JPS62124441A - 流動細胞測定装置 - Google Patents

流動細胞測定装置

Info

Publication number
JPS62124441A
JPS62124441A JP61138044A JP13804486A JPS62124441A JP S62124441 A JPS62124441 A JP S62124441A JP 61138044 A JP61138044 A JP 61138044A JP 13804486 A JP13804486 A JP 13804486A JP S62124441 A JPS62124441 A JP S62124441A
Authority
JP
Japan
Prior art keywords
light
light beam
cells
particles
flow cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP61138044A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0544622B2 (en, 2012
Inventor
ハワード・エル・ノース・ジュニアー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of JPS62124441A publication Critical patent/JPS62124441A/ja
Publication of JPH0544622B2 publication Critical patent/JPH0544622B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1452—Adjustment of focus; Alignment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP61138044A 1985-07-29 1986-06-13 流動細胞測定装置 Granted JPS62124441A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US760205 1985-07-29
US06/760,205 US4989977A (en) 1985-07-29 1985-07-29 Flow cytometry apparatus with improved light beam adjustment

Publications (2)

Publication Number Publication Date
JPS62124441A true JPS62124441A (ja) 1987-06-05
JPH0544622B2 JPH0544622B2 (en, 2012) 1993-07-06

Family

ID=25058424

Family Applications (1)

Application Number Title Priority Date Filing Date
JP61138044A Granted JPS62124441A (ja) 1985-07-29 1986-06-13 流動細胞測定装置

Country Status (5)

Country Link
US (1) US4989977A (en, 2012)
EP (1) EP0210343B1 (en, 2012)
JP (1) JPS62124441A (en, 2012)
DE (1) DE3677554D1 (en, 2012)
MY (1) MY102913A (en, 2012)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09508703A (ja) * 1994-08-01 1997-09-02 アボツト・ラボラトリーズ フローサイトメトリック血液細胞分析器用の擬似テレセントリック光学設計
JP2004109010A (ja) * 2002-09-19 2004-04-08 Otsuka Denshi Co Ltd 散乱光測定装置

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JPS63307332A (ja) * 1987-06-08 1988-12-15 Hitachi Ltd 光計測式生体細胞分析装置
US5224058A (en) * 1990-05-01 1993-06-29 Becton, Dickinson And Company Method for data transformation
IL101522A (en) * 1992-04-08 1997-09-30 Combact Imaging Systems Ltd Detection of microorganisms in a sample and determination of the sensitivity of microorganisms to antibiotics
JPH05340865A (ja) * 1992-06-09 1993-12-24 Canon Inc 測定装置
US5812419A (en) * 1994-08-01 1998-09-22 Abbott Laboratories Fully automated analysis method with optical system for blood cell analyzer
US5656499A (en) * 1994-08-01 1997-08-12 Abbott Laboratories Method for performing automated hematology and cytometry analysis
US5891734A (en) * 1994-08-01 1999-04-06 Abbott Laboratories Method for performing automated analysis
US5631165A (en) * 1994-08-01 1997-05-20 Abbott Laboratories Method for performing automated hematology and cytometry analysis
US5831730A (en) * 1996-12-06 1998-11-03 United Sciences, Inc. Method for monitoring particulates using beam-steered solid-state light source
EP1017987B1 (en) 1997-01-31 2005-06-15 The Horticulture And Food Research Institute Of New Zealand Limited Optical apparatus and method
DE19723999B4 (de) * 1997-06-06 2008-04-10 Schwartz, Margit Vorrichtung zur Messung von Partikelabmessungen in Fluiden
DE19755589C2 (de) * 1997-12-15 2002-11-07 Fraunhofer Ges Forschung Vorrichtung für dreidimensionale Kreuzkorrelationstechnik und Verfahren zur Durchführung der Justage von Detektionsoptiken zur Messung von Kreuzkorrelationsfunktionen in flüssigen Medien
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6071689A (en) * 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US7498164B2 (en) * 1998-05-16 2009-03-03 Applied Biosystems, Llc Instrument for monitoring nucleic acid sequence amplification reaction
JP2003524754A (ja) 1998-05-16 2003-08-19 ピーイー コーポレイション （エヌワイ） Ｄｎａのポリメラーゼ連鎖反応をモニタする装置
US6818437B1 (en) 1998-05-16 2004-11-16 Applera Corporation Instrument for monitoring polymerase chain reaction of DNA
US7208265B1 (en) * 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
WO2001040764A2 (en) * 1999-12-01 2001-06-07 Dubelaar Research Instruments Engineering Apparatus for the detection of particles
US6809804B1 (en) 2000-05-11 2004-10-26 Becton, Dickinson And Company System and method for providing improved event reading and data processing capabilities in a flow cytometer
US20040031071A1 (en) * 2000-10-05 2004-02-12 Xy, Inc. System of hysteroscopic insemination of mares
CA2468774C (en) 2000-11-29 2015-06-30 George E. Seidel System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en) * 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US7280207B2 (en) 2001-07-25 2007-10-09 Applera Corporation Time-delay integration in a flow cytometry system
JP4570565B2 (ja) 2002-07-15 2010-10-27 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム ペリプラズム発現によるコンビナトリアルタンパク質ライブラリーのスクリーニング
BRPI0312843B1 (pt) * 2002-07-22 2019-12-03 Xy Inc método para separar células espermáticas
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
CN1674780A (zh) * 2002-08-01 2005-09-28 Xy公司 低压精子分离系统
WO2004017041A2 (en) * 2002-08-15 2004-02-26 Xy, Inc. High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
CN102830053A (zh) 2003-03-28 2012-12-19 英格朗公司 用于分拣颗粒和提供性别分拣的动物精子的设备、方法和程序
WO2004104178A2 (en) * 2003-05-15 2004-12-02 Xy, Inc. Efficient haploid cell sorting for flow cytometer systems
MXPA06011344A (es) 2004-03-29 2006-12-15 Monsanto Technology Llc Suspensiones de espermatozoides para separar en poblaciones enriquecidas con cromosomas x o y.
MX2007000888A (es) 2004-07-22 2007-04-02 Monsanto Technology Llc Procedimiento para enriquecer una poblacion de celulas de esperma.
US7110192B2 (en) * 2005-01-12 2006-09-19 Dako Denmark A/S System and method for a composite lens for a flow cytometer
ATE555128T1 (de) 2006-11-30 2012-05-15 Res Dev Foundation Verbesserte immunglobulin-bibliotheken
CA2685675C (en) 2007-05-01 2016-02-16 Research Development Foundation Immunoglobulin fc libraries
WO2009006422A1 (en) 2007-06-29 2009-01-08 Stem Cell Products, Inc. Automated method and apparatus for embryonic stem cell culture
US7787197B2 (en) * 2007-09-14 2010-08-31 Becton, Dickinson And Company Beam-adjusting optics
EP2789689B1 (en) 2009-06-29 2016-04-27 Luminex Corporation Chimeric primers with hairpin conformations and methods of using same
US8223445B2 (en) * 2009-09-21 2012-07-17 Cytopeia Lens positioning apparatus
US8589851B2 (en) * 2009-12-15 2013-11-19 Memoir Systems, Inc. Intelligent memory system compiler
US8952132B2 (en) 2011-02-07 2015-02-10 Research Development Foundation Engineered immunoglobulin FC polypeptides
CN103889448A (zh) 2011-04-29 2014-06-25 贝勒医学院 用于预防和治疗人、动物和细胞培养物感染的尿枝原体疫苗和抗体
CN104039978A (zh) 2011-09-29 2014-09-10 露美内克丝公司 水解探针
EP2809783A2 (en) 2012-02-02 2014-12-10 Invenra, Inc. High throughput screen for biologically active polypeptides
US20140378327A1 (en) 2013-06-19 2014-12-25 Luminex Corporation Real-time multiplexed hydrolysis probe assay using spectrally identifiable microspheres
EP3461913B1 (en) 2013-08-09 2020-06-24 Luminex Corporation Probes for improved melt discrimination and multiplexing in nucleic acid assays
KR102465287B1 (ko) 2014-08-11 2022-11-09 루미넥스 코포레이션 핵산 검정에서 개선된 용융 판별 및 멀티플렉싱을 위한 프로브
CA2964467A1 (en) 2014-10-14 2016-04-21 Research Development Foundation Methods for generating engineered enzymes
US10457737B2 (en) 2015-02-09 2019-10-29 Research Development Foundation Engineered immunoglobulin Fc polypeptides displaying improved complement activation
WO2017040380A2 (en) 2015-08-28 2017-03-09 Research Development Foundation Engineered antibody fc variants
CN106383081B (zh) * 2016-08-22 2019-05-31 清华大学 基于二元光学器件的微流体芯片自动对准方法和系统
CN111936905B (zh) 2018-03-30 2023-01-06 Idexx实验室公司 流式细胞仪的激光光学组件
US11376320B2 (en) 2020-03-05 2022-07-05 Iowa State University Research Foundation, Inc. Immunogenic and vaccine compositions against SARS-CoV-2
EP4536276A1 (en) 2022-06-10 2025-04-16 Research Development Foundation Engineered fcriib selective igg1 fc variants and uses thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5039595A (en, 2012) * 1973-07-05 1975-04-11
JPS5979834A (ja) * 1982-10-29 1984-05-09 Japan Spectroscopic Co 微小粒子分離装置
JPS5979835A (ja) * 1982-10-29 1984-05-09 Japan Spectroscopic Co 微小粒子分析装置

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US3705771A (en) * 1970-01-14 1972-12-12 Bio Physics Systems Inc Photoanalysis apparatus
JPS5213423B2 (en, 2012) * 1971-10-15 1977-04-14
US3826364A (en) * 1972-05-22 1974-07-30 Univ Leland Stanford Junior Particle sorting method and apparatus
US3941477A (en) * 1974-10-17 1976-03-02 Deutsche Forschungs-Und Versuchsanstalt Fur Luft-Und Raumfahrt E.V. Measuring device for the measurement of fluid flow rates
DE2732272C2 (de) * 1977-07-16 1979-07-05 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts, 6900 Heidelberg Verfahren und Vorrichtung zur Fluoreszenzanalyse von gefärbten Partikeln, insbesondere biologischen Zellen
US4577964A (en) * 1978-09-06 1986-03-25 Ortho Diagnostics, Inc. Apparatus and method for detecting platelets in whole blood
US4293221A (en) * 1979-04-17 1981-10-06 Research Corporation Multidimensional slit-scan flow system
US4350892A (en) * 1980-07-31 1982-09-21 Research Corporation X'-, Y'-, Z'- axis multidimensional slit-scan flow system
US4498766A (en) * 1982-03-25 1985-02-12 Becton, Dickinson And Company Light beam focal spot elongation in flow cytometry devices
JPS59184841A (ja) * 1983-04-05 1984-10-20 ベクトン・デイツキンソン・アンド・カンパニ− サンプル中の白血球のサブクラスを識別する方法および装置
DD232552A1 (de) * 1983-08-04 1986-01-29 Adw Ddr Verfahren und einrichtung zur zaehlung und klassifizierung von dispergierten teilchen
US4660971A (en) * 1984-05-03 1987-04-28 Becton, Dickinson And Company Optical features of flow cytometry apparatus

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5039595A (en, 2012) * 1973-07-05 1975-04-11
JPS5979834A (ja) * 1982-10-29 1984-05-09 Japan Spectroscopic Co 微小粒子分離装置
JPS5979835A (ja) * 1982-10-29 1984-05-09 Japan Spectroscopic Co 微小粒子分析装置

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09508703A (ja) * 1994-08-01 1997-09-02 アボツト・ラボラトリーズ フローサイトメトリック血液細胞分析器用の擬似テレセントリック光学設計
JP2004109010A (ja) * 2002-09-19 2004-04-08 Otsuka Denshi Co Ltd 散乱光測定装置

Also Published As

Publication number Publication date
EP0210343A1 (en) 1987-02-04
JPH0544622B2 (en, 2012) 1993-07-06
EP0210343B1 (en) 1991-02-20
US4989977A (en) 1991-02-05
MY102913A (en) 1993-03-31
DE3677554D1 (de) 1991-03-28

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