JPS62114954A - Ｎ−ベンゾイル−ｄｌ−メチオニンの光学分割方法 - Google Patents
Ｎ−ベンゾイル−ｄｌ−メチオニンの光学分割方法Info
- Publication number
- JPS62114954A JPS62114954A JP25491885A JP25491885A JPS62114954A JP S62114954 A JPS62114954 A JP S62114954A JP 25491885 A JP25491885 A JP 25491885A JP 25491885 A JP25491885 A JP 25491885A JP S62114954 A JPS62114954 A JP S62114954A
- Authority
- JP
- Japan
- Prior art keywords
- methionine
- benzoyl
- optical
- optical resolution
- met
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003287 optical effect Effects 0.000 title claims abstract description 19
- 238000000034 method Methods 0.000 title claims abstract description 16
- PPFRJEXUPZWQPI-UHFFFAOYSA-N 2-benzamido-4-methylsulfanylbutanoic acid Chemical compound CSCCC(C(O)=O)NC(=O)C1=CC=CC=C1 PPFRJEXUPZWQPI-UHFFFAOYSA-N 0.000 title claims abstract description 11
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 14
- BOWUOGIPSRVRSJ-UHFFFAOYSA-N 2-aminohexano-6-lactam Chemical compound NC1CCCCNC1=O BOWUOGIPSRVRSJ-UHFFFAOYSA-N 0.000 claims abstract description 4
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract description 6
- PPFRJEXUPZWQPI-JTQLQIEISA-N (2s)-2-benzamido-4-methylsulfanylbutanoic acid Chemical compound CSCC[C@@H](C(O)=O)NC(=O)C1=CC=CC=C1 PPFRJEXUPZWQPI-JTQLQIEISA-N 0.000 abstract description 4
- 229960004452 methionine Drugs 0.000 abstract description 4
- UQDJGEHQDNVPGU-UHFFFAOYSA-N serine phosphoethanolamine Chemical compound [NH3+]CCOP([O-])(=O)OCC([NH3+])C([O-])=O UQDJGEHQDNVPGU-UHFFFAOYSA-N 0.000 abstract description 4
- FFEARJCKVFRZRR-UHFFFAOYSA-N L-Methionine Natural products CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 abstract description 3
- 229930195722 L-methionine Natural products 0.000 abstract description 3
- 230000002255 enzymatic effect Effects 0.000 abstract description 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract description 2
- 239000002994 raw material Substances 0.000 abstract description 2
- 239000013543 active substance Substances 0.000 abstract 4
- 230000002194 synthesizing effect Effects 0.000 abstract 2
- 238000007796 conventional method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 description 16
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
- 239000002904 solvent Substances 0.000 description 7
- 239000013078 crystal Substances 0.000 description 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000005199 ultracentrifugation Methods 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25491885A JPS62114954A (ja) | 1985-11-15 | 1985-11-15 | Ｎ−ベンゾイル−ｄｌ−メチオニンの光学分割方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25491885A JPS62114954A (ja) | 1985-11-15 | 1985-11-15 | Ｎ−ベンゾイル−ｄｌ−メチオニンの光学分割方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62114954A true JPS62114954A (ja) | 1987-05-26 |
| JPH0255419B2 JPH0255419B2 (enrdf_load_stackoverflow) | 1990-11-27 |
Family
ID=17271664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP25491885A Granted JPS62114954A (ja) | 1985-11-15 | 1985-11-15 | Ｎ−ベンゾイル−ｄｌ−メチオニンの光学分割方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS62114954A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008297281A (ja) * | 2007-06-01 | 2008-12-11 | Daito Kagaku Kk | 光学活性ｎ−ベンジルオキシカルボニルアミノ酸の製造方法およびジアステレオマー塩 |
-
1985
- 1985-11-15 JP JP25491885A patent/JPS62114954A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008297281A (ja) * | 2007-06-01 | 2008-12-11 | Daito Kagaku Kk | 光学活性ｎ−ベンジルオキシカルボニルアミノ酸の製造方法およびジアステレオマー塩 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0255419B2 (enrdf_load_stackoverflow) | 1990-11-27 |
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