JPS61189219A - 安定な活性型ビタミンｄ↓３類含有製剤 - Google Patents
安定な活性型ビタミンｄ↓３類含有製剤Info
- Publication number
- JPS61189219A JPS61189219A JP2793985A JP2793985A JPS61189219A JP S61189219 A JPS61189219 A JP S61189219A JP 2793985 A JP2793985 A JP 2793985A JP 2793985 A JP2793985 A JP 2793985A JP S61189219 A JPS61189219 A JP S61189219A
- Authority
- JP
- Japan
- Prior art keywords
- activated vitamin
- panacete
- light
- heat
- soft capsule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title abstract description 4
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical class C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 title description 5
- 239000007901 soft capsule Substances 0.000 claims abstract description 16
- 150000003704 vitamin D3 derivatives Chemical class 0.000 claims abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 abstract description 5
- 150000001875 compounds Chemical class 0.000 abstract description 4
- 229940079593 drug Drugs 0.000 abstract description 4
- 239000003814 drug Substances 0.000 abstract description 4
- 208000020084 Bone disease Diseases 0.000 abstract description 2
- 208000013038 Hypocalcemia Diseases 0.000 abstract description 2
- 230000000705 hypocalcaemia Effects 0.000 abstract description 2
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 3
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 6
- 238000000034 method Methods 0.000 description 4
- 150000003710 vitamin D derivatives Chemical class 0.000 description 4
- 229930003316 Vitamin D Natural products 0.000 description 3
- 239000002775 capsule Substances 0.000 description 3
- 235000019166 vitamin D Nutrition 0.000 description 3
- 239000011710 vitamin D Substances 0.000 description 3
- 235000005282 vitamin D3 Nutrition 0.000 description 3
- 239000011647 vitamin D3 Substances 0.000 description 3
- 229940046008 vitamin d Drugs 0.000 description 3
- 229940021056 vitamin d3 Drugs 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000001766 physiological effect Effects 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 239000012488 sample solution Substances 0.000 description 2
- 150000004671 saturated fatty acids Chemical class 0.000 description 2
- 235000010199 sorbic acid Nutrition 0.000 description 2
- 150000003398 sorbic acids Chemical class 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 2
- 229920000858 Cyclodextrin Polymers 0.000 description 1
- 108010034984 D3 compound Proteins 0.000 description 1
- 208000000038 Hypoparathyroidism Diseases 0.000 description 1
- 208000001132 Osteoporosis Diseases 0.000 description 1
- 241000590428 Panacea Species 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 239000006097 ultraviolet radiation absorber Substances 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2793985A JPS61189219A (ja) | 1985-02-15 | 1985-02-15 | 安定な活性型ビタミンｄ↓３類含有製剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2793985A JPS61189219A (ja) | 1985-02-15 | 1985-02-15 | 安定な活性型ビタミンｄ↓３類含有製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS61189219A true JPS61189219A (ja) | 1986-08-22 |
| JPH0533686B2 JPH0533686B2 (enrdf_load_stackoverflow) | 1993-05-20 |
Family
ID=12234865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2793985A Granted JPS61189219A (ja) | 1985-02-15 | 1985-02-15 | 安定な活性型ビタミンｄ↓３類含有製剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS61189219A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6421A (en) * | 1987-02-27 | 1989-01-05 | Teijin Ltd | Preventive for osteoporosis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5326316A (en) * | 1976-08-20 | 1978-03-11 | Teijin Ltd | Drug containing active vitamin d3 derivatives and its preparation |
-
1985
- 1985-02-15 JP JP2793985A patent/JPS61189219A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5326316A (en) * | 1976-08-20 | 1978-03-11 | Teijin Ltd | Drug containing active vitamin d3 derivatives and its preparation |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6421A (en) * | 1987-02-27 | 1989-01-05 | Teijin Ltd | Preventive for osteoporosis |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0533686B2 (enrdf_load_stackoverflow) | 1993-05-20 |
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