JPS6215557B2 - - Google Patents
Info
- Publication number
- JPS6215557B2 JPS6215557B2 JP52121857A JP12185777A JPS6215557B2 JP S6215557 B2 JPS6215557 B2 JP S6215557B2 JP 52121857 A JP52121857 A JP 52121857A JP 12185777 A JP12185777 A JP 12185777A JP S6215557 B2 JPS6215557 B2 JP S6215557B2
- Authority
- JP
- Japan
- Prior art keywords
- antibiotic
- bacteria
- culture
- solution
- sodium salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- 238000009825 accumulation Methods 0.000 description 1
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- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 1
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- 229910052742 iron Inorganic materials 0.000 description 1
- FMKOJHQHASLBPH-UHFFFAOYSA-N isopropyl iodide Chemical compound CC(C)I FMKOJHQHASLBPH-UHFFFAOYSA-N 0.000 description 1
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- 239000006877 oatmeal agar Substances 0.000 description 1
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- 238000007911 parenteral administration Methods 0.000 description 1
- 150000002960 penicillins Chemical class 0.000 description 1
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- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- LWIHDJKSTIGBAC-UHFFFAOYSA-K potassium phosphate Substances [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 1
- OVARTBFNCCXQKS-UHFFFAOYSA-N propan-2-one;hydrate Chemical compound O.CC(C)=O OVARTBFNCCXQKS-UHFFFAOYSA-N 0.000 description 1
- 229940007042 proteus vulgaris Drugs 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 235000020183 skimmed milk Nutrition 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 235000011121 sodium hydroxide Nutrition 0.000 description 1
- RSIJVJUOQBWMIM-UHFFFAOYSA-L sodium sulfate decahydrate Chemical class O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[O-]S([O-])(=O)=O RSIJVJUOQBWMIM-UHFFFAOYSA-L 0.000 description 1
- OIKQIJBPCDCDDL-ROLPUNSJSA-M sodium;(5s,6s)-3-(2-acetamidoethylsulfanyl)-7-oxo-6-propan-2-yl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate Chemical compound [Na+].C1C(SCCNC(C)=O)=C(C([O-])=O)N2C(=O)[C@@H](C(C)C)[C@@H]21 OIKQIJBPCDCDDL-ROLPUNSJSA-M 0.000 description 1
- HLWRUJAIJJEZDL-UHFFFAOYSA-M sodium;2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetate Chemical compound [Na+].OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC([O-])=O HLWRUJAIJJEZDL-UHFFFAOYSA-M 0.000 description 1
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- 239000008223 sterile water Substances 0.000 description 1
- 239000008227 sterile water for injection Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
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- 238000012546 transfer Methods 0.000 description 1
- JBWKIWSBJXDJDT-UHFFFAOYSA-N triphenylmethyl chloride Chemical compound C=1C=CC=CC=1C(C=1C=CC=CC=1)(Cl)C1=CC=CC=C1 JBWKIWSBJXDJDT-UHFFFAOYSA-N 0.000 description 1
- 239000012137 tryptone Substances 0.000 description 1
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- 229940005605 valeric acid Drugs 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12185777A JPS5459295A (en) | 1977-10-13 | 1977-10-13 | Antibiotic ps-6, its derivative and their preparation |
| DE7878100993T DE2861413D1 (en) | 1977-10-13 | 1978-09-26 | Thienamycin related antibiotics ps-6 and ps-7, process for their production and compositions containing them |
| EP78100993A EP0001567B1 (en) | 1977-10-13 | 1978-09-26 | Thienamycin related antibiotics ps-6 and ps-7, process for their production and compositions containing them |
| YU235178A YU235178A (en) | 1977-10-13 | 1978-10-06 | Process for producing new antibiotics of a betta-lactamaseinhibiting activity |
| US05/949,854 US4368203A (en) | 1977-10-13 | 1978-10-10 | Antibiotics and derivatives thereof having β-lactamase inhibitory activity and production thereof |
| SU782673547A SU1039446A3 (ru) | 1977-10-13 | 1978-10-12 | Способ получени антибиотического комплекса |
| DK454378A DK145382C (da) | 1977-10-13 | 1978-10-12 | Fremgangsmaade til fremstilling af beta-lactamantibiotika kaldet ps-6 og ps-7 eller salte eller estere deraf |
| HU78SA3138A HU179788B (en) | 1977-10-13 | 1978-10-12 | Process for preparing new carbopenem derivatives |
| CA313,287A CA1113872A (en) | 1977-10-13 | 1978-10-12 | ANTIBIOTICS AND DERIVATIVES THEREOF HAVING .beta.-LACTAMASE INHIBITORY ACTIVITY AND PRODUCTION THEREOF |
| IT28782/78A IT1099738B (it) | 1977-10-13 | 1978-10-13 | Antibiotici,loro preparazione e loro impiego come prodotti antimicrobici |
| YU2151/82A YU42049B (en) | 1977-10-13 | 1982-09-27 | Process for producing derivatives of new antibiotics of a beta lactamase inhibiting activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12185777A JPS5459295A (en) | 1977-10-13 | 1977-10-13 | Antibiotic ps-6, its derivative and their preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5459295A JPS5459295A (en) | 1979-05-12 |
| JPS6215557B2 true JPS6215557B2 (enrdf_load_stackoverflow) | 1987-04-08 |
Family
ID=14821641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12185777A Granted JPS5459295A (en) | 1977-10-13 | 1977-10-13 | Antibiotic ps-6, its derivative and their preparation |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5459295A (enrdf_load_stackoverflow) |
-
1977
- 1977-10-13 JP JP12185777A patent/JPS5459295A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5459295A (en) | 1979-05-12 |
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