JPS6345669B2 - - Google Patents

Info

Publication number
JPS6345669B2
JPS6345669B2 JP56041752A JP4175281A JPS6345669B2 JP S6345669 B2 JPS6345669 B2 JP S6345669B2 JP 56041752 A JP56041752 A JP 56041752A JP 4175281 A JP4175281 A JP 4175281A JP S6345669 B2 JPS6345669 B2 JP S6345669B2
Authority
JP
Japan
Prior art keywords
test
general formula
pharmaceutical composition
present
bis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP56041752A
Other languages
English (en)
Japanese (ja)
Other versions
JPS57156466A (en
Inventor
Isao Sakano
Tatsuro Yokoyama
Seitaro Kajitani
Yutaka Okazaki
Hiroshi Tokuda
Hiroshi Kawamo
Mikio Kumakura
Akira Awaya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP56041752A priority Critical patent/JPS57156466A/ja
Priority to EP82900992A priority patent/EP0074413B1/en
Priority to US06/444,571 priority patent/US4524147A/en
Priority to PCT/JP1982/000081 priority patent/WO1982003392A1/ja
Priority to DE3239719T priority patent/DE3239719C2/de
Priority to GB08232544A priority patent/GB2109377B/en
Publication of JPS57156466A publication Critical patent/JPS57156466A/ja
Publication of JPS6345669B2 publication Critical patent/JPS6345669B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP56041752A 1981-03-24 1981-03-24 Uracil derivative and medicinal composition containing the same Granted JPS57156466A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP56041752A JPS57156466A (en) 1981-03-24 1981-03-24 Uracil derivative and medicinal composition containing the same
EP82900992A EP0074413B1 (en) 1981-03-24 1982-03-24 Uracil derivatives, process for their preparation, and medicinal composition containing same
US06/444,571 US4524147A (en) 1981-03-24 1982-03-24 Uracil derivatives, process for preparing same, and pharmaceutical compositions comprising same
PCT/JP1982/000081 WO1982003392A1 (en) 1981-03-24 1982-03-24 Uracil derivatives,process for their preparation,and medicinal composition containing same
DE3239719T DE3239719C2 (de) 1981-03-24 1982-03-24 Uracil-Derivate, Verfahren zu ihrer Herstellung und dieselben enthaltende pharmazeutische Zusammensetzungen
GB08232544A GB2109377B (en) 1981-03-24 1982-03-24 Uracil derivatives, process for their preparation, and medicinal composition containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56041752A JPS57156466A (en) 1981-03-24 1981-03-24 Uracil derivative and medicinal composition containing the same

Publications (2)

Publication Number Publication Date
JPS57156466A JPS57156466A (en) 1982-09-27
JPS6345669B2 true JPS6345669B2 (en, 2012) 1988-09-12

Family

ID=12617145

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56041752A Granted JPS57156466A (en) 1981-03-24 1981-03-24 Uracil derivative and medicinal composition containing the same

Country Status (6)

Country Link
US (1) US4524147A (en, 2012)
EP (1) EP0074413B1 (en, 2012)
JP (1) JPS57156466A (en, 2012)
DE (1) DE3239719C2 (en, 2012)
GB (1) GB2109377B (en, 2012)
WO (1) WO1982003392A1 (en, 2012)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57156466A (en) * 1981-03-24 1982-09-27 Mitsui Toatsu Chem Inc Uracil derivative and medicinal composition containing the same
KR100318519B1 (ko) * 1993-09-27 2002-04-06 허일섭 우라실을 유효성분으로 함유하는 관절염치료제
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3532699A (en) * 1968-07-12 1970-10-06 Du Pont Herbicidal poly uracils
JPS57156466A (en) * 1981-03-24 1982-09-27 Mitsui Toatsu Chem Inc Uracil derivative and medicinal composition containing the same

Also Published As

Publication number Publication date
DE3239719C2 (de) 1985-08-22
EP0074413A4 (en) 1983-08-03
US4524147A (en) 1985-06-18
GB2109377B (en) 1985-01-30
DE3239719T1 (de) 1983-03-24
EP0074413B1 (en) 1985-05-08
JPS57156466A (en) 1982-09-27
GB2109377A (en) 1983-06-02
EP0074413A1 (en) 1983-03-23
WO1982003392A1 (en) 1982-10-14

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