JPS6036422B2 - プロスタグランジン類似化合物及びその製造方法 - Google Patents

プロスタグランジン類似化合物及びその製造方法

Info

Publication number
JPS6036422B2
JPS6036422B2 JP54008904A JP890479A JPS6036422B2 JP S6036422 B2 JPS6036422 B2 JP S6036422B2 JP 54008904 A JP54008904 A JP 54008904A JP 890479 A JP890479 A JP 890479A JP S6036422 B2 JPS6036422 B2 JP S6036422B2
Authority
JP
Japan
Prior art keywords
trans
compound
general formula
acid
dihydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP54008904A
Other languages
English (en)
Japanese (ja)
Other versions
JPS55100360A (en
Inventor
正樹 林
貞彦 井口
任功 岡田
晃義 川崎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority to JP54008904A priority Critical patent/JPS6036422B2/ja
Priority to US06/114,804 priority patent/US4294849A/en
Priority to GB8002617A priority patent/GB2041368B/en
Priority to DE3002677A priority patent/DE3002677C2/de
Priority to IT19486/80A priority patent/IT1129720B/it
Priority to FR8001747A priority patent/FR2447375A1/fr
Priority to CH67480A priority patent/CH644101A5/fr
Publication of JPS55100360A publication Critical patent/JPS55100360A/ja
Publication of JPS6036422B2 publication Critical patent/JPS6036422B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP54008904A 1979-01-29 1979-01-29 プロスタグランジン類似化合物及びその製造方法 Expired JPS6036422B2 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP54008904A JPS6036422B2 (ja) 1979-01-29 1979-01-29 プロスタグランジン類似化合物及びその製造方法
US06/114,804 US4294849A (en) 1979-01-29 1980-01-24 Prostaglandin analogues
GB8002617A GB2041368B (en) 1979-01-29 1980-01-25 Prostaglandin analogues
DE3002677A DE3002677C2 (de) 1979-01-29 1980-01-25 Prostaglandin-analoge, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
IT19486/80A IT1129720B (it) 1979-01-29 1980-01-25 Anaologhi delle prostaglandine
FR8001747A FR2447375A1 (fr) 1979-01-29 1980-01-28 Analogues de la prostaglandine e1 et compositions pharmaceutiques les contenant
CH67480A CH644101A5 (fr) 1979-01-29 1980-01-28 Analogues de la prostaglandine e(1) et compositions pharmaceutiques les contenant.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP54008904A JPS6036422B2 (ja) 1979-01-29 1979-01-29 プロスタグランジン類似化合物及びその製造方法

Publications (2)

Publication Number Publication Date
JPS55100360A JPS55100360A (en) 1980-07-31
JPS6036422B2 true JPS6036422B2 (ja) 1985-08-20

Family

ID=11705653

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54008904A Expired JPS6036422B2 (ja) 1979-01-29 1979-01-29 プロスタグランジン類似化合物及びその製造方法

Country Status (7)

Country Link
US (1) US4294849A (OSRAM)
JP (1) JPS6036422B2 (OSRAM)
CH (1) CH644101A5 (OSRAM)
DE (1) DE3002677C2 (OSRAM)
FR (1) FR2447375A1 (OSRAM)
GB (1) GB2041368B (OSRAM)
IT (1) IT1129720B (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017195762A1 (ja) 2016-05-09 2017-11-16 旭硝子株式会社 新規なプロスタグランジン誘導体
WO2019087948A1 (ja) 2017-10-31 2019-05-09 Ａｇｃ株式会社 プロスタグランジン誘導体の製造方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1215975A (en) * 1981-11-02 1986-12-30 Paul W. Collins Process for preparing delta 2,3 and delta 3,4 prostaglandins
US20090252807A1 (en) * 2005-04-13 2009-10-08 Elan Pharma International Limited Nanoparticulate and Controlled Release Compositions Comprising Prostaglandin Derivatives
RU2420316C2 (ru) 2005-06-03 2011-06-10 Оно Фармасьютикал Ко., Лтд. Агент для регенерации и/или защиты нервов
CN102875586A (zh) * 2011-07-11 2013-01-16 上海天伟生物制药有限公司 一种利马前列素关键中间体的制备方法
WO2014040457A1 (zh) * 2012-09-13 2014-03-20 上海源力生物技术有限公司 一种制备利马前列素的中间体、其制备方法以及通过其制备利马前列素的方法
CN105985371B (zh) * 2015-02-11 2019-06-18 常州博海威医药科技股份有限公司 制备利马前列腺素的关键中间体及其应用
CN105985370B (zh) * 2015-02-11 2019-06-18 常州博海威医药科技股份有限公司 制备利马前列腺素的关键中间体及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931296A (en) * 1972-12-29 1976-01-06 Masaki Hayashi Trans-Δ2 -prostaglandins

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017195762A1 (ja) 2016-05-09 2017-11-16 旭硝子株式会社 新規なプロスタグランジン誘導体
WO2019087948A1 (ja) 2017-10-31 2019-05-09 Ａｇｃ株式会社 プロスタグランジン誘導体の製造方法

Also Published As

Publication number Publication date
IT1129720B (it) 1986-06-11
GB2041368A (en) 1980-09-10
FR2447375A1 (fr) 1980-08-22
US4294849A (en) 1981-10-13
CH644101A5 (fr) 1984-07-13
JPS55100360A (en) 1980-07-31
IT8019486A0 (it) 1980-01-25
FR2447375B1 (OSRAM) 1983-11-18
DE3002677C2 (de) 1986-03-06
GB2041368B (en) 1982-12-01
DE3002677A1 (de) 1980-08-07

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