JPS6371639A - 試薬被覆光源を用いた流体の分析装置及び方法並びにそれに用いる発光ダイオード - Google Patents
試薬被覆光源を用いた流体の分析装置及び方法並びにそれに用いる発光ダイオードInfo
- Publication number
- JPS6371639A JPS6371639A JP62225433A JP22543387A JPS6371639A JP S6371639 A JPS6371639 A JP S6371639A JP 62225433 A JP62225433 A JP 62225433A JP 22543387 A JP22543387 A JP 22543387A JP S6371639 A JPS6371639 A JP S6371639A
- Authority
- JP
- Japan
- Prior art keywords
- light
- coating
- ligand
- light source
- reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- KHPXUQMNIQBQEV-UHFFFAOYSA-N oxaloacetic acid Chemical compound OC(=O)CC(=O)C(O)=O KHPXUQMNIQBQEV-UHFFFAOYSA-N 0.000 description 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 description 1
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- 229960001723 oxytocin Drugs 0.000 description 1
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- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 229960002695 phenobarbital Drugs 0.000 description 1
- DDBREPKUVSBGFI-UHFFFAOYSA-N phenobarbital Chemical compound C=1C=CC=CC=1C1(CC)C(=O)NC(=O)NC1=O DDBREPKUVSBGFI-UHFFFAOYSA-N 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
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- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 description 1
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- 229960005456 sisomicin Drugs 0.000 description 1
- URWAJWIAIPFPJE-YFMIWBNJSA-N sisomycin Chemical compound O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CC=C(CN)O2)N)[C@@H](N)C[C@H]1N URWAJWIAIPFPJE-YFMIWBNJSA-N 0.000 description 1
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- 150000003522 tetracyclines Chemical class 0.000 description 1
- 229960000278 theophylline Drugs 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- 239000011721 thiamine Substances 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 229960004072 thrombin Drugs 0.000 description 1
- 229940104230 thymidine Drugs 0.000 description 1
- 229960000874 thyrotropin Drugs 0.000 description 1
- 230000001748 thyrotropin Effects 0.000 description 1
- 229940034208 thyroxine Drugs 0.000 description 1
- 229960000707 tobramycin Drugs 0.000 description 1
- NLVFBUXFDBBNBW-PBSUHMDJSA-S tobramycin(5+) Chemical compound [NH3+][C@@H]1C[C@H](O)[C@@H](C[NH3+])O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H]([NH3+])[C@H](O)[C@@H](CO)O2)O)[C@H]([NH3+])C[C@@H]1[NH3+] NLVFBUXFDBBNBW-PBSUHMDJSA-S 0.000 description 1
- 239000012581 transferrin Substances 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 1
- 229910052721 tungsten Inorganic materials 0.000 description 1
- 239000010937 tungsten Substances 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
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- 239000000080 wetting agent Substances 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
- SFVVQRJOGUKCEG-OPQSFPLASA-N β-MSH Chemical compound C1C[C@@H](O)[C@H]2C(COC(=O)[C@@](O)([C@@H](C)O)C(C)C)=CCN21 SFVVQRJOGUKCEG-OPQSFPLASA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/255—Details, e.g. use of specially adapted sources, lighting or optical systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/808—Optical sensing apparatus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Engineering & Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Led Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/906,086 US4717545A (en) | 1986-09-11 | 1986-09-11 | Device and method for chemical analysis of fluids with a reagent coated light source |
| US906086 | 1986-09-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6371639A true JPS6371639A (ja) | 1988-04-01 |
| JPH0145021B2 JPH0145021B2 (OSRAM) | 1989-10-02 |
Family
ID=25421905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62225433A Granted JPS6371639A (ja) | 1986-09-11 | 1987-09-10 | 試薬被覆光源を用いた流体の分析装置及び方法並びにそれに用いる発光ダイオード |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4717545A (OSRAM) |
| EP (1) | EP0265630B1 (OSRAM) |
| JP (1) | JPS6371639A (OSRAM) |
| AU (1) | AU580719B2 (OSRAM) |
| CA (2) | CA1302120C (OSRAM) |
| DE (1) | DE3777947D1 (OSRAM) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3319526C2 (de) * | 1983-05-28 | 1994-10-20 | Max Planck Gesellschaft | Anordnung mit einem physikalischen Sensor |
| US4820490A (en) * | 1986-09-11 | 1989-04-11 | Miles Inc. | Device and method for chemical analysis of fluids with a reagent coated light source |
| US4818491A (en) * | 1988-03-14 | 1989-04-04 | Sun Du Jour, Inc. | Suntanning gauge |
| US7141212B2 (en) * | 1993-11-12 | 2006-11-28 | Inverness Medical Switzerland Gmbh | Reading devices and assay devices for use therewith |
| ZA948782B (en) * | 1993-11-12 | 1996-05-07 | Unipath Ltd | Reading devices and assay devices for use therewith |
| US5728352A (en) * | 1994-11-14 | 1998-03-17 | Advanced Care Products | Disposable electronic diagnostic instrument |
| US5598005A (en) * | 1995-02-15 | 1997-01-28 | The United States Of America As Represented By The Secretary Of The Commerce | Non-destructive method for determining the extent of cure of a polymerizing material and the solidification of a thermoplastic polymer based on wavelength shift of fluroescence |
| AT404514B (de) * | 1996-11-06 | 1998-12-28 | Robert Dr Kellner | Vorrichtung und verfahren zur messung der konzentration von stoffen in flüssigkeiten |
| IES20000617A2 (en) | 2000-08-02 | 2002-02-20 | Millipore Ireland Bv | Optical scattering monitor |
| DE10056704C2 (de) * | 2000-11-15 | 2003-01-09 | Hermann Von Lilienfeld-Toal | Quantitative Bestimmung von Stoffen mittels IR-Spektroskopie |
| GB0127861D0 (en) * | 2001-11-20 | 2002-01-16 | Biotrace Ltd | Absorbance monitoring |
| US7141369B2 (en) * | 2002-04-25 | 2006-11-28 | Semibio Technology, Inc. | Measuring cellular metabolism of immobilized cells |
| GB0324784D0 (en) * | 2003-10-24 | 2003-11-26 | Biotrace Ltd | Bioluminescence monitor |
| US7256888B2 (en) * | 2003-11-07 | 2007-08-14 | Cardial Health 303, Inc. | Fluid verification system and method for infusions |
| US7763454B2 (en) * | 2004-07-09 | 2010-07-27 | Church & Dwight Co., Inc. | Electronic analyte assaying device |
| US20110143378A1 (en) * | 2009-11-12 | 2011-06-16 | CyVek LLC. | Microfluidic method and apparatus for high performance biological assays |
| US9700889B2 (en) | 2009-11-23 | 2017-07-11 | Cyvek, Inc. | Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results |
| US9855735B2 (en) | 2009-11-23 | 2018-01-02 | Cyvek, Inc. | Portable microfluidic assay devices and methods of manufacture and use |
| US9759718B2 (en) | 2009-11-23 | 2017-09-12 | Cyvek, Inc. | PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use |
| US9500645B2 (en) | 2009-11-23 | 2016-11-22 | Cyvek, Inc. | Micro-tube particles for microfluidic assays and methods of manufacture |
| US9651568B2 (en) | 2009-11-23 | 2017-05-16 | Cyvek, Inc. | Methods and systems for epi-fluorescent monitoring and scanning for microfluidic assays |
| ES2649559T3 (es) | 2009-11-23 | 2018-01-12 | Cyvek, Inc. | Método y aparato para realizar ensayos |
| US10065403B2 (en) | 2009-11-23 | 2018-09-04 | Cyvek, Inc. | Microfluidic assay assemblies and methods of manufacture |
| WO2013134742A2 (en) | 2012-03-08 | 2013-09-12 | Cyvek, Inc | Micro-tube particles for microfluidic assays and methods of manufacture |
| WO2012129455A2 (en) | 2011-03-22 | 2012-09-27 | Cyvek, Inc | Microfluidic devices and methods of manufacture and use |
| US10591474B2 (en) * | 2015-06-03 | 2020-03-17 | Arizona Board Of Regents On Behalf Of Arizona State University | Point-of-care fluorescent immunoassay for identifying biomarkers in patient biofluid samples |
| US10228367B2 (en) | 2015-12-01 | 2019-03-12 | ProteinSimple | Segmented multi-use automated assay cartridge |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4050895A (en) * | 1975-09-26 | 1977-09-27 | Monsanto Research Corporation | Optical analytical device, waveguide and method |
| DE2833356A1 (de) * | 1978-07-29 | 1980-02-14 | Max Planck Gesellschaft | Verfahren zur optischen messung von stoffkonzentrationen |
| US4399099A (en) * | 1979-09-20 | 1983-08-16 | Buckles Richard G | Optical fiber apparatus for quantitative analysis |
| US4321057A (en) * | 1979-09-20 | 1982-03-23 | Buckles Richard G | Method for quantitative analysis using optical fibers |
| US4380585A (en) * | 1979-11-13 | 1983-04-19 | Miles Laboratories, Inc. | Stabilization of benzidine-type indicators with various enhancers |
| US4368047A (en) * | 1981-04-27 | 1983-01-11 | University Of Utah Research Foundation | Process for conducting fluorescence immunoassays without added labels and employing attenuated internal reflection |
| US4582809A (en) * | 1982-06-14 | 1986-04-15 | Myron J. Block | Apparatus including optical fiber for fluorescence immunoassay |
| US4447546A (en) * | 1982-08-23 | 1984-05-08 | Myron J. Block | Fluorescent immunoassay employing optical fiber in capillary tube |
| DE3319526C2 (de) * | 1983-05-28 | 1994-10-20 | Max Planck Gesellschaft | Anordnung mit einem physikalischen Sensor |
| SE8403648L (sv) * | 1984-07-10 | 1986-01-11 | Ragnar Winberg | Apparat for optisk metning av vetskor |
| JPS6183930A (ja) * | 1984-09-29 | 1986-04-28 | Toshiba Corp | 圧力・差圧伝送器 |
| DE3481644D1 (de) * | 1984-12-10 | 1990-04-19 | Prutec Ltd | Verfahren zum optischen nachweis von parametern von substanzen in einem fluessigen analyt. |
| US4815843A (en) * | 1985-05-29 | 1989-03-28 | Oerlikon-Buhrle Holding Ag | Optical sensor for selective detection of substances and/or for the detection of refractive index changes in gaseous, liquid, solid and porous samples |
-
1986
- 1986-09-11 US US06/906,086 patent/US4717545A/en not_active Expired - Fee Related
-
1987
- 1987-07-22 CA CA000542715A patent/CA1302120C/en not_active Expired - Lifetime
- 1987-08-20 AU AU77253/87A patent/AU580719B2/en not_active Ceased
- 1987-09-01 DE DE8787112721T patent/DE3777947D1/de not_active Expired - Lifetime
- 1987-09-01 EP EP87112721A patent/EP0265630B1/en not_active Expired
- 1987-09-10 JP JP62225433A patent/JPS6371639A/ja active Granted
-
1991
- 1991-10-02 CA CA000616189A patent/CA1317122C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0265630A3 (en) | 1989-11-23 |
| US4717545A (en) | 1988-01-05 |
| EP0265630A2 (en) | 1988-05-04 |
| JPH0145021B2 (OSRAM) | 1989-10-02 |
| DE3777947D1 (de) | 1992-05-07 |
| AU7725387A (en) | 1988-03-17 |
| EP0265630B1 (en) | 1992-04-01 |
| CA1302120C (en) | 1992-06-02 |
| CA1317122C (en) | 1993-05-04 |
| AU580719B2 (en) | 1989-01-27 |
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