derivative for prevention or treatment of neurodegenerative disease
KR100559488B1 (en) * 2002-07-22 2006-03-10 고제상 Inhibitor for transcription of NFAT isolated from Schisandra chinensis

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