FR2363562A1 - Nouveaux derives du 5-fluorouracile, utiles notamment comme agents anticancereux et leur procede de preparation - Google Patents

Nouveaux derives du 5-fluorouracile, utiles notamment comme agents anticancereux et leur procede de preparation

Info

Publication number
FR2363562A1
FR2363562A1 FR7726853A FR7726853A FR2363562A1 FR 2363562 A1 FR2363562 A1 FR 2363562A1 FR 7726853 A FR7726853 A FR 7726853A FR 7726853 A FR7726853 A FR 7726853A FR 2363562 A1 FR2363562 A1 FR 2363562A1
Authority
FR
France
Prior art keywords
fluorouracil
useful
preparation process
cancer agents
new derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7726853A
Other languages
English (en)
Other versions
FR2363562B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Publication of FR2363562A1 publication Critical patent/FR2363562A1/fr
Application granted granted Critical
Publication of FR2363562B1 publication Critical patent/FR2363562B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Les médicaments selon l'invention répondent à la formule :
FR7726853A 1976-09-03 1977-09-05 Nouveaux derives du 5-fluorouracile, utiles notamment comme agents anticancereux et leur procede de preparation Granted FR2363562A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51104928A JPS6024789B2 (ja) 1976-09-03 1976-09-03 ５−フルオロウラシル誘導体化合物

Publications (2)

Publication Number Publication Date
FR2363562A1 true FR2363562A1 (fr) 1978-03-31
FR2363562B1 FR2363562B1 (fr) 1981-07-24

Family

ID=14393750

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7726853A Granted FR2363562A1 (fr) 1976-09-03 1977-09-05 Nouveaux derives du 5-fluorouracile, utiles notamment comme agents anticancereux et leur procede de preparation

Country Status (3)

Country Link
JP (1) JPS6024789B2 (fr)
FR (1) FR2363562A1 (fr)
GB (1) GB1542053A (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5587721A (en) * 1978-12-26 1980-07-02 Ono Pharmaceut Co Ltd Anti-tumor agent
GB2085002B (en) * 1980-10-01 1984-08-08 Beecham Group Ltd 5-fluoro-uracil derivatives as anti-tumour agents
DK197486A (da) * 1986-04-30 1987-10-31 Ferring Farma Lab 5-fluoruracilprodug
GB201511125D0 (en) * 2015-06-24 2015-08-05 Cambridge Entpr Ltd Amorhous metal-organic frameworks

Also Published As

Publication number Publication date
FR2363562B1 (fr) 1981-07-24
JPS6024789B2 (ja) 1985-06-14
GB1542053A (en) 1979-03-14
JPS5331674A (en) 1978-03-25

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Legal Events

Date Code Title Description
ST Notification of lapse