JPS63211209A - Cosmetic - Google Patents
CosmeticInfo
- Publication number
- JPS63211209A JPS63211209A JP62046545A JP4654587A JPS63211209A JP S63211209 A JPS63211209 A JP S63211209A JP 62046545 A JP62046545 A JP 62046545A JP 4654587 A JP4654587 A JP 4654587A JP S63211209 A JPS63211209 A JP S63211209A
- Authority
- JP
- Japan
- Prior art keywords
- component
- acid
- cosmetic
- weight
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002537 cosmetic Substances 0.000 title claims abstract description 20
- -1 fatty acid ester Chemical class 0.000 claims abstract description 15
- 239000000287 crude extract Substances 0.000 claims abstract description 11
- 239000007788 liquid Substances 0.000 claims abstract description 9
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 8
- 229930195729 fatty acid Natural products 0.000 claims abstract description 8
- 239000000194 fatty acid Substances 0.000 claims abstract description 8
- 150000005846 sugar alcohols Polymers 0.000 claims abstract description 8
- 239000002253 acid Substances 0.000 claims description 12
- 239000000284 extract Substances 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 8
- NEULYSAPCBXJEG-UHFFFAOYSA-N Lansic Acid Natural products CC(=C)C1CCC(=C)C(CCC2C(=CCC3C(=C)C(CCC23C)C(=O)O)C)C1(C)CCC(=O)O NEULYSAPCBXJEG-UHFFFAOYSA-N 0.000 abstract 3
- 235000006686 Lansium domesticum Nutrition 0.000 abstract 3
- 244000121765 Lansium domesticum Species 0.000 abstract 3
- SYTWWAZKYVYTTQ-SUAVODKESA-N lansic acid Chemical compound OC(=O)CC[C@@]1(C)[C@H](C(=C)C)CCC(=C)[C@@H]1CC[C@@H]1[C@](CCC(O)=O)(C)[C@H](C(C)=C)CC=C1C SYTWWAZKYVYTTQ-SUAVODKESA-N 0.000 abstract 3
- 229930184943 Lansioside Natural products 0.000 abstract 2
- 238000013329 compounding Methods 0.000 abstract 2
- BJDAUCLANVMIOB-UHFFFAOYSA-N (3-decanoyloxy-2,2-dimethylpropyl) decanoate Chemical compound CCCCCCCCCC(=O)OCC(C)(C)COC(=O)CCCCCCCCC BJDAUCLANVMIOB-UHFFFAOYSA-N 0.000 abstract 1
- 241001071861 Lethrinus genivittatus Species 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 31
- 239000004615 ingredient Substances 0.000 description 18
- 235000019441 ethanol Nutrition 0.000 description 12
- 238000003756 stirring Methods 0.000 description 12
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 239000000203 mixture Substances 0.000 description 8
- 239000008213 purified water Substances 0.000 description 8
- 238000007796 conventional method Methods 0.000 description 7
- 239000006071 cream Substances 0.000 description 7
- 239000006210 lotion Substances 0.000 description 7
- 235000015961 tonic Nutrition 0.000 description 7
- 230000001256 tonic effect Effects 0.000 description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
- 150000002148 esters Chemical class 0.000 description 6
- 239000003205 fragrance Substances 0.000 description 6
- 210000003491 skin Anatomy 0.000 description 6
- 208000001840 Dandruff Diseases 0.000 description 5
- 231100000245 skin permeability Toxicity 0.000 description 5
- 125000004432 carbon atom Chemical group C* 0.000 description 4
- 239000003755 preservative agent Substances 0.000 description 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 3
- 229940041616 menthol Drugs 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 239000002453 shampoo Substances 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 description 2
- OBETXYAYXDNJHR-UHFFFAOYSA-N 2-Ethylhexanoic acid Chemical compound CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 2
- 108010066551 Cholestenone 5 alpha-Reductase Proteins 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 230000001166 anti-perspirative effect Effects 0.000 description 2
- 239000003213 antiperspirant Substances 0.000 description 2
- 239000004359 castor oil Substances 0.000 description 2
- 235000019438 castor oil Nutrition 0.000 description 2
- 239000008294 cold cream Substances 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 210000004761 scalp Anatomy 0.000 description 2
- 210000004927 skin cell Anatomy 0.000 description 2
- 159000000000 sodium salts Chemical class 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- WFXHUBZUIFLWCV-UHFFFAOYSA-N (2,2-dimethyl-3-octanoyloxypropyl) octanoate Chemical compound CCCCCCCC(=O)OCC(C)(C)COC(=O)CCCCCCC WFXHUBZUIFLWCV-UHFFFAOYSA-N 0.000 description 1
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical compound OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 201000004384 Alopecia Diseases 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- 206010039792 Seborrhoea Diseases 0.000 description 1
- LDDUCKDUDZVHLN-UHFFFAOYSA-N [2-hydroxy-3-[2-hydroxy-3-(16-methylheptadecanoyloxy)propoxy]propyl] 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCC(O)COCC(O)COC(=O)CCCCCCCCCCCCCCC(C)C LDDUCKDUDZVHLN-UHFFFAOYSA-N 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 229940087168 alpha tocopherol Drugs 0.000 description 1
- 201000002996 androgenic alopecia Diseases 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 230000003915 cell function Effects 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- GHVNFZFCNZKVNT-UHFFFAOYSA-M decanoate Chemical compound CCCCCCCCCC([O-])=O GHVNFZFCNZKVNT-UHFFFAOYSA-M 0.000 description 1
- 229940105990 diglycerin Drugs 0.000 description 1
- GPLRAVKSCUXZTP-UHFFFAOYSA-N diglycerol Chemical compound OCC(O)COCC(O)CO GPLRAVKSCUXZTP-UHFFFAOYSA-N 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- UWLPCYBIJSLGQO-UHFFFAOYSA-N dodecanoic acid;propane-1,2,3-triol Chemical compound OCC(O)CO.CCCCCCCCCCCC(O)=O UWLPCYBIJSLGQO-UHFFFAOYSA-N 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003676 hair preparation Substances 0.000 description 1
- 239000008266 hair spray Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 229940057995 liquid paraffin Drugs 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- SLCVBVWXLSEKPL-UHFFFAOYSA-N neopentyl glycol Chemical compound OCC(C)(C)CO SLCVBVWXLSEKPL-UHFFFAOYSA-N 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- ZUFQODAHGAHPFQ-UHFFFAOYSA-N pyridoxine hydrochloride Chemical compound Cl.CC1=NC=C(CO)C(CO)=C1O ZUFQODAHGAHPFQ-UHFFFAOYSA-N 0.000 description 1
- 229960004172 pyridoxine hydrochloride Drugs 0.000 description 1
- 235000019171 pyridoxine hydrochloride Nutrition 0.000 description 1
- 239000011764 pyridoxine hydrochloride Substances 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 208000008742 seborrheic dermatitis Diseases 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229940045920 sodium pyrrolidone carboxylate Drugs 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- HYRLWUFWDYFEES-UHFFFAOYSA-M sodium;2-oxopyrrolidine-1-carboxylate Chemical compound [Na+].[O-]C(=O)N1CCCC1=O HYRLWUFWDYFEES-UHFFFAOYSA-M 0.000 description 1
- 230000000475 sunscreen effect Effects 0.000 description 1
- 239000000516 sunscreening agent Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 229960000984 tocofersolan Drugs 0.000 description 1
- 229960000716 tonics Drugs 0.000 description 1
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
Description
【発明の詳細な説明】
発明の分野
本発明は、皮膚細胞機能を活性化し皮膚の保護および美
化に顕著な効果を発揮する、有効成分の皮膚浸透性に優
れたべたつきの少ない化粧料に関する。DETAILED DESCRIPTION OF THE INVENTION Field of the Invention The present invention relates to a cosmetic with low stickiness, which activates skin cell functions, exhibits remarkable effects on skin protection and beautification, and has excellent skin permeability of active ingredients.
発明の背景
一デュークまたはランジウムドメスチカムジャックバー
ランサの果皮より得られた抽出物およびその特定の成分
か5α−リダクターゼの活性を阻害し、男性ホルモンが
関与する男性型脱毛症、尋常性座癒、脂漏、フケ症等の
疾患の予防および治療に効果のあることが知られている
(特開昭60−243020号参照)。BACKGROUND OF THE INVENTION 1. Extract obtained from the pericarp of Duke or Randium domesticum jack balansa and its specific components inhibit the activity of 5α-reductase, thereby treating androgenic alopecia associated with male hormones, locus vulgaris. It is known to be effective in preventing and treating diseases such as healing, seborrhea, and dandruff (see JP-A-60-243020).
このような効果は、5α−リダクターゼ活性の阻害によ
り皮膚細胞のエネルギー産生が増大し細胞が活性化する
ことによって生じるものである。Such effects are caused by the inhibition of 5α-reductase activity, which increases the energy production of skin cells and activates the cells.
したがって、該抽出物等を基剤として配合すれば、男性
ホルモンか関与する種々の皮膚疾患を予防および治療す
ることにより生き生きした肌を再生、維持するのに効果
のある化粧料が得られるしのと期待されろ。Therefore, by blending the extract etc. as a base, it is possible to obtain cosmetics that are effective in preventing and treating various skin diseases related to male hormones, thereby regenerating and maintaining vibrant skin. be expected.
しかしながら、該抽出物等を基剤として配合した化粧料
を肌に塗布した場合、非常にべたつき易く、さっばり感
が要求される化粧料に用いるには不適当であり、また、
該抽出物等の皮膚浸透性がT−k tX−rs k−プ
準ロバh/^h■を−春鵡+1ナハJ、ゼ得られていな
い。そこで、皮膚塗布時のべたつき感を緩和し、かつ、
該抽出物等の皮膚浸透性を高めるような処方が要望され
ている。However, when cosmetics containing such extracts as a base are applied to the skin, they tend to become very sticky, making them unsuitable for use in cosmetics that require a light feel.
The skin permeability of the extract and the like has not been obtained. Therefore, it alleviates the sticky feeling when applied to the skin, and
There is a demand for a formulation that enhances the skin permeability of the extract and the like.
本発明台らは、以上の欠点を改良し、塗布時のべたつき
感がなく、かつ、有効成分の皮膚浸透性を高めた皮膚の
保護および美化に優れた効果を発揮する化粧料を得るべ
く鋭意検討を行なった結果、面記の粗抽出物および/ま
たはその特定の成分をある種の化合物と併用することに
より、良好な特性をiする化粧料が得られることを見出
だし、本発明を完成するに至った。The inventors of the present invention have worked hard to improve the above-mentioned drawbacks and to obtain a cosmetic that does not have a sticky feeling when applied, has enhanced skin permeability of active ingredients, and has excellent skin protection and beautification effects. As a result of their studies, they discovered that a cosmetic with good properties could be obtained by using a crude extract of Menji and/or its specific ingredients in combination with certain compounds, and completed the present invention. I ended up doing it.
発明の開示
本発明は、ランジウムドメスチカムジャックバーデュー
ク(以下、デユーダと称する)またはランジウムドメス
チカムジャックバーランサ(以下、ランサと弥する)の
果皮より得られた粗抽出物、その成分であるランジック
酸、ランジオサイドおよびそれらの誘導体から選ばれる
1種または2種以上および液状多価アルコール脂肪酸エ
ステル類から選ばれる1種または2種以上を配合したこ
とを特徴とする化粧料を提供するものである。DISCLOSURE OF THE INVENTION The present invention relates to a crude extract obtained from the pericarp of Randium domesticum jack barduke (hereinafter referred to as Deuda) or Randium domesticum jack barlantha (hereinafter referred to as Lanza); A cosmetic comprising one or more selected from landic acid, landioside, and derivatives thereof, and one or more selected from liquid polyhydric alcohol fatty acid esters. This is what we provide.
本発明の化粧料に配合するデユーダまたはランサの果皮
より得られる粗抽出物、ランジック酸およびランジオサ
イドの抽出、分離および精製法ならびにその構造は公知
であり(例えば、特開昭60−243020号参照)、
商業的に入手することができる。誘導体としては、ラン
ノック酸の塩(例えば、ナトリウム塩、ニナトリウム塩
など)、エステル(例えば、炭素数2〜12のモノアル
キルエステル、炭素数2〜!2のジアルキルエステルな
ど)、ランジオサイドの塩(例えば、ナトリウム塩、カ
リウム塩など)、エステル(例えば、炭素数2〜12の
モノアルキルエステルなど)などが挙げられ、常法によ
り製造することができろ。ljq記の粗抽出物、ランジ
ック酸、ランジオサイドおよびそれらの誘導体は、ラン
ジック酸として化粧料全量に対して0.01〜3重量%
、好ましくは、0.05〜I重量%配合される。配合量
が0,01重量%より少ないと充分な薬効が得られず、
また3重量%より多いと基剤への溶解が困難になる場合
がある。The extraction, separation and purification methods and structures of the crude extract, randic acid and landiside obtained from the pericarp of Deuda or Langsa to be incorporated into the cosmetics of the present invention are known (for example, JP-A No. 60-243020). reference),
Commercially available. Derivatives include rannoic acid salts (e.g., sodium salt, disodium salt, etc.), esters (e.g., monoalkyl esters having 2 to 12 carbon atoms, dialkyl esters having 2 to !2 carbon atoms, etc.), and randiosides. Examples include salts (eg, sodium salts, potassium salts, etc.), esters (eg, monoalkyl esters having 2 to 12 carbon atoms, etc.), and they can be produced by conventional methods. The crude extract, landic acid, landioside and their derivatives listed in ljq are 0.01 to 3% by weight of the total amount of the cosmetic as randic acid.
, preferably in an amount of 0.05 to I% by weight. If the blending amount is less than 0.01% by weight, sufficient medicinal efficacy will not be obtained,
Moreover, if it exceeds 3% by weight, it may become difficult to dissolve in the base.
本発明の化粧料に配合する液状多価アルコール脂肪酸エ
ステルの多価アルコールとしては、エチレングリコール
、プロピレングリコール、ネオペンデルグリコール、グ
リセリン、ジグリセリン、ソルビタンなどが挙げられ、
脂肪酸としては、炭素数8〜22の直鎖および分岐鎖の
飽和および不飽和脂肪酸、例えば、n−デカン酸、2−
エチルヘキサン酸、オレイン酸、イソステアリン酸など
が挙げられる。該エステルの好ましい配合量は、化粧料
全量に対して0.01−10重量%、好ましくは、0.
1〜5重量%である。配合量が0,01重里%以下では
充分な効果が得られず、また、10重量%以上では逆に
べたつき感が増強されて好ましくない。Examples of the polyhydric alcohol of the liquid polyhydric alcohol fatty acid ester to be incorporated into the cosmetic of the present invention include ethylene glycol, propylene glycol, neopendel glycol, glycerin, diglycerin, sorbitan, etc.
The fatty acids include linear and branched saturated and unsaturated fatty acids having 8 to 22 carbon atoms, such as n-decanoic acid, 2-decanoic acid,
Examples include ethylhexanoic acid, oleic acid, and isostearic acid. The preferred blending amount of the ester is 0.01-10% by weight, preferably 0.01-10% by weight, based on the total amount of the cosmetic.
It is 1 to 5% by weight. If the amount is less than 0.01% by weight, sufficient effects cannot be obtained, and if it is more than 10% by weight, the sticky feeling will be increased, which is not preferable.
さらに、本発明の化粧料には、必要に応じて適当な界面
活性剤、増粘剤、防腐剤、殺菌剤、抗酸化剤、多価アル
コール、香料、色素等をその特性を損なわない範囲で添
加してよい。Furthermore, the cosmetics of the present invention may contain appropriate surfactants, thickeners, preservatives, bactericidal agents, antioxidants, polyhydric alcohols, fragrances, pigments, etc., as necessary, within a range that does not impair its properties. May be added.
−i−春nllハlしh1°本1jトイ))トン−フナ
−プ翻1 :/l−小f−L ふJでき、溶液系、乳
化系、粉末分散系にて化粧水、乳液、クリーム、パック
、ファンデーション等の皮膚用化粧料およびシャンプー
、ヘアートニック、ヘアーリキッド、ヘアートリートメ
ント、ヘアースプレー等の頭髪化粧用等の通常の網形と
することができる。-i-Spring nll Harashi h1° Book 1j Toy)) Ton-funa-pu translation 1 :/l-small f-L FuJ can be used as a solution system, emulsion system, powder dispersion system, lotion, milky lotion, etc. It can be used in the usual net shape for skin cosmetics such as creams, packs, and foundations, and hair cosmetics such as shampoos, hair tonics, hair liquids, hair treatments, and hair sprays.
実施例 。Example .
つぎに実施例および比較例を挙げて本発明をさらに詳し
く説明する。Next, the present invention will be explained in more detail with reference to Examples and Comparative Examples.
実施例1
ヘアートニック
次の処方により、常法に従ってヘアートニックを製造し
た。Example 1 Hair tonic A hair tonic was produced according to the following recipe according to a conventional method.
成分 重量%
20%デューク果皮祖抽出物(エタ
ノール溶液)0.5
ネオペンデルグリコールジ(n−
デカンエート)0.1
エチルアルコール 70.0Q−メン
トール O1香料
0.1精製水
適量実施例2
ヘアートニック
次の処方により、常法に従ってヘアートニックを製造し
た。Ingredients Weight % 20% Duke pericarp extract (ethanol solution) 0.5 Neopendel glycol di(n-decaneate) 0.1 Ethyl alcohol 70.0 Q-menthol O1 fragrance
0.1 purified water
Appropriate amount Example 2 Hair tonic A hair tonic was manufactured according to the following recipe according to a conventional method.
成分 重量%
20%デューク果皮粗抽出物(エタ
ノール溶液)0.5
ネオペンチルグリコールジ(n −
デカノエー’r−)2.5
エヂルアルコール 70.0g−メ
ントール 0.1香料
0.1精製水
a量実施例3
シャンプー
成分 重量%
ランジック酸 1.0グリセリ
ンモノラウレート 2.0アルキル硫酸トリ
エタノールアミン l010プロピレングリコール
5.0ヤシ油脂肪酸ジエタノールアミド
5.0水添レンヂン 3.
0尿素 0.5防腐剤
および香料 微量イオン交換水
適徂以上の成分を約70℃にて均
一に撹拌溶解した後冷却してシャンプーを製造した。Ingredients Weight % 20% Duke pericarp crude extract (ethanol solution) 0.5 Neopentyl glycol di(n-decanoe'r-) 2.5 Edyyl alcohol 70.0g - Menthol 0.1 Flavor
0.1 purified water
A amount Example 3 Shampoo ingredients Weight % Landic acid 1.0 Glycerin monolaurate 2.0 Triethanolamine alkyl sulfate 1010 Propylene glycol
5.0 coconut oil fatty acid diethanolamide
5.0 Hydrogenated Renjin 3.
0 urea 0.5 preservatives and fragrances trace amounts of ion exchange water
A shampoo was prepared by uniformly stirring and dissolving the ingredients in excess of the appropriate amount at about 70° C. and then cooling the mixture.
実施例4
リンス
成分 重量%
成分Aおよび成分Bをそれぞれ約75℃にて均一に溶解
した。ついで、撹拌しながら成分Aを成分Bに加えた後
冷却してリンスを製造した。Example 4 Rinse component Weight % Component A and component B were each uniformly dissolved at about 75°C. Next, component A was added to component B while stirring, and the mixture was cooled to produce a rinse.
実施例5 洗顔クリーム 成分 重量% 成分Aおよび成分Bをそれぞれ約75℃にて溶解した。Example 5 face wash cream Ingredients Weight% Component A and component B were each dissolved at about 75°C.
ついで、同温度にて撹拌しながら成分[3を成分Aに加
えた後冷却して洗顔クリームを製造した。Next, component [3] was added to component A while stirring at the same temperature, and then cooled to produce a facial cleansing cream.
実施例6 コールドクリーム 成分 I% 成分Aおよび成分Bをそれぞれ約75℃にて溶解した。Example 6 cold cream Ingredients I% Component A and component B were each dissolved at about 75°C.
ついで、撹拌しながら成分Bを成分Aに加えた後冷却し
てコールドクリームを製造した。Next, component B was added to component A while stirring, and the mixture was cooled to produce cold cream.
実施例7 モイスヂヤーバツク 成分 重量% 成分Aおよび成分Bをそれぞれ約70℃にて溶解した。Example 7 Moisture bag Ingredients Weight% Component A and component B were each dissolved at about 70°C.
ついで、撹拌しながら成分Aを成分13に力iえた後冷
却してモイスチャーバックを製造した。Next, component A was added to component 13 while stirring, and then cooled to produce a moisture bag.
実施例8
モイスチャークリーム
成分 重量%
[ランジック酸 0.5成分A
および成分Bをそれぞれ約75℃にて均一に溶解した。Example 8 Moisture cream component Weight % [Landic acid 0.5 component A
and component B were each uniformly dissolved at about 75°C.
ついで、撹拌しながら成分Aを成分Bに加えた後冷却し
てモイスチャークリームを製造した。Next, component A was added to component B while stirring, and the mixture was cooled to produce a moisture cream.
実施例9
ヘアートリートメント
成分 重1%
Cランノック酸 l・4成分
Aおよび成分Bをそれぞれ約75℃にて均一に溶解、し
た。ついで、撹拌しながら成分【3を成分Aに加えた後
冷却してヘアートリートメントを製造した。Example 9 Hair Treatment Ingredients 1% by weight C-rannoic acid 1.4 Component A and component B were each uniformly dissolved at about 75°C. Next, component [3] was added to component A while stirring, and the mixture was cooled to produce a hair treatment.
実施例1O
ポマード
成分 重量%
ランジック酸 0.5テトラグ
リセリンモノラウレート 0.2硬化ヒマンflj
50.0木ろう
19.3流動パラフイン
15.0ワセリン
io、。Example 1O Pomade component Weight % Landic acid 0.5 Tetraglycerin monolaurate 0.2 Hardened hemanflj
50.0 Kirou
19.3 Liquid paraffin
15.0 Vaseline
io,.
オリーブ油 5.0以上の
成分を75℃にて溶解した後撹拌しながら冷却してポマ
ードを製造した。Olive oil 5.0 or higher components were dissolved at 75° C. and then cooled with stirring to produce a pomade.
実施例II
ヘアークリーム
成分 重量%
L精製水 R単成分Aお
よび成分Bをそれぞれ約80℃にて均一に溶解した。つ
いで、撹拌しながら成分Aを成分Bに加えた後冷却して
ヘアークリームを製造した。Example II Hair cream component Weight % L Purified water R Single component A and component B were each uniformly dissolved at about 80°C. Next, component A was added to component B while stirring, and the mixture was cooled to produce a hair cream.
実施例12
液状整髪料
成分 重量%
20%デューク果皮粗抽出物(エタ
ノール溶液)5.0
ネオペンチルグリコールジオクタ
ネート、1.0
エタノール 50.0ポリオ
キシプロピレンプチル
エーテル 10.0′ヒアル
ロン酸 0.01香料
0.3精製水
適量以上の成分により、常法に従っ
て液状整髪料を製造した。Example 12 Liquid hair conditioner ingredients Weight % 20% Duke peel crude extract (ethanol solution) 5.0 Neopentyl glycol dioctanate, 1.0 Ethanol 50.0 Polyoxypropylene butyl ether 10.0' Hyaluronic acid 0. 01 fragrance
0.3 Purified water
A liquid hair styling product was prepared using appropriate amounts or more of the ingredients according to a conventional method.
実施例13
化粧水
成分 重量%
ランジック酸ナトリウム 0.lジグリセ
リンジイソステアレート 0.1エチルアルコール
20.0グリセリン
3.0ペンタエリスリトール
2.0ポリオキシエチレン硬化ヒマシ油 0
.5乳酸 0.3谷料
0.1防腐剤
微量精製水
適量以上の成分により、常法に従って
化粧水を製造した。Example 13 Lotion ingredient Weight % Sodium ranzic acid 0. l diglycerin diisostearate 0.1 ethyl alcohol 20.0 glycerin
3.0 Pentaerythritol
2.0 Polyoxyethylene hydrogenated castor oil 0
.. 5 Lactic acid 0.3 Preservatives 0.1 Preservatives
micro purified water
A lotion was prepared using appropriate amounts or more of the ingredients according to a conventional method.
実施例14
乳液
成分 重量%
C30%デコーク果皮祖抽出物(エタ
ノール溶液)2.0
成分Aおよび成分Bをそれぞれ約70℃にて均一に溶解
した。ついで、撹拌しながら成分Aを成分Bに加えた後
冷却し、さらに成分Cを加えて乳液を製造した。Example 14 Emulsion component Weight % C30% Decoke pericarp extract (ethanol solution) 2.0 Component A and component B were each uniformly dissolved at about 70°C. Next, component A was added to component B while stirring, and then cooled, and component C was further added to produce a milky lotion.
゛・実施例15
制汗剤
成分 重量%
Bフロンガス 87.0成分A
を均一に分散し、耐圧缶に入れた後密閉し、成分Bを充
填して制汗剤を製造した。゛・Example 15 Antiperspirant component Weight % B Freon gas 87.0 Component A
was uniformly dispersed, placed in a pressure-resistant can, sealed, and filled with component B to produce an antiperspirant.
実施例16
アフターシェーブローション
成分 重量%
20%デューク果皮粗抽出物(エタ
ノール溶液)1.5
グリセリントリオクタネート 0.3エタノー
ル 40.0ポリオキシエチ
レンセチル
エーテル 0.6ポリオキ
シ工チレンシリコル誘導体 0.1ヒアルロン酸ナト
リウム 0.05香料
0.3精製水
適量以上の成分により、常法に従ってアフター
シェーブローションを製造した。Example 16 Aftershave lotion ingredients Weight % 20% Duke pericarp crude extract (ethanol solution) 1.5 Glycerin trioctanate 0.3 Ethanol 40.0 Polyoxyethylene cetyl ether 0.6 Polyoxyethylene silicone derivative 0.1 Hyaluronic acid Sodium 0.05 Flavoring
0.3 Purified water
An aftershave lotion was prepared according to a conventional method using appropriate amounts or more of the ingredients.
実施例17
0焼け[Lめ化粧料
成分 重量%
成分Aおよび成分Bをそれぞれ約75℃にて均一に溶解
した。ついで、撹拌しながら成分Aを成分Bに加えた後
冷却して日焼は止め化粧料を製造した。Example 17 0 Burnt Cosmetic Component Weight % Component A and component B were each uniformly dissolved at about 75°C. Next, component A was added to component B while stirring, and the mixture was cooled to produce a sunscreen cosmetic.
実施例18
養毛材
成分 重M%
ランジック酸 0.2グリセリ
ントリオクタネート 0.1エタノール
50.0ポリオキシエチレン硬化
ヒマシ油 2,0ピロリドンカルボン酸ナトリウム
1.0塩酸ピリドキシン 0
.1酢酸dQ−α−トコフェロール 0.01
香料 0.3精製水
適量以上の成分を均一
に撹拌溶解して養毛材を製造した。Example 18 Hair nourishing ingredient Weight M% Landic acid 0.2 Glycerin trioctanaate 0.1 Ethanol
50.0 Polyoxyethylene hydrogenated castor oil 2,0 Sodium pyrrolidone carboxylate 1.0 Pyridoxine hydrochloride 0
.. dQ-α-tocopherol 1acetate 0.01
Fragrance 0.3 Purified water A hair nourishing material was produced by uniformly stirring and dissolving an appropriate amount or more of the ingredients.
比較例1
ヘアートニック
次の処方により、常法に従ってヘアートニックを製造し
た。Comparative Example 1 Hair tonic A hair tonic was produced according to the following recipe according to a conventional method.
成分 重量%
9 n01ニー )t …け! ill hh
+I+ 44m / w )rノール溶液)0.5
エチルアルコール 70.0g−メ
ントール 0.1香料
0.l精製水
適量つぎに、前記実施例1および2な
らびに比較例1のへアートニックを30日間、1日に2
回頭皮に塗布し、マツサージさけ、使用感およびフケの
発生を各10名のフケ症男性パネル員に評価させた。結
果を第1表に示す。表中の数値は、該当する評価をした
パネル員の人数である。Ingredients Weight % 9 n01 knee ) t...ke! ill hh
+I+ 44m/w) rNol solution) 0.5 Ethyl alcohol 70.0g-Menthol 0.1 Fragrance
0. l Purified water
Next, apply an appropriate amount of the Hair Artonic of Examples 1 and 2 and Comparative Example 1 twice a day for 30 days.
It was applied to the scalp, and 10 male panelists with dandruff each evaluated the prevention of pine surge, the feeling of use, and the occurrence of dandruff. The results are shown in Table 1. The numbers in the table are the number of panel members who conducted the corresponding evaluation.
第1表
第1表に示したように、液状多価アルコール脂肪酸エス
テルの1種であるネオベンチルグリコールジ(n−デカ
ノエート)を併用することにより、デューク果皮祖抽出
物配合に起因するべたつき感の緩和およびデューク果皮
粗抽出物の皮膚浸透性増加による毛母細胞および頭皮細
胞の活性化に起因する毛髪のしっとり感の付与およびフ
ケ症状の改善に著しい効果が認められた。Table 1 As shown in Table 1, the combined use of neobentyl glycol di(n-decanoate), a type of liquid polyhydric alcohol fatty acid ester, reduces the sticky feeling caused by the combination of Duke pericarp extract. A remarkable effect was observed in alleviating the dandruff symptoms, imparting a moist feeling to the hair, and improving the symptoms of dandruff caused by the activation of hair matrix cells and scalp cells due to the increased skin permeability of the crude extract of Duke fruit peel.
Claims (1)
たはランジウムドメスチカムジャックバーランサの果皮
より得られた粗抽出物、その成分であるランジック酸、
ランジオサイドおよびそれらの誘導体から選ばれる1種
または2種以上および液状多価アルコール脂肪酸エステ
ル類から選ばれる1種または2種以上を配合したことを
特徴とする化粧料。(1) Crude extract obtained from the peel of Randium domesticum jack barduke or Randium domesticum jack barlantha, its component randic acid,
A cosmetic comprising one or more selected from landioside and derivatives thereof and one or more selected from liquid polyhydric alcohol fatty acid esters.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62046545A JPS63211209A (en) | 1987-02-26 | 1987-02-26 | Cosmetic |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62046545A JPS63211209A (en) | 1987-02-26 | 1987-02-26 | Cosmetic |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS63211209A true JPS63211209A (en) | 1988-09-02 |
Family
ID=12750277
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62046545A Pending JPS63211209A (en) | 1987-02-26 | 1987-02-26 | Cosmetic |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS63211209A (en) |
-
1987
- 1987-02-26 JP JP62046545A patent/JPS63211209A/en active Pending
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