JPS6313985B2 - - Google Patents

Info

Publication number
JPS6313985B2
JPS6313985B2 JP59222452A JP22245284A JPS6313985B2 JP S6313985 B2 JPS6313985 B2 JP S6313985B2 JP 59222452 A JP59222452 A JP 59222452A JP 22245284 A JP22245284 A JP 22245284A JP S6313985 B2 JPS6313985 B2 JP S6313985B2
Authority
JP
Japan
Prior art keywords
compound
acetic acid
indole
inflammatory
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP59222452A
Other languages
English (en)
Japanese (ja)
Other versions
JPS61100565A (ja
Inventor
Tsutomu Fukaya
Yoichiro Naito
Shuichi Hanada
Masahiro Watanabe
Kazumasa Yokoyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GC Biopharma Corp
Original Assignee
Green Cross Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Korea filed Critical Green Cross Corp Korea
Priority to JP59222452A priority Critical patent/JPS61100565A/ja
Priority to AU48573/85A priority patent/AU576390B2/en
Priority to CA000493174A priority patent/CA1287625C/en
Priority to ZA857987A priority patent/ZA857987B/xx
Priority to AT85113334T priority patent/ATE41867T1/de
Priority to EP85113334A priority patent/EP0179428B1/en
Priority to DE8585113334T priority patent/DE3569196D1/de
Priority to KR1019850007758A priority patent/KR860003218A/ko
Priority to ES548067A priority patent/ES8703423A1/es
Publication of JPS61100565A publication Critical patent/JPS61100565A/ja
Priority to US07/042,924 priority patent/US4868201A/en
Publication of JPS6313985B2 publication Critical patent/JPS6313985B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP59222452A 1984-10-22 1984-10-22 インド−ル酢酸誘導体 Granted JPS61100565A (ja)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP59222452A JPS61100565A (ja) 1984-10-22 1984-10-22 インド−ル酢酸誘導体
AU48573/85A AU576390B2 (en) 1984-10-22 1985-10-14 Indoleacetic acid derivative for use as antiinflammatory and analgesic agents
CA000493174A CA1287625C (en) 1984-10-22 1985-10-17 Indoleacetic acid derivative
ZA857987A ZA857987B (en) 1984-10-22 1985-10-17 Indoleacetic acid derivative
EP85113334A EP0179428B1 (en) 1984-10-22 1985-10-21 Indoleacetic acid derivative and a pharmaceutical preparation
AT85113334T ATE41867T1 (de) 1984-10-22 1985-10-21 Indolessigsaeurederivat und pharmazeutisches praeparat.
DE8585113334T DE3569196D1 (en) 1984-10-22 1985-10-21 Indoleacetic acid derivative and a pharmaceutical preparation
KR1019850007758A KR860003218A (ko) 1984-10-22 1985-10-21 인돌아세트산 유도체 및 그 염의 제조방법
ES548067A ES8703423A1 (es) 1984-10-22 1985-10-21 Un procedimiento para producir un derivado de acido indola- cetico
US07/042,924 US4868201A (en) 1984-10-22 1987-04-27 Indoleacetic acid derivatives used as anti-inflammatories

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59222452A JPS61100565A (ja) 1984-10-22 1984-10-22 インド−ル酢酸誘導体

Publications (2)

Publication Number Publication Date
JPS61100565A JPS61100565A (ja) 1986-05-19
JPS6313985B2 true JPS6313985B2 (en, 2012) 1988-03-29

Family

ID=16782628

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59222452A Granted JPS61100565A (ja) 1984-10-22 1984-10-22 インド−ル酢酸誘導体

Country Status (10)

Country Link
US (1) US4868201A (en, 2012)
EP (1) EP0179428B1 (en, 2012)
JP (1) JPS61100565A (en, 2012)
KR (1) KR860003218A (en, 2012)
AT (1) ATE41867T1 (en, 2012)
AU (1) AU576390B2 (en, 2012)
CA (1) CA1287625C (en, 2012)
DE (1) DE3569196D1 (en, 2012)
ES (1) ES8703423A1 (en, 2012)
ZA (1) ZA857987B (en, 2012)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1224546B (it) * 1988-09-29 1990-10-04 Polifarma Spa Utilizzatore farmaceutica di acido 3 -indolpiruvico come agente inibitore di patologie degenerative
CA2072360A1 (en) * 1989-12-26 1991-06-27 Abraham J. Domb Prodrug anhydride compositions
US5222109A (en) * 1990-12-28 1993-06-22 Ibm Corporation Endurance management for solid state files
US5436265A (en) * 1993-11-12 1995-07-25 Merck Frosst Canada, Inc. 1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents
GB9716657D0 (en) * 1997-08-07 1997-10-15 Zeneca Ltd Chemical compounds
US6345001B1 (en) 2000-09-14 2002-02-05 Sandisk Corporation Compressed event counting technique and application to a flash memory system
US7113432B2 (en) 2000-09-14 2006-09-26 Sandisk Corporation Compressed event counting technique and application to a flash memory system

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3468907A (en) * 1967-04-10 1969-09-23 Schering Corp Glyceryl esters of alpha-(1-aroyl-3-indolyl)alkanoic acids
US3966956A (en) * 1972-07-14 1976-06-29 Troponwerke Dinklage & Company [1-(P-Chlorobenzoyl)-5-methoxy-2-methyl-3-indole]acetoxyacetic acid and salts in treating inflammation
US4104278A (en) * 1972-11-25 1978-08-01 Troponwerke Dinklage & Co. Process for the production of compounds with antiphlogistic activity
DE2740852A1 (de) * 1977-09-10 1979-03-29 Troponwerke Gmbh & Co Kg Basische 1-acylindol-3-acetocyessigsaeureester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3206888A1 (de) * 1982-02-26 1983-09-15 Troponwerke GmbH & Co KG, 5000 Köln Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indolacetoxyessigsaeure

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS=1974 *

Also Published As

Publication number Publication date
US4868201A (en) 1989-09-19
ZA857987B (en) 1987-06-24
EP0179428B1 (en) 1989-04-05
ATE41867T1 (de) 1989-04-15
CA1287625C (en) 1991-08-13
DE3569196D1 (en) 1989-05-11
AU4857385A (en) 1986-05-01
JPS61100565A (ja) 1986-05-19
ES8703423A1 (es) 1987-02-16
KR860003218A (ko) 1986-05-21
ES548067A0 (es) 1987-02-16
EP0179428A3 (en) 1986-07-16
EP0179428A2 (en) 1986-04-30
AU576390B2 (en) 1988-08-25

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