JPS61152694A - 新規な５−フルオロ−２′−デオキシウリジン−５′−ホスフエ−ト誘導体およびその塩 - Google Patents

新規な５−フルオロ−２′−デオキシウリジン−５′−ホスフエ−ト誘導体およびその塩

Info

Publication number
JPS61152694A
JPS61152694A JP59273919A JP27391984A JPS61152694A JP S61152694 A JPS61152694 A JP S61152694A JP 59273919 A JP59273919 A JP 59273919A JP 27391984 A JP27391984 A JP 27391984A JP S61152694 A JPS61152694 A JP S61152694A
Authority
JP
Japan
Prior art keywords
salt
formula
fluoro
compound
phosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59273919A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0517920B2 (enrdf_load_stackoverflow
Inventor
Takako Hori
堀　孝子
Isao Myokan
勇雄 明官
Maki Miyahara
宮原　真樹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Priority to JP59273919A priority Critical patent/JPS61152694A/ja
Publication of JPS61152694A publication Critical patent/JPS61152694A/ja
Publication of JPH0517920B2 publication Critical patent/JPH0517920B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
JP59273919A 1984-12-27 1984-12-27 新規な５−フルオロ−２′−デオキシウリジン−５′−ホスフエ−ト誘導体およびその塩 Granted JPS61152694A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP59273919A JPS61152694A (ja) 1984-12-27 1984-12-27 新規な５−フルオロ−２′−デオキシウリジン−５′−ホスフエ−ト誘導体およびその塩

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59273919A JPS61152694A (ja) 1984-12-27 1984-12-27 新規な５−フルオロ−２′−デオキシウリジン−５′−ホスフエ−ト誘導体およびその塩

Publications (2)

Publication Number Publication Date
JPS61152694A true JPS61152694A (ja) 1986-07-11
JPH0517920B2 JPH0517920B2 (enrdf_load_stackoverflow) 1993-03-10

Family

ID=17534395

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59273919A Granted JPS61152694A (ja) 1984-12-27 1984-12-27 新規な５−フルオロ−２′−デオキシウリジン−５′−ホスフエ−ト誘導体およびその塩

Country Status (1)

Country Link
JP (1) JPS61152694A (enrdf_load_stackoverflow)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5032680A (en) * 1988-02-29 1991-07-16 Kuraray Co., Ltd. 2'-deoxy-5-fluorouridine derivatives
US5051499A (en) * 1986-09-27 1991-09-24 Toyo Jozo Kabushiki Kaisha Novel nucleoside-phospholipid conjugate
JP2003514770A (ja) * 1999-09-14 2003-04-22 ディ − ファーム リミテッド 抗増殖性医薬の燐脂質プロドラッグ
WO2003044035A1 (de) * 2001-11-21 2003-05-30 Ganymed 256 Vermögensverwaltungs Gmbh Phospholipid-derivate von nucleosiden als antitumorale arzneimittel
US7517858B1 (en) * 1995-06-07 2009-04-14 The Regents Of The University Of California Prodrugs of pharmaceuticals with improved bioavailability
US7749983B2 (en) 2006-05-03 2010-07-06 Chimerix, Inc. Metabolically stable alkoxyalkyl esters of antiviral or antiproliferative phosphonates, nucleoside phosphonates and nucleoside phosphates
US8993542B2 (en) 2008-01-25 2015-03-31 Chimerix Inc. Methods of treating viral infections
US9006218B2 (en) 2010-02-12 2015-04-14 Chimerix Inc. Nucleoside phosphonate salts
US9278135B2 (en) 2010-04-26 2016-03-08 Chimerix Inc. Methods of treating retroviral infections and related dosage regimes

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051499A (en) * 1986-09-27 1991-09-24 Toyo Jozo Kabushiki Kaisha Novel nucleoside-phospholipid conjugate
US5032680A (en) * 1988-02-29 1991-07-16 Kuraray Co., Ltd. 2'-deoxy-5-fluorouridine derivatives
US7517858B1 (en) * 1995-06-07 2009-04-14 The Regents Of The University Of California Prodrugs of pharmaceuticals with improved bioavailability
JP2003514770A (ja) * 1999-09-14 2003-04-22 ディ − ファーム リミテッド 抗増殖性医薬の燐脂質プロドラッグ
WO2003044035A1 (de) * 2001-11-21 2003-05-30 Ganymed 256 Vermögensverwaltungs Gmbh Phospholipid-derivate von nucleosiden als antitumorale arzneimittel
US7994143B2 (en) 2006-05-03 2011-08-09 Chimerix, Inc. Metabolically stable alkoxyalkyl esters of antiviral or antiproliferative phosphonates, nucleoside phosphonates and nucleoside phosphates
US7749983B2 (en) 2006-05-03 2010-07-06 Chimerix, Inc. Metabolically stable alkoxyalkyl esters of antiviral or antiproliferative phosphonates, nucleoside phosphonates and nucleoside phosphates
EP2012799A4 (en) * 2006-05-03 2013-03-20 Chimerix Inc METABOLIC STABILIZED ALKOXYALKYL ESTERS OF ANTIVIRAL OR ANTIPROLIFERATIVE PHOSPHONATES, NUCLEOSIDE PHOSPHONATES AND NUCLEOSIDE PHOSPHATES
US8993542B2 (en) 2008-01-25 2015-03-31 Chimerix Inc. Methods of treating viral infections
US9006218B2 (en) 2010-02-12 2015-04-14 Chimerix Inc. Nucleoside phosphonate salts
US9765100B2 (en) 2010-02-12 2017-09-19 Chimerix, Inc. Nucleoside phosphonate salts
US9278135B2 (en) 2010-04-26 2016-03-08 Chimerix Inc. Methods of treating retroviral infections and related dosage regimes
US9694024B2 (en) 2010-04-26 2017-07-04 Chimerix, Inc. Methods of treating retroviral infections and related dosage regimes
US9956239B2 (en) 2010-04-26 2018-05-01 Chimerix, Inc. Methods of treating retroviral infections and related dosage regimes

Also Published As

Publication number Publication date
JPH0517920B2 (enrdf_load_stackoverflow) 1993-03-10

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