JPS6239564A - α−ベンジリデン−γ−ブチロラクトンまたはγ−ブチロラクタム誘導体 - Google Patents

α−ベンジリデン−γ−ブチロラクトンまたはγ−ブチロラクタム誘導体

Info

Publication number
JPS6239564A
JPS6239564A JP17835785A JP17835785A JPS6239564A JP S6239564 A JPS6239564 A JP S6239564A JP 17835785 A JP17835785 A JP 17835785A JP 17835785 A JP17835785 A JP 17835785A JP S6239564 A JPS6239564 A JP S6239564A
Authority
JP
Japan
Prior art keywords
benzylidene
formula
butyrolactone
represented
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP17835785A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0523262B2 (index.php
Inventor
Tadayoshi Shiraishi
忠義 白石
Yoshio Shimada
嶋田　善夫
Yoshihide Fuse
佳秀 布施
Naohiro Imai
直博 今井
Katsuji Yamashita
山下　勝治
Toshiaki Yamashita
山下　俊章
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Priority to JP17835785A priority Critical patent/JPS6239564A/ja
Publication of JPS6239564A publication Critical patent/JPS6239564A/ja
Publication of JPH0523262B2 publication Critical patent/JPH0523262B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Furan Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
JP17835785A 1985-08-13 1985-08-13 α−ベンジリデン−γ−ブチロラクトンまたはγ−ブチロラクタム誘導体 Granted JPS6239564A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP17835785A JPS6239564A (ja) 1985-08-13 1985-08-13 α−ベンジリデン−γ−ブチロラクトンまたはγ−ブチロラクタム誘導体

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17835785A JPS6239564A (ja) 1985-08-13 1985-08-13 α−ベンジリデン−γ−ブチロラクトンまたはγ−ブチロラクタム誘導体

Publications (2)

Publication Number Publication Date
JPS6239564A true JPS6239564A (ja) 1987-02-20
JPH0523262B2 JPH0523262B2 (index.php) 1993-04-02

Family

ID=16047074

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17835785A Granted JPS6239564A (ja) 1985-08-13 1985-08-13 α−ベンジリデン−γ−ブチロラクトンまたはγ−ブチロラクタム誘導体

Country Status (1)

Country Link
JP (1) JPS6239564A (index.php)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792783A (en) * 1995-06-07 1998-08-11 Sugen, Inc. 3-heteroaryl-2-indolinone compounds for the treatment of disease
US6451838B1 (en) 2000-05-24 2002-09-17 Pharmacia & Upjohn Company 1-(pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US6531502B1 (en) 1998-01-21 2003-03-11 Sugen, Inc. 3-Methylidenyl-2-indolinone modulators of protein kinase
US6569868B2 (en) 1998-04-16 2003-05-27 Sugen, Inc. 2-indolinone derivatives as modulators of protein kinase activity
US6599902B2 (en) 2001-05-30 2003-07-29 Sugen, Inc. 5-aralkysufonyl-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives as kinase inhibitors
US6706709B2 (en) 2000-06-02 2004-03-16 Sugen, Inc. Indolinone derivatives as protein kinase/phosphatase inhibitors
WO2004069998A3 (en) * 2003-02-03 2004-11-18 Arrow Therapeutics Ltd Oxindole derivatives as antimicrobial agents
US6906093B2 (en) 1995-06-07 2005-06-14 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
US7125905B2 (en) 2000-02-15 2006-10-24 Agouron Pharmaceuticals, Inc. Pyrrole substituted 2-indolinone protein kinase inhibitors
US7179910B2 (en) 2001-02-15 2007-02-20 Agouron Pharmaceuticals, Inc. 3-(4-amidopyrrol-2-ylmethlidene)-2-indolinone derivatives as protein kinase inhibitors
US7202265B2 (en) 1997-08-20 2007-04-10 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6225335B1 (en) 1995-06-07 2001-05-01 Sugen, Inc. 3-(4′-bromobenzylindenyl)-2-indolinone and analogues thereof for the treatment of disease
US6906093B2 (en) 1995-06-07 2005-06-14 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
US5880141A (en) * 1995-06-07 1999-03-09 Sugen, Inc. Benzylidene-Z-indoline compounds for the treatment of disease
US5883116A (en) * 1995-06-07 1999-03-16 Sugen, Inc. 3-(2'-alkoxybenzylidenyl)-2-indolinone and analogues thereof for the treatment of disease
US5883113A (en) * 1995-06-07 1999-03-16 Sugen, Inc. 3-(4'-Bromobenzylindenyl)-2-indolinone and analogues thereof for the treatment of disease
US5886020A (en) * 1995-06-07 1999-03-23 Sugen, Inc. 3-(4'-dimethylaminobenzylidenyl)-2-indolinone and analogues thereof for the treatment of disease
US5834504A (en) * 1995-06-07 1998-11-10 Sugen, Inc. 3-(2'-halobenzylidenyl)-2-indolinone compounds for the treatment of disease
US6469032B2 (en) 1995-06-07 2002-10-22 Sugen, Inc. 3-(4′-bromobenzylindenyl)-2-indolinone and analogues thereof for the treatment of disease
US5792783A (en) * 1995-06-07 1998-08-11 Sugen, Inc. 3-heteroaryl-2-indolinone compounds for the treatment of disease
US7202265B2 (en) 1997-08-20 2007-04-10 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
US6531502B1 (en) 1998-01-21 2003-03-11 Sugen, Inc. 3-Methylidenyl-2-indolinone modulators of protein kinase
US6569868B2 (en) 1998-04-16 2003-05-27 Sugen, Inc. 2-indolinone derivatives as modulators of protein kinase activity
US6855730B2 (en) 1998-08-05 2005-02-15 Sugen, Inc. 3-methylidenyl-2-indolinone modulators of protein kinase
US7125905B2 (en) 2000-02-15 2006-10-24 Agouron Pharmaceuticals, Inc. Pyrrole substituted 2-indolinone protein kinase inhibitors
US7572924B2 (en) 2000-02-15 2009-08-11 Sugen, Inc. Pyrrole substituted 2-indolinone protein kinase inhibitors
US6710067B2 (en) 2000-05-24 2004-03-23 Sugen Incorporated Mannich base prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US7112603B2 (en) 2000-05-24 2006-09-26 Agouron Pharmaceuticals, Inc. Prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US6716870B2 (en) 2000-05-24 2004-04-06 Sugen, Inc. Prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US6451838B1 (en) 2000-05-24 2002-09-17 Pharmacia & Upjohn Company 1-(pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US7008943B2 (en) 2000-05-24 2006-03-07 Pharmacia & Upjohn Company 1-(Pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US7053113B2 (en) 2000-05-24 2006-05-30 Sugen, Inc. Mannich base prodrugs of 3-(pyrrol-2-yl-methylidene)-2-indolinone derivatives
US6482848B2 (en) 2000-05-24 2002-11-19 Sugen Incorporated Prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
US7071332B2 (en) 2000-06-02 2006-07-04 Sugen, Inc. Indolinone derivatives as protein kinase/phosphatase inhibitors
US6706709B2 (en) 2000-06-02 2004-03-16 Sugen, Inc. Indolinone derivatives as protein kinase/phosphatase inhibitors
US7179910B2 (en) 2001-02-15 2007-02-20 Agouron Pharmaceuticals, Inc. 3-(4-amidopyrrol-2-ylmethlidene)-2-indolinone derivatives as protein kinase inhibitors
US7256189B2 (en) 2001-02-15 2007-08-14 Sugen, Inc. 3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone der derivatives as protein kinase inhibitors
US7582756B2 (en) 2001-02-15 2009-09-01 Sugen, Inc. 3-(4-amidopyrrol-2-ylmethylidene)-2-indolinone derivatives as protein kinase inhibitors
US6599902B2 (en) 2001-05-30 2003-07-29 Sugen, Inc. 5-aralkysufonyl-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives as kinase inhibitors
WO2004069998A3 (en) * 2003-02-03 2004-11-18 Arrow Therapeutics Ltd Oxindole derivatives as antimicrobial agents

Also Published As

Publication number Publication date
JPH0523262B2 (index.php) 1993-04-02

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