JPS6024789B2 - ５−フルオロウラシル誘導体化合物 - Google Patents

５−フルオロウラシル誘導体化合物

Info

Publication number
JPS6024789B2
JPS6024789B2 JP51104928A JP10492876A JPS6024789B2 JP S6024789 B2 JPS6024789 B2 JP S6024789B2 JP 51104928 A JP51104928 A JP 51104928A JP 10492876 A JP10492876 A JP 10492876A JP S6024789 B2 JPS6024789 B2 JP S6024789B2
Authority
JP
Japan
Prior art keywords
fluorouracil
compound according
group
day
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP51104928A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5331674A (en
Inventor
昌庸 黒野
芳紀 酒井
宏 横浜
健 千葉
節郎 藤井
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority to JP51104928A priority Critical patent/JPS6024789B2/ja
Priority to GB7736781A priority patent/GB1542053A/en
Priority to FR7726853A priority patent/FR2363562A1/fr
Publication of JPS5331674A publication Critical patent/JPS5331674A/ja
Publication of JPS6024789B2 publication Critical patent/JPS6024789B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP51104928A 1976-09-03 1976-09-03 ５−フルオロウラシル誘導体化合物 Expired JPS6024789B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP51104928A JPS6024789B2 (ja) 1976-09-03 1976-09-03 ５−フルオロウラシル誘導体化合物
GB7736781A GB1542053A (en) 1976-09-03 1977-09-02 5-fluorouracil derivatives
FR7726853A FR2363562A1 (fr) 1976-09-03 1977-09-05 Nouveaux derives du 5-fluorouracile, utiles notamment comme agents anticancereux et leur procede de preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51104928A JPS6024789B2 (ja) 1976-09-03 1976-09-03 ５−フルオロウラシル誘導体化合物

Publications (2)

Publication Number Publication Date
JPS5331674A JPS5331674A (en) 1978-03-25
JPS6024789B2 true JPS6024789B2 (ja) 1985-06-14

Family

ID=14393750

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51104928A Expired JPS6024789B2 (ja) 1976-09-03 1976-09-03 ５−フルオロウラシル誘導体化合物

Country Status (3)

Country Link
JP (1) JPS6024789B2 (enExample)
FR (1) FR2363562A1 (enExample)
GB (1) GB1542053A (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5587721A (en) * 1978-12-26 1980-07-02 Ono Pharmaceut Co Ltd Anti-tumor agent
GB2085002B (en) * 1980-10-01 1984-08-08 Beecham Group Ltd 5-fluoro-uracil derivatives as anti-tumour agents
DK197486A (da) * 1986-04-30 1987-10-31 Ferring Farma Lab 5-fluoruracilprodug
GB201511125D0 (en) * 2015-06-24 2015-08-05 Cambridge Entpr Ltd Amorhous metal-organic frameworks

Also Published As

Publication number Publication date
FR2363562B1 (enExample) 1981-07-24
GB1542053A (en) 1979-03-14
JPS5331674A (en) 1978-03-25
FR2363562A1 (fr) 1978-03-31

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