JPS603830B2 - インビトロでの植物細胞の培養法 - Google Patents
インビトロでの植物細胞の培養法Info
- Publication number
- JPS603830B2 JPS603830B2 JP56169391A JP16939181A JPS603830B2 JP S603830 B2 JPS603830 B2 JP S603830B2 JP 56169391 A JP56169391 A JP 56169391A JP 16939181 A JP16939181 A JP 16939181A JP S603830 B2 JPS603830 B2 JP S603830B2
- Authority
- JP
- Japan
- Prior art keywords
- medium
- plant cells
- culture
- cells
- strain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title claims abstract description 43
- 238000000338 in vitro Methods 0.000 title claims abstract description 6
- 238000012258 culturing Methods 0.000 title claims description 15
- 239000007788 liquid Substances 0.000 claims abstract description 27
- 239000002207 metabolite Substances 0.000 claims abstract description 10
- 241000196324 Embryophyta Species 0.000 claims description 29
- 206010020649 Hyperkeratosis Diseases 0.000 claims description 9
- 239000006285 cell suspension Substances 0.000 claims description 3
- 241000218922 Magnoliophyta Species 0.000 claims description 2
- 238000003756 stirring Methods 0.000 claims description 2
- 230000004584 weight gain Effects 0.000 claims 1
- 235000019786 weight gain Nutrition 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract description 13
- 230000008569 process Effects 0.000 abstract description 4
- 230000036983 biotransformation Effects 0.000 abstract description 2
- 239000002609 medium Substances 0.000 description 53
- 210000004027 cell Anatomy 0.000 description 30
- 239000000284 extract Substances 0.000 description 21
- 229920001817 Agar Polymers 0.000 description 19
- 239000008272 agar Substances 0.000 description 19
- 239000011521 glass Substances 0.000 description 16
- 230000012010 growth Effects 0.000 description 13
- 229930013930 alkaloid Natural products 0.000 description 12
- 239000007787 solid Substances 0.000 description 10
- 238000000605 extraction Methods 0.000 description 8
- 239000000203 mixture Substances 0.000 description 8
- 150000003797 alkaloid derivatives Chemical class 0.000 description 7
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 6
- 229910052799 carbon Inorganic materials 0.000 description 6
- 239000001963 growth medium Substances 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- 239000000758 substrate Substances 0.000 description 6
- 239000003630 growth substance Substances 0.000 description 5
- 229940088594 vitamin Drugs 0.000 description 5
- 239000011782 vitamin Substances 0.000 description 5
- 235000013343 vitamin Nutrition 0.000 description 5
- 229930003231 vitamin Natural products 0.000 description 5
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 4
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 4
- 238000009792 diffusion process Methods 0.000 description 4
- QANMHLXAZMSUEX-UHFFFAOYSA-N kinetin Chemical compound N=1C=NC=2N=CNC=2C=1NCC1=CC=CO1 QANMHLXAZMSUEX-UHFFFAOYSA-N 0.000 description 4
- 239000008101 lactose Substances 0.000 description 4
- 244000005700 microbiome Species 0.000 description 4
- 229910052760 oxygen Inorganic materials 0.000 description 4
- 239000001301 oxygen Substances 0.000 description 4
- 239000002689 soil Substances 0.000 description 4
- 150000003722 vitamin derivatives Chemical class 0.000 description 4
- OVSKIKFHRZPJSS-UHFFFAOYSA-N 2,4-D Chemical compound OC(=O)COC1=CC=C(Cl)C=C1Cl OVSKIKFHRZPJSS-UHFFFAOYSA-N 0.000 description 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 229910021578 Iron(III) chloride Inorganic materials 0.000 description 3
- FAIXYKHYOGVFKA-UHFFFAOYSA-N Kinetin Natural products N=1C=NC=2N=CNC=2C=1N(C)C1=CC=CO1 FAIXYKHYOGVFKA-UHFFFAOYSA-N 0.000 description 3
- 230000001851 biosynthetic effect Effects 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 239000000470 constituent Substances 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 229910052742 iron Inorganic materials 0.000 description 3
- 229960001669 kinetin Drugs 0.000 description 3
- 230000000877 morphologic effect Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- -1 basic chemistry Substances 0.000 description 2
- 238000010924 continuous production Methods 0.000 description 2
- 230000004069 differentiation Effects 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- 230000003100 immobilizing effect Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 description 2
- VVQQKXATELLTFX-UHFFFAOYSA-N n-(furan-2-ylmethyl)-7h-purin-2-amine Chemical compound N=1C=C2NC=NC2=NC=1NCC1=CC=CO1 VVQQKXATELLTFX-UHFFFAOYSA-N 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 2
- 239000000376 reactant Substances 0.000 description 2
- 239000005631 2,4-Dichlorophenoxyacetic acid Substances 0.000 description 1
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 1
- 239000002028 Biomass Substances 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- 101150114117 EGR1 gene Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 235000019687 Lamb Nutrition 0.000 description 1
- 240000004658 Medicago sativa Species 0.000 description 1
- 235000010624 Medicago sativa Nutrition 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 241000208422 Rhododendron Species 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- 244000181025 Rosa gallica Species 0.000 description 1
- JZRWCGZRTZMZEH-UHFFFAOYSA-N Thiamine Natural products CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N acetic acid Substances CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 229940072056 alginate Drugs 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 description 1
- 230000003698 anagen phase Effects 0.000 description 1
- 230000002927 anti-mitotic effect Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 238000006065 biodegradation reaction Methods 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 229920001429 chelating resin Polymers 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229930002875 chlorophyll Natural products 0.000 description 1
- 235000019804 chlorophyll Nutrition 0.000 description 1
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 description 1
- 230000002860 competitive effect Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000012136 culture method Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 235000003891 ferrous sulphate Nutrition 0.000 description 1
- 239000011790 ferrous sulphate Substances 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 229930182830 galactose Natural products 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 210000001822 immobilized cell Anatomy 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- 229960000367 inositol Drugs 0.000 description 1
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 1
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 1
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 1
- 150000002597 lactoses Chemical class 0.000 description 1
- 239000010808 liquid waste Substances 0.000 description 1
- 239000005445 natural material Substances 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 235000021231 nutrient uptake Nutrition 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229930010796 primary metabolite Natural products 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 235000008160 pyridoxine Nutrition 0.000 description 1
- 239000011677 pyridoxine Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 229930000044 secondary metabolite Natural products 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- 239000011721 thiamine Substances 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/58—Reaction vessels connected in series or in parallel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/04—Plant cells or tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2468—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/91—Cell lines ; Processes using cell lines
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/813—Continuous fermentation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Clinical Laboratory Science (AREA)
- Sustainable Development (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8022538 | 1980-10-22 | ||
| FR8022538A FR2492404A1 (fr) | 1980-10-22 | 1980-10-22 | Procede de production ou de biotransformation de metabolites par des cellules vegetales in vitro |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5799191A JPS5799191A (en) | 1982-06-19 |
| JPS603830B2 true JPS603830B2 (ja) | 1985-01-30 |
Family
ID=9247172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP56169391A Expired JPS603830B2 (ja) | 1980-10-22 | 1981-10-21 | インビトロでの植物細胞の培養法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5030573A (enExample) |
| EP (1) | EP0050562B1 (enExample) |
| JP (1) | JPS603830B2 (enExample) |
| AT (1) | ATE6871T1 (enExample) |
| CA (1) | CA1172587A (enExample) |
| DE (1) | DE3162902D1 (enExample) |
| FR (1) | FR2492404A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0071999B1 (en) * | 1981-08-11 | 1986-03-26 | Mitsui Petrochemical Industries, Ltd. | Method for producing secondary metabolites of plants |
| JPS58201982A (ja) * | 1982-05-19 | 1983-11-25 | Yoshiatsu Miura | ビンブラスチン高生産能を有する植物組織培養物およびその生産方法 |
| CH663422A5 (de) * | 1982-05-27 | 1987-12-15 | Chemap Ag | Verfahren und fermenter zur zuechtung von gewebezellen. |
| HU190751B (en) * | 1984-01-16 | 1986-11-28 | Mta Szegedi Biologiai Koezpont | Process for producing mixotroph tissue-cultures and herbicide-resisting plants |
| JPH0822224B2 (ja) * | 1987-02-09 | 1996-03-06 | 三井石油化学工業株式会社 | 植物の組織培養方法 |
| DE3855758T2 (de) * | 1987-02-26 | 1997-07-31 | Bio Polymers Pty Ltd | Substanz aus pflanzlichem gummi und ihre verwendung in lebensmitteln |
| US5296245A (en) * | 1987-02-26 | 1994-03-22 | Bio Polymers Pty. Ltd. | Plant gum material and use thereof in food products |
| GB8907136D0 (en) * | 1989-03-30 | 1989-05-10 | Broby Haldane A P | A novel process for the production of the idolizine alkaloids with proven antiviral and anti-retroviral activity from plant cell suspension cultures of ca |
| GB8926286D0 (en) * | 1989-11-21 | 1990-01-10 | Novalal Ltd | The production of enzymes from continuous plant cell suspension culture |
| US6271001B1 (en) | 1995-03-23 | 2001-08-07 | Bio Polymers Pty. Ltd. | Cultured plant cell gums for food, pharmaceutical, cosmetic and industrial applications |
| AU1974497A (en) * | 1996-02-22 | 1997-09-10 | Vivorx Pharmaceuticals, Inc. | Method for growing plant cells in liquid suspension cultures, and chemotherapeutic agents derived from plants |
| US6589780B2 (en) | 2000-12-15 | 2003-07-08 | Council Of Scientific And Industrial Research | Bio-reactor for enhancing the biomass yield of plant organs |
| US9862923B2 (en) | 2010-03-26 | 2018-01-09 | Philip Morris Usa Inc. | Cultured tobacco cells as a matrix for consumable products |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2975553A (en) * | 1957-08-23 | 1961-03-21 | Nat Res Dev | Apparatus for culture of biological cells and tissues |
| SE371208B (enExample) * | 1966-10-06 | 1974-11-11 | Sanraku Ocean Co | |
| GB1204486A (en) * | 1966-12-09 | 1970-09-09 | Boots Pure Drug Co Ltd | Fermentation processes |
| FR2300131A1 (fr) * | 1975-02-04 | 1976-09-03 | Synthelabo | Production d'alcaloides par culture " in vitro " de cellules de vinca minor. l. |
| IL49726A (en) * | 1976-06-06 | 1979-09-30 | Yeda Res & Dev | Production of glycerol from algae |
| DE2726313C3 (de) * | 1977-06-10 | 1980-02-07 | Battelle-Institut E.V., 6000 Frankfurt | Verfahren zur in-vitro-Biosynthese von Hormonen, insbesondere von Insulin |
| US4220725A (en) * | 1978-04-03 | 1980-09-02 | United States Of America | Capillary cell culture device |
| CA1134764A (en) * | 1979-03-21 | 1982-11-02 | Wolfgang W.G. Kurz | Producing codeine from papaver cell cultures |
| GB2025959B (en) * | 1979-07-17 | 1982-10-13 | Gallaher Ltd | Preparing nicotine by culturing a nicotiana strain |
-
1980
- 1980-10-22 FR FR8022538A patent/FR2492404A1/fr active Granted
-
1981
- 1981-10-15 AT AT81401605T patent/ATE6871T1/de not_active IP Right Cessation
- 1981-10-15 EP EP81401605A patent/EP0050562B1/fr not_active Expired
- 1981-10-15 DE DE8181401605T patent/DE3162902D1/de not_active Expired
- 1981-10-21 JP JP56169391A patent/JPS603830B2/ja not_active Expired
- 1981-10-21 CA CA000388426A patent/CA1172587A/en not_active Expired
-
1987
- 1987-01-15 US US07/006,307 patent/US5030573A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5799191A (en) | 1982-06-19 |
| FR2492404A1 (fr) | 1982-04-23 |
| FR2492404B1 (enExample) | 1984-12-07 |
| DE3162902D1 (en) | 1984-05-03 |
| EP0050562A1 (fr) | 1982-04-28 |
| ATE6871T1 (de) | 1984-04-15 |
| CA1172587A (en) | 1984-08-14 |
| EP0050562B1 (fr) | 1984-03-28 |
| US5030573A (en) | 1991-07-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Min et al. | Production of tropane alkaloids by small-scale bubble column bioreactor cultures of Scopolia parviflora adventitious roots | |
| CA2100268A1 (en) | Method for culturing and transforming human stem cell-containing compositions | |
| McKelvey et al. | Growth of plant root cultures in liquid‐and gas‐dispersed reactor environments | |
| JPS603830B2 (ja) | インビトロでの植物細胞の培養法 | |
| Jianfeng et al. | Suspension culture of compact callus aggregate of Rhodiola sachalinensis for improved salidroside production | |
| WO2017217116A1 (ja) | 凝集能を有した新微細藻類 | |
| Liu et al. | Development of a nutrient mist bioreactor for growth of hairy roots | |
| Martinez et al. | Characteristics of batch suspension cultures of preconditioned Coleus blumei cells: sucrose effect | |
| CN114907982B (zh) | 小球藻突变株及其高密度异养培养方法和应用 | |
| Park et al. | Production of sanguinarine by suspension culture of Papayer somniferum in bioreactors | |
| Chen et al. | In vitro production of alfalfa somatic embryos in fermentation systems | |
| Payne et al. | Bioreactor considerations for secondary metabolite production from plant cell tissue culture: indole alkaloids from Catharanthus roseus | |
| US20090098619A1 (en) | Method of producing liquid and powered mushroom beta-glucan | |
| Mori et al. | Growth behavior of immobilized acetic acid bacteria | |
| Shuler et al. | Prospects and problems in the large scale production of metabolites from plant cell tissue cultures | |
| Takayama | Bioreactors for plant cell tissue and organ cultures | |
| EP0009319A1 (en) | Higher plant cell culture | |
| Kreis et al. | Two-stage cultivation of Digitalis lanata cells: semicontinuous production of deacetyllanatoside C in 20-litre airlift bioreactors | |
| CN114058514B (zh) | 一种利用海洋绿藻青岛大扁藻积累淀粉的方法 | |
| Yu et al. | The accumulation of isocamptothecin A and B in suspension cell culture of Camptotheca acuminata | |
| KR920008366B1 (ko) | 유기용매첨가와세포고정화를이용한식물세포배양에서의시코닌생산방법 | |
| Yukimune et al. | Increase of scopolamine production by high density culture of Duboisia myoporoides roots | |
| Weathers et al. | Recovery of secondary metabolites with minimal loss of cell viability | |
| AU599947B2 (en) | Method for cultivating microorganisms, particularly of the frankia group and preparation of bacterial inoculums | |
| KR101058246B1 (ko) | 코엔자임 ｑ10 생성능을 가지는 로도박터 스페어로이즈를 이용한 코엔자임 ｑ10의 대량생산 방법 |