JPS61171407A - Emulsion type cosmetic - Google Patents

Abstract

PURPOSE:An emulsion type cosmetic acting mildly on the skin and the hair, having improved emulsification and emulsion stability, good touch, moisture retention, appearance, etc., comprising an emulsifying agent consisting of mono- O-acryl-3-glycerilphosphorylchloline, an oily substance, and water. CONSTITUTION:A cosmetic comprising 0.01-10wt% emulsifying agent, 10-80wt% oily substance, and water. A mono-O-acryl-3-glyceryl- phosphorylchloline such as 1-palmitoyl-3-glycerylphosphorylcholine shown by the formula I, 1-stearoyl-phosphorylcholine shown by the formula II, etc., is used as the emulsifying agent, and liquid paraffin, olive oil, beef tallow, bees wax, lauric acid, etc., is used as the oily substance. The cosmetic has improved properties for use such as removal, spread, and improved appearance such as luster, fineness, etc.

Description

DETAILED DESCRIPTION OF THE INVENTION (Industrial Field of Application) The present invention relates to an emulsified cosmetic prepared by emulsifying an oily substance using a specific mono-O-acyl-3-glycerylphosphorylcholine described below as an emulsifier. For more details,
Mildly acts on skin and hair, has excellent emulsifying properties, storage stability (stability over time), and has good feel, moisturizing properties, usability (removal, extension, etc.), and appearance (gloss, texture, etc.) The present invention relates to emulsified cosmetics.

(Prior Art) Conventionally, the requirements for emulsified cosmetics such as creams and emulsions are: (1) High safety without irritating the skin or hair.

(2) Good emulsion stability even during long-term storage.

(3) Good appearance such as texture and gloss.

(4) Good release, spreadability, feel (gives a light and moist feeling to the skin, does not give a sticky feeling), etc. when used.

(5) Skin 1: To provide adequate moisture retention (water retention) to hair.

(6) No deterioration or odor will occur even after long-term storage.

etc.

However, in order to satisfy these conditions, careful formulation design such as the selection and specific combination of emulsifiers and the combined use of special bases has been carried out, but it is not easy to achieve these objectives.

Emulsified cosmetics that use ordinary synthetic emulsifiers (such as anionic or nonionic synthetic surfactants) as emulsifiers (
For example, creams, etc.) generally have the disadvantage that they tend to irritate the skin and hair.

On the other hand, lecithins such as egg yolk lecithin and soybean lecithin are known as natural emulsifiers that are mild to the skin, but their emulsifying power is not sufficient due to their oily substances. Further O
/ When making a W-type emulsion, there were disadvantages such as phase inversion to W10W emulsion near room temperature, poor appearance and emulsification properties (not so good), and deterioration and odor during long-term storage. .

(Problems to be Solved by the Invention) As a result of intensive research to develop a phospholipid-based emulsifier that improves the drawbacks of the prior art, the present inventors found that the specific mono-O-acyl-3-glycerylphosphorylcholine described below can emulsify oil-based substances uniformly, has a mild effect on skin and hair, has excellent emulsifying properties and storage stability, and has a pleasant texture.
Moisture retention, usability (removal, elongation, etc.), and appearance (gloss,
The present invention was completed based on the discovery that it is possible to easily produce emulsified cosmetics with good texture (texture, etc.).

The purpose of the present invention is to provide a product that does not irritate the skin or hair, has a mild effect, and has emulsifying properties.

An object of the present invention is to provide an emulsified cosmetic that has excellent storage stability and also has good feel, moisturizing properties, usability (removal, spreading, etc.), and appearance (gloss, texture, etc.).

Another object of the present invention is to provide a novel emulsifier useful for producing emulsified cosmetics. Still another object is to create an emulsified cosmetic whose prescription design (composition design) is acceptable without the use of synthetic surfactants, and which can be industrially advantageously produced. The main constituent components are an emulsifier, an oily substance, and water, and 1 as an emulsifier.
- Pal Mawari Toil 3- Glycerylphosphorylcholine, 2
-Palmitoyl-3-glycerylphosphorylcholine, 1
-stearoyl-3-glycerylphosphorylcholine, 2
This is achieved by an emulsified cosmetic containing at least one mono-O-acyl-3-glycerylphosphorylcholine selected from the group consisting of -stearoyl-8-glycerylphosphorylcholine.

The specific mono-O-acyl-3-glycerylphosphorylcholine in the present invention is a known compound and is represented by the following structural formulas (1) to (4).

(111-Palmitoyl-3-glycerylphosphorylcholine〇- (2) 2-Palmitoyl-8-glycerylphosphorylcholine (3) 1-stearoyl-8-glycerylphosphorylcholine 14) 2-stearoyl-8-glycerylphosphorylcholine The above-mentioned specific mono〇- Acyl-a-glycerylphosphorylcholine can be obtained, for example, by treating phosphatidylcholine as a raw material with snake venom phospholipase or vancreatin, an enzyme extracted from pig pancreas, and fractionating it by high performance liquid chromatography. Furthermore, it can also be obtained by chemical synthesis.

The specific mono-0-acyl-3-glycerylphosphorylcholine is safe for the human body, and its skin irritation was evaluated according to the Draize method described later, and the animal skin irritation score and human skin irritation score were both 0.
(zero) and has been confirmed to be non-irritating.

[Draize, J.H., As5ociation
of Food and Drugs
ials of the United 5ta
tes.

” Appraisal of the 5af
ety of Chemicals 1nFood
s, Drugs and Cosmetics”,
46 (1959).

Texas, 5taLe Department
of Health*Au5tin,] The specific mono-O-acyl-3-glycerylphosphorylcholine in the present invention is used singly or in combination as an emulsifier. The usage amount (compounding amount) is 0 based on the total weight of the prescription ingredients in the cosmetic (composition weight).
．． 01 to 10% by weight, preferably 1 to 5% by weight.

If it is less than 0.01% by weight, the emulsification of the oily substance tends to be poor, and if it is more than 10% by weight, the solubility in the system decreases and the texture is not satisfactory.

These include animal fats and oils, vegetable fats and oils, waxes, higher alcohols, higher fatty acids, ester oils, silicone oils, and the like. Examples of hydrocarbons include liquid paraffin, squalane, microcrystalline wax, petrolatum, ceresin, and examples of vegetable oils include olive oil, castor oil,
Examples of animal fats and oils such as cacao butter and palm oil include:
Cod liver oil.

Waxes such as beef tallow and butter fat include beeswax,
Examples of higher fatty acids such as carnauba wax include lauric acid, myristic acid, valmitic acid, stearic acid,
Examples of higher alcohols include oleic acid, behenic acid, and lanolin fatty acids, as well as lauryl alcohol and stearyl alcohol.

Examples of ester oils such as cetyl alcohol and oleyl alcohol include straight chain esters and branched chain esters such as butyl stearate, hexyl laurate, octyl dodecyl lystate, diisopropyl adipate, diisopropyl sebacate, and the like.

These oily substances may be used alone or in combination of two or more. The amount used (blended amount) is 10 to 80% by weight, preferably 20 to 60% by weight, based on the total weight of the prescription ingredients in the cosmetic. If it is less than 10% by weight, the storage stability will be a little worse and the finish will be a little light to the touch, and if it is more than 80% by weight, the oil will become extremely sticky, which is not preferable.

The amount of water in the present invention ranges from 10 to 89.9% by weight, preferably from 20 to 80% by weight based on the total weight of the prescription components.
It is the amount of it%.

Mono〇-acyl-3-glycerylphosphorylcholine that can be used in the present invention! i Exhibits good surfactant ability (ability to lower interfacial tension) and can stably emulsify the oily substance, but
casein soda, pectin.

xanthan gum, karaya gum, locust bean gum,
When at least one water-soluble natural polymer selected from the group consisting of carrageenan is blended, the oily substance can be emulsified even more stably. The above-mentioned natural polymer may be used alone or in combination, preferably in an amount of 0.5 to 2% by weight.

In the cosmetics of the present invention, pine surge cream.

Cleansing creams, skin creams, skin milk, hair creams, etc. do not require the addition of pigments, but foundation silane creams and liquid makeup bases require the addition of pigments in addition to the above ingredients. The amount used is 10% by weight or less, preferably 0.5 to 7% by weight, based on the total weight of the prescription components.

Examples of pigments include titanium oxide and kaolin.

Inorganic pigments such as talc, mica, iron oxide and the like can be mentioned.

Additionally, a small amount of beauty medicinal ingredients and fragrances as desired.

It is also possible to add one preservative, one coloring agent, and one synthetic surfactant.

Examples of cream or milky cosmetics of the present invention include pine surge cream, cleansing cream, skin cream, skin milk, foundation cream,
liquid makeup base.

It is applied to many creamy or emulsion-like cosmetics such as hair creams for skin and hair.

The cream or milky lotion cosmetic of the present invention has a mild effect without irritating the skin and hair, and has a pleasant feel.
It has good moisturizing properties and usability (removal, spreadability, etc.), has a fine texture, has a good appearance with high gloss, and has excellent emulsifying properties and storage stability.

Examples will be described below.

! iI Parts shown in Examples mean parts by weight. Characteristics of emulsified cosmetics shown in Examples: Appearance (texture, gloss).

The usability (curl, elongation, etc.), tactile effect, etc. were examined by eight specialized inspectors. The texture is determined by the naked eye, and the gloss level is J
It was measured according to Method 2 of IS-Z-8741-1962 (7) Glossiness measurement method. The tactile effect is the feeling when applied to the skin,
The finish etc. after application were examined for the sample compositions. Usability (tearing, elongation, etc.) was determined by actually checking it with a finger.

Example 1 (skin cream) (1) Prescription ■ 1-Valmitoy-8-glycerylphosphorylcholine 8 parts ■ Liquid paraffin 50 parts ■ Cetyl alcohol
5 parts ■ Methyl paraoxybenzoate
0.2 parts ■Fragrance 0.2
Part ■ Purified water 41.6 parts (2)
Production method: Dissolve the oily components (1) and (2) of the above ingredients uniformly at about 80°C (solution 1). The water-soluble components (1), (2) and (2) of the above ingredients are uniformly dissolved at about 80°C (solution 2). Next, while stirring Solution 2 with a homomixer, Solution 1 is added and emulsified, followed by cooling. Incidentally, component (2) was added at 70° C. after cooling, and after the temperature was lowered to 80° C., stirring was stopped.

The skin cream thus obtained is an O/W type emulsion, with good appearance such as texture and gloss (gloss level = 90%), and good feel, moisturizing properties, and usability (removal, spreadability, etc.) at 40°C.
It remained extremely stable even after storage for 4 months in a constant temperature bath.

Moreover, 6-month dandan was also extremely stable at 5°C and 80°C. Furthermore, no deterioration or odor occurred.

Comparative Example 1 Instead of 1-palmitoyl-3-glycerylphosphorylcholine, phosphatidylcholine (1-balmitoyl-2
A comparative skin cream was prepared in the same manner as in Example 1, except that oleoyl-8-glycerylphosphorylcholine) was used.

As a result, the obtained skin cream was a Q/W type emulsion, had a very rough texture, and was glossy (gloss level = 50%).
It was bad, and the cream was even worse. When stored in a constant temperature bath at 40°C for 4 months, the emulsion separated into two layers, the emulsion stability was poor, and the quality changed (coloration).

Comparative Example 2 A comparative skin cream was prepared in the same manner as in Example 1, except that soybean lecithin was used instead of 1-palmitoyl-3-glycerylphosphorylcholine. As a result, the skin cream obtained was Wlo m emulsion 1
The texture of the skin was very rough and it was very rough. When stored for 4 months in a constant temperature bath at 40°C, it partially separated into two layers.

Furthermore, the color changed to brown and a bad odor occurred.

Example 2 (Skin Cream) A skin cream was prepared according to Example 1 using the formulation based on Table 1. The characteristics of each cream obtained are shown in Table 2.

Table 2 From Table 2, good reams were obtained when 1-stearoyl-8-glycerylphosphorylcholine was contained in an amount of 0.01 to 10%. On the other hand, if it is less than 0.01% by weight, it will not emulsify, and if it exceeds 10% by weight, it will be glossy.

It felt bad and became difficult to use. As is clear from the results, good skin creams were obtained when the amount of mono-0-acyl-3-glycerylphosphoryl-phosphorus was 0.01 to 10% by weight (preferably 1 to 5% by weight).

Example B (Cleansing Cream) A product was produced in the same manner as in Example 1, except that the weight part of the liquid paraffin used in Example 1 was varied. Table 8 shows the characteristics of each cream obtained. As is clear from this result,
The blending amount of the oily substance is 10 to 80% by weight (preferably,
Table 8 Example 4 (Skin milk) (1) Prescription ■ Cetyl alcohol 5.0 parts ■ Octyldodecyl myristate 1. 5■Liquid paraffin 20. O xanthan gum
2.0■2-palmitoyl-3-glycerylphosphorylcholine 8.0■Methyl paraoxybenzoate 0.2■Fragrance
0.2 ■ Purified water
68.1+21 Illll The oily components (1) to (2) of the above method components are uniformly dissolved at about 80°C (solution 1). The water-soluble components (1) to (2) and (2) of the above components are uniformly dissolved at about 80°C (solution 2). Next, Solution 1 is added to Solution 2 while stirring with a homomixer, emulsified, and then cooled. During the cooling process, component (2) was added at 70'C, and after the temperature was lowered to 30'C, stirring was stopped.

The skin milk thus obtained is an O/W type emulsion with good appearance such as texture and gloss (gloss level = 86%).
The feel (fits into the skin, finish), moisturizing properties, and usability (spreading) are also good.It was extremely stable even after being stored in a hot water bath at <40'C for 2 months. The 4-month food was also extremely stable at 5°C and 30°C. Furthermore, no deterioration or odor occurred.

Example 5 (hair cream) +ll Prescription ■ Cetyl alcohol 1° 5 parts ■ Microcrystalline wax 5.0 ■ Beeswax
2.5 ■ Glyceryl monostearate 1. .

■Liquid paraffin 40.0■2-stearoyl-8-glycerylphosphorylcholine 8.0■Methyl paraoxybenzoate 0.2■Fragrance
0.2 ■ Purified water
46.6 (2) Manufacturing method The oily components (1) to (4) of the above ingredients are uniformly dissolved at about 80°C (solution 1). Uniformly dissolve the water-soluble components (1), (2), and (2) of the above ingredients at approximately 80°C (Solution 2) 6. Next, add Solution 1 while stirring Solution 2 with a homomixer, emulsify, and then cool. . During the cooling process, component (2) was added at 70°C, and after the temperature was lowered to 80°C, stirring was stopped.

The hair cream obtained in this way is an O/W type emulsion, and has excellent appearance such as texture and gloss (gloss level = 98%), is easy to apply to the hair and scalp, has good blending, and also makes the hair extremely soft. I made it. It remained stable even after storage for 2 months in a constant temperature bath at 40°C. Furthermore, the 5-month machine was stable at 5'C and 80'C, and no deterioration or odor occurred.

Example 6 (Foundage 1 Cream) (1) Prescription ■Liquid paraffin 45.0 parts■Ceresin 5.0■Glyceryl monostearate 1.0■1-palmitoyl-3
-Glycerylphosphorylcholine 8.5■Methyl paraoxybenzoate 0.2■Titanium oxide
2.5 ■Kaolin
1.2■・Talc
1.8 ■ Yellow iron oxide
0.3 @ Purified water 40.
0(2) According to the manufacturing method Example 5.

The foundation 1 cream thus obtained is a 07W type emulsion with good appearance, feel, moisturizing properties, and ease of use.
It was stable for 2 months in a constant temperature bath at 40°C, and extremely stable even after 6 months at 5°C and 80°C. Furthermore, no deterioration or odor occurred.

Procedural amendment (spontaneous) September 1985 Director General of the Japan Patent Office Michibe Uga 1, □0□ Recent Patent Application No. 11607 2, Name of invention Emulsified Cosmetic 8, Person making the amendment Relationship to the case Patent applicant address 5-17-4 Sumida, Sumida-ku, Tokyo 534
Kanebo Co., Ltd. Patent Department, 1-5-90 Tomobuchi-cho, Bejima-ku, Osaka City Phone: (06) 921-1251 4. Number of inventions increased by amendment None 6. Contents of amendment (1) Specification, page 7 Correct "0-" written at the bottom of the second line to "0-".

Claims (3)

[Claims] (1) The main constituent components are an emulsifier, an oily substance, and water, and the emulsifiers are 1-palmitoyl-3-glycerylphosphorylcholine, 2-palmitoyl-3-glycerylphosphorylcholine, 1-stearoyl-3-glycerylphosphorylcholine, and 2-stearoyl -Mono-O selected from the group consisting of -3-glycerylphosphorylcholine
- An emulsified cosmetic containing at least one of acyl-3-glycerylphosphorylcholine. (2) Claim 1, wherein at least one of the mono-O-acyl-3-glycerylphosphorylcholine is blended in an amount of 0.01 to 10% by weight based on the total weight of the prescription ingredients. Emulsified cosmetics. (3) The emulsified cosmetic according to claim (1), wherein the oily substance is blended in an amount of 10 to 80% by weight based on the total weight of the prescription ingredients.