JPS62224356A - 生体硬組織補修材料およびその製造法 - Google Patents
生体硬組織補修材料およびその製造法Info
- Publication number
- JPS62224356A JPS62224356A JP61068202A JP6820286A JPS62224356A JP S62224356 A JPS62224356 A JP S62224356A JP 61068202 A JP61068202 A JP 61068202A JP 6820286 A JP6820286 A JP 6820286A JP S62224356 A JPS62224356 A JP S62224356A
- Authority
- JP
- Japan
- Prior art keywords
- hard tissue
- synthetic hydroxyapatite
- bone
- repair material
- hydroxyapatite
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000463 material Substances 0.000 title claims description 34
- 238000004519 manufacturing process Methods 0.000 title claims description 6
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 33
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 32
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical group OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 11
- 239000011247 coating layer Substances 0.000 claims description 11
- 239000000203 mixture Substances 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 7
- 230000017423 tissue regeneration Effects 0.000 claims description 7
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims description 3
- 229910001424 calcium ion Inorganic materials 0.000 claims description 3
- 210000000988 bone and bone Anatomy 0.000 description 22
- 230000008439 repair process Effects 0.000 description 19
- 238000000605 extraction Methods 0.000 description 11
- 239000002245 particle Substances 0.000 description 11
- 239000000047 product Substances 0.000 description 11
- 210000001519 tissue Anatomy 0.000 description 9
- 239000000126 substance Substances 0.000 description 7
- 239000012620 biological material Substances 0.000 description 6
- 230000007547 defect Effects 0.000 description 6
- 238000002441 X-ray diffraction Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 210000001124 body fluid Anatomy 0.000 description 4
- 239000010839 body fluid Substances 0.000 description 4
- 239000000919 ceramic Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 238000000465 moulding Methods 0.000 description 4
- 210000000963 osteoblast Anatomy 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 230000004069 differentiation Effects 0.000 description 3
- 238000010304 firing Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 229910052586 apatite Inorganic materials 0.000 description 2
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 2
- 239000000920 calcium hydroxide Substances 0.000 description 2
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 2
- 238000000748 compression moulding Methods 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 210000002540 macrophage Anatomy 0.000 description 2
- 230000011164 ossification Effects 0.000 description 2
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 238000001308 synthesis method Methods 0.000 description 2
- 206010003694 Atrophy Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000017234 Bone cyst Diseases 0.000 description 1
- 208000018084 Bone neoplasm Diseases 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 208000005156 Dehydration Diseases 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 241000700157 Rattus norvegicus Species 0.000 description 1
- 230000000735 allogeneic effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000007900 aqueous suspension Substances 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 210000003464 cuspid Anatomy 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000001027 hydrothermal synthesis Methods 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 210000001616 monocyte Anatomy 0.000 description 1
- 210000000066 myeloid cell Anatomy 0.000 description 1
- 230000004072 osteoblast differentiation Effects 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 238000005245 sintering Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61068202A JPS62224356A (ja) | 1986-03-26 | 1986-03-26 | 生体硬組織補修材料およびその製造法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61068202A JPS62224356A (ja) | 1986-03-26 | 1986-03-26 | 生体硬組織補修材料およびその製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62224356A true JPS62224356A (ja) | 1987-10-02 |
| JPH0139786B2 JPH0139786B2 (enrdf_load_stackoverflow) | 1989-08-23 |
Family
ID=13366971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61068202A Granted JPS62224356A (ja) | 1986-03-26 | 1986-03-26 | 生体硬組織補修材料およびその製造法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS62224356A (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01158965A (ja) * | 1987-12-16 | 1989-06-22 | Tokuyama Soda Co Ltd | 硬化性組成物 |
| JPH03272769A (ja) * | 1990-03-23 | 1991-12-04 | Mitsubishi Materials Corp | 骨空隙部及び骨吸収部充填用造粒物 |
| JP2001502215A (ja) * | 1996-10-16 | 2001-02-20 | エテックス コーポレイション | 不完全結晶性カルシウムホスフェートの製造法及びその使用法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6040298A (ja) * | 1983-05-05 | 1985-03-02 | ストレイチャン ヘンシャウ マシーナリー リミティド | 印刷ロ−ル用取外し自在スリ−ブ |
| JPS6117409A (ja) * | 1984-07-02 | 1986-01-25 | Meishin Toryo Kk | 非晶質リン酸カルシウムの製法およびこれを主成分とする生体適応性組成物 |
-
1986
- 1986-03-26 JP JP61068202A patent/JPS62224356A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6040298A (ja) * | 1983-05-05 | 1985-03-02 | ストレイチャン ヘンシャウ マシーナリー リミティド | 印刷ロ−ル用取外し自在スリ−ブ |
| JPS6117409A (ja) * | 1984-07-02 | 1986-01-25 | Meishin Toryo Kk | 非晶質リン酸カルシウムの製法およびこれを主成分とする生体適応性組成物 |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01158965A (ja) * | 1987-12-16 | 1989-06-22 | Tokuyama Soda Co Ltd | 硬化性組成物 |
| JPH03272769A (ja) * | 1990-03-23 | 1991-12-04 | Mitsubishi Materials Corp | 骨空隙部及び骨吸収部充填用造粒物 |
| JP2001502215A (ja) * | 1996-10-16 | 2001-02-20 | エテックス コーポレイション | 不完全結晶性カルシウムホスフェートの製造法及びその使用法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0139786B2 (enrdf_load_stackoverflow) | 1989-08-23 |
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