JPS63192793A - ４′−デメチル−エピポドフイロトキシン誘導体の新規エステル - Google Patents

４′−デメチル−エピポドフイロトキシン誘導体の新規エステル

Info

Publication number
JPS63192793A
JPS63192793A JP62024495A JP2449587A JPS63192793A JP S63192793 A JPS63192793 A JP S63192793A JP 62024495 A JP62024495 A JP 62024495A JP 2449587 A JP2449587 A JP 2449587A JP S63192793 A JPS63192793 A JP S63192793A
Authority
JP
Japan
Prior art keywords
demethyl
water
epipodophyllotoxin
ethylidene
added
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP62024495A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0532399B2 (enrdf_load_stackoverflow
Inventor
Hideo Sugimura
杉村　秀夫
Tetsuyuki Saino
哲之 才野
Kazuya Okamoto
一也 岡本
Kiyohiro Nishikawa
西川　清宏
Katsutoshi Takahashi
克俊 高橋
Rinzo Nishizawa
西沢　林蔵
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Kayaku Co Ltd
Original Assignee
Nippon Kayaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Co Ltd filed Critical Nippon Kayaku Co Ltd
Priority to JP62024495A priority Critical patent/JPS63192793A/ja
Publication of JPS63192793A publication Critical patent/JPS63192793A/ja
Publication of JPH0532399B2 publication Critical patent/JPH0532399B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP62024495A 1987-02-06 1987-02-06 ４′−デメチル−エピポドフイロトキシン誘導体の新規エステル Granted JPS63192793A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62024495A JPS63192793A (ja) 1987-02-06 1987-02-06 ４′−デメチル−エピポドフイロトキシン誘導体の新規エステル

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62024495A JPS63192793A (ja) 1987-02-06 1987-02-06 ４′−デメチル−エピポドフイロトキシン誘導体の新規エステル

Publications (2)

Publication Number Publication Date
JPS63192793A true JPS63192793A (ja) 1988-08-10
JPH0532399B2 JPH0532399B2 (enrdf_load_stackoverflow) 1993-05-14

Family

ID=12139757

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62024495A Granted JPS63192793A (ja) 1987-02-06 1987-02-06 ４′−デメチル−エピポドフイロトキシン誘導体の新規エステル

Country Status (1)

Country Link
JP (1) JPS63192793A (enrdf_load_stackoverflow)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01100188A (ja) * 1987-08-04 1989-04-18 Bristol Myers Co エピポドフイロトキシングルコシド４′−リン酸誘導体
JPH02178299A (ja) * 1988-10-31 1990-07-11 Bristol Myers Squibb Co エピポドフィロトキシングルコシドの糖ホスフェート類及びスルホネート類
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
US5066645A (en) * 1989-09-01 1991-11-19 Bristol-Myers Company Epipodophyllotoxin altroside derivatives
US5270196A (en) * 1989-10-20 1993-12-14 Bristol-Myers Squibb Company Arylsulfatase from streptomyces
US5606039A (en) * 1992-04-24 1997-02-25 Nippon Kayaku Kabushiki Kaisha Etoposide phosphate and preparative intermediates
US6475486B1 (en) 1990-10-18 2002-11-05 Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
US6610299B1 (en) 1989-10-19 2003-08-26 Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
US7241595B2 (en) 1989-10-20 2007-07-10 Sanofi-Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3039793B1 (fr) 2015-08-05 2017-09-15 Expliseat Siege deformable pour vehicule

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE35524E (en) * 1987-08-04 1997-06-03 Bristol-Myers Squibb Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
US5041424A (en) * 1987-08-04 1991-08-20 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
JPH01100188A (ja) * 1987-08-04 1989-04-18 Bristol Myers Co エピポドフイロトキシングルコシド４′−リン酸誘導体
JPH02178299A (ja) * 1988-10-31 1990-07-11 Bristol Myers Squibb Co エピポドフィロトキシングルコシドの糖ホスフェート類及びスルホネート類
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
US5066645A (en) * 1989-09-01 1991-11-19 Bristol-Myers Company Epipodophyllotoxin altroside derivatives
US6610299B1 (en) 1989-10-19 2003-08-26 Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
US5270196A (en) * 1989-10-20 1993-12-14 Bristol-Myers Squibb Company Arylsulfatase from streptomyces
US7241595B2 (en) 1989-10-20 2007-07-10 Sanofi-Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
US6475486B1 (en) 1990-10-18 2002-11-05 Aventis Pharma Deutschland Gmbh Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates
US5637680A (en) * 1992-04-24 1997-06-10 Nippon Kayaku Kabushiki Kaisha Process for the preparation of etoposide phosphate and intermediate thereof
US5606039A (en) * 1992-04-24 1997-02-25 Nippon Kayaku Kabushiki Kaisha Etoposide phosphate and preparative intermediates

Also Published As

Publication number Publication date
JPH0532399B2 (enrdf_load_stackoverflow) 1993-05-14

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