JPS6149314B2 - - Google Patents

Info

Publication number
JPS6149314B2
JPS6149314B2 JP52158546A JP15854677A JPS6149314B2 JP S6149314 B2 JPS6149314 B2 JP S6149314B2 JP 52158546 A JP52158546 A JP 52158546A JP 15854677 A JP15854677 A JP 15854677A JP S6149314 B2 JPS6149314 B2 JP S6149314B2
Authority
JP
Japan
Prior art keywords
piperazine
thiadiazol
general formula
formula
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP52158546A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5384984A (en
Inventor
Regunieeru Giruberuto
Kanebari Roje
Raubie Misheru
Kuroodo Hoigunanto Jan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHIANSU YUNION E CO SOC FURANSEEZU DO RUSHERUSHU MEDEIKARU
Original Assignee
SHIANSU YUNION E CO SOC FURANSEEZU DO RUSHERUSHU MEDEIKARU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHIANSU YUNION E CO SOC FURANSEEZU DO RUSHERUSHU MEDEIKARU filed Critical SHIANSU YUNION E CO SOC FURANSEEZU DO RUSHERUSHU MEDEIKARU
Publication of JPS5384984A publication Critical patent/JPS5384984A/ja
Publication of JPS6149314B2 publication Critical patent/JPS6149314B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
JP15854677A 1976-12-31 1977-12-27 Disubstituted piperazine process for preparing same and medical composition containing same Granted JPS5384984A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB54398/76A GB1560084A (en) 1976-12-31 1976-12-31 Disubstituted piperazines processes for their preparation and pharmaceutical mompositions containing them

Publications (2)

Publication Number Publication Date
JPS5384984A JPS5384984A (en) 1978-07-26
JPS6149314B2 true JPS6149314B2 (enExample) 1986-10-29

Family

ID=10470884

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15854677A Granted JPS5384984A (en) 1976-12-31 1977-12-27 Disubstituted piperazine process for preparing same and medical composition containing same

Country Status (24)

Country Link
US (1) US4177272A (enExample)
JP (1) JPS5384984A (enExample)
AR (3) AR216931A1 (enExample)
AT (1) AT358591B (enExample)
AU (1) AU513087B2 (enExample)
BE (1) BE862568A (enExample)
CA (1) CA1100968A (enExample)
DD (1) DD133802A5 (enExample)
DE (1) DE2758314A1 (enExample)
DK (1) DK572977A (enExample)
FR (1) FR2376148A1 (enExample)
GB (1) GB1560084A (enExample)
GR (1) GR62407B (enExample)
IE (1) IE46284B1 (enExample)
IL (1) IL53714A (enExample)
NL (1) NL7714628A (enExample)
NZ (1) NZ186158A (enExample)
OA (1) OA05840A (enExample)
PH (1) PH14321A (enExample)
PT (1) PT67486B (enExample)
SE (1) SE7714884L (enExample)
SU (2) SU703021A3 (enExample)
YU (1) YU304377A (enExample)
ZA (1) ZA777680B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2418798A1 (fr) * 1978-03-03 1979-09-28 Science Union & Cie Nouvelles piperazines disubstituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
US4421753A (en) * 1982-01-15 1983-12-20 American Cyanamid Company 1-(5-Amino-4H-1,2,4-triazol-3-yl)-4-substituted-piperazines
FR2519986A1 (fr) * 1982-01-21 1983-07-22 Adir Nouveaux derives de benzodioxine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
US5637592A (en) * 1994-07-12 1997-06-10 Janssen Pharmaceutica N.V. Acyl derivatives of azolones
FR2799464B1 (fr) * 1999-10-12 2001-12-28 Norchim Procede de fabrication de piperonyl piperazine par animation reductive
US10562869B2 (en) 2014-03-17 2020-02-18 Remynd Nv Oxadiazole compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1595923A1 (de) * 1965-02-20 1969-11-27 Merck Ag E 1-Aralkyl-4-(thiazolyl-2)-piperazine und Verfahren zu ihrer Herstellung
GB1307256A (en) * 1970-09-15 1973-02-14 Science Union & Cie Piperazine derivatives and a process for their preparation
GB1369379A (en) * 1972-04-07 1974-10-09 Science Union & Cie Benzodioxole derivatives and processes for preparing them
GB1407552A (en) * 1973-04-02 1975-09-24 Science Union & Cie Disubstituted piperazines processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
YU304377A (en) 1983-01-21
FR2376148A1 (fr) 1978-07-28
FR2376148B1 (enExample) 1981-05-29
ATA927577A (de) 1980-02-15
JPS5384984A (en) 1978-07-26
BE862568A (fr) 1978-06-30
ZA777680B (en) 1978-10-25
GR62407B (en) 1979-04-11
IE46284L (en) 1978-06-30
IL53714A0 (en) 1978-03-10
AU513087B2 (en) 1980-11-13
IL53714A (en) 1981-07-31
AU3204577A (en) 1979-07-05
CA1100968A (fr) 1981-05-12
AT358591B (de) 1980-09-25
NZ186158A (en) 1980-03-05
AR217144A1 (es) 1980-02-29
OA05840A (fr) 1981-05-31
PT67486B (fr) 1979-05-30
SU793397A3 (ru) 1980-12-30
DD133802A5 (de) 1979-01-24
DK572977A (da) 1978-07-01
AR217143A1 (es) 1980-02-29
PH14321A (en) 1981-05-27
NL7714628A (nl) 1978-07-04
GB1560084A (en) 1980-01-30
SU703021A3 (ru) 1979-12-05
US4177272A (en) 1979-12-04
IE46284B1 (en) 1983-04-20
PT67486A (fr) 1978-01-01
AR216931A1 (es) 1980-02-15
SE7714884L (sv) 1978-07-02
DE2758314A1 (de) 1978-07-06

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