JPS62118878A - 細胞培養装置 - Google Patents
細胞培養装置Info
- Publication number
- JPS62118878A JPS62118878A JP60258269A JP25826985A JPS62118878A JP S62118878 A JPS62118878 A JP S62118878A JP 60258269 A JP60258269 A JP 60258269A JP 25826985 A JP25826985 A JP 25826985A JP S62118878 A JPS62118878 A JP S62118878A
- Authority
- JP
- Japan
- Prior art keywords
- culture
- medium
- cells
- dishes
- metal filter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000004113 cell culture Methods 0.000 title claims description 5
- 239000002184 metal Substances 0.000 claims abstract description 21
- 239000002609 medium Substances 0.000 abstract description 36
- 239000001963 growth medium Substances 0.000 abstract description 19
- 239000000853 adhesive Substances 0.000 abstract description 4
- 230000001070 adhesive effect Effects 0.000 abstract description 4
- 235000015097 nutrients Nutrition 0.000 abstract description 4
- 238000002156 mixing Methods 0.000 abstract description 3
- 230000035755 proliferation Effects 0.000 abstract description 3
- 239000002699 waste material Substances 0.000 abstract description 3
- 238000011084 recovery Methods 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 28
- 238000000034 method Methods 0.000 description 18
- 239000012510 hollow fiber Substances 0.000 description 10
- 239000007789 gas Substances 0.000 description 7
- 239000011521 glass Substances 0.000 description 7
- 238000012258 culturing Methods 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 230000001464 adherent effect Effects 0.000 description 4
- 210000004102 animal cell Anatomy 0.000 description 4
- 239000000969 carrier Substances 0.000 description 4
- 239000000919 ceramic Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 239000011324 bead Substances 0.000 description 3
- 239000012634 fragment Substances 0.000 description 3
- 230000012010 growth Effects 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 235000010582 Pisum sativum Nutrition 0.000 description 2
- 240000004713 Pisum sativum Species 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000003513 alkali Substances 0.000 description 2
- 230000010261 cell growth Effects 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000012737 fresh medium Substances 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 239000012533 medium component Substances 0.000 description 2
- 239000002985 plastic film Substances 0.000 description 2
- 229920006255 plastic film Polymers 0.000 description 2
- 238000010008 shearing Methods 0.000 description 2
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 241000219745 Lupinus Species 0.000 description 1
- 241001274216 Naso Species 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 230000004956 cell adhesive effect Effects 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 230000005757 colony formation Effects 0.000 description 1
- 230000001332 colony forming effect Effects 0.000 description 1
- 238000012136 culture method Methods 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 210000004013 groin Anatomy 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 229940079322 interferon Drugs 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 239000011325 microbead Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60258269A JPS62118878A (ja) | 1985-11-18 | 1985-11-18 | 細胞培養装置 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60258269A JPS62118878A (ja) | 1985-11-18 | 1985-11-18 | 細胞培養装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62118878A true JPS62118878A (ja) | 1987-05-30 |
| JPH0585156B2 JPH0585156B2 (enrdf_load_html_response) | 1993-12-06 |
Family
ID=17317890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60258269A Granted JPS62118878A (ja) | 1985-11-18 | 1985-11-18 | 細胞培養装置 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS62118878A (enrdf_load_html_response) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5443985A (en) * | 1993-07-22 | 1995-08-22 | Alberta Research Council | Cell culture bioreactor |
| JP2007267619A (ja) * | 2006-03-30 | 2007-10-18 | Japan Tissue Engineering:Kk | 培養組織用トレイおよびこれの操作ユニット |
| JPWO2005059091A1 (ja) * | 2003-12-18 | 2007-12-13 | 株式会社日立メディコ | 細胞培養装置 |
-
1985
- 1985-11-18 JP JP60258269A patent/JPS62118878A/ja active Granted
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5443985A (en) * | 1993-07-22 | 1995-08-22 | Alberta Research Council | Cell culture bioreactor |
| JPWO2005059091A1 (ja) * | 2003-12-18 | 2007-12-13 | 株式会社日立メディコ | 細胞培養装置 |
| US7754478B2 (en) | 2003-12-18 | 2010-07-13 | Kaneka Corporation | Device for cell culture |
| JP2010268813A (ja) * | 2003-12-18 | 2010-12-02 | Kaneka Corp | 細胞培養装置 |
| JP2007267619A (ja) * | 2006-03-30 | 2007-10-18 | Japan Tissue Engineering:Kk | 培養組織用トレイおよびこれの操作ユニット |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0585156B2 (enrdf_load_html_response) | 1993-12-06 |
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