JPS60241900A - 新規な第Ｘａ因子活性測定用基質 - Google Patents

新規な第Ｘａ因子活性測定用基質

Info

Publication number
JPS60241900A
JPS60241900A JP59098355A JP9835584A JPS60241900A JP S60241900 A JPS60241900 A JP S60241900A JP 59098355 A JP59098355 A JP 59098355A JP 9835584 A JP9835584 A JP 9835584A JP S60241900 A JPS60241900 A JP S60241900A
Authority
JP
Japan
Prior art keywords
factor
substrate
arg
oha
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59098355A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0411199B2 (enrdf_load_stackoverflow
Inventor
Takeshi Nagasawa
長沢　健
Yoshio Nakamura
中村　善夫
Takeshi Enomoto
榎本　毅
Katsumasa Kuroiwa
黒岩　勝昌
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nitto Boseki Co Ltd
Original Assignee
Nitto Boseki Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitto Boseki Co Ltd filed Critical Nitto Boseki Co Ltd
Priority to JP59098355A priority Critical patent/JPS60241900A/ja
Priority to US06/732,396 priority patent/US4622389A/en
Priority to DE8585105988T priority patent/DE3560635D1/de
Priority to EP85105988A priority patent/EP0170797B1/en
Publication of JPS60241900A publication Critical patent/JPS60241900A/ja
Publication of JPH0411199B2 publication Critical patent/JPH0411199B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96444—Factor X (3.4.21.6)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/802—Chromogenic or luminescent peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
JP59098355A 1984-05-16 1984-05-16 新規な第Ｘａ因子活性測定用基質 Granted JPS60241900A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP59098355A JPS60241900A (ja) 1984-05-16 1984-05-16 新規な第Ｘａ因子活性測定用基質
US06/732,396 US4622389A (en) 1984-05-16 1985-05-09 Novel substrate for determining the activity of blood coagulation factor Xa (Stuart-Prower factor)
DE8585105988T DE3560635D1 (en) 1984-05-16 1985-05-15 Novel substrate for determining the activity of blood coagulation factor xa (stuart-prower factor)
EP85105988A EP0170797B1 (en) 1984-05-16 1985-05-15 Novel substrate for determining the activity of blood coagulation factor xa (stuart-prower factor)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59098355A JPS60241900A (ja) 1984-05-16 1984-05-16 新規な第Ｘａ因子活性測定用基質

Publications (2)

Publication Number Publication Date
JPS60241900A true JPS60241900A (ja) 1985-11-30
JPH0411199B2 JPH0411199B2 (enrdf_load_stackoverflow) 1992-02-27

Family

ID=14217579

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59098355A Granted JPS60241900A (ja) 1984-05-16 1984-05-16 新規な第Ｘａ因子活性測定用基質

Country Status (4)

Country Link
US (1) US4622389A (enrdf_load_stackoverflow)
EP (1) EP0170797B1 (enrdf_load_stackoverflow)
JP (1) JPS60241900A (enrdf_load_stackoverflow)
DE (1) DE3560635D1 (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5627038A (en) * 1989-08-17 1997-05-06 Dade International Inc. Factor IX chromogenic assay

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4851336A (en) * 1985-09-05 1989-07-25 Yin E Thye Composition, kit, and method for assaying heparinano a method for making the composition
US4946775A (en) * 1985-09-05 1990-08-07 Yin E Thye Composition, kit and method for assaying heparin and a method for making the composition
US4948724A (en) * 1985-09-05 1990-08-14 Yin E Thye Composition, kit and method for assaying heparin and a method for making the composition
JPS62126197A (ja) * 1985-11-26 1987-06-08 Nitto Boseki Co Ltd 新規な血漿キニノゲナーゼ測定用化合物
SE8601327D0 (sv) * 1986-03-21 1986-03-21 Kabivitrum Ab Nya peptidderivat
SE461494B (sv) * 1986-03-21 1990-02-19 Thorsman & Co Ab Faestanordning foer en elektrisk kopplingsdosa
US4784940A (en) * 1987-06-26 1988-11-15 Mesa Medical, Inc. Quantitation of cancer procoagulant activity in serum
US5023236A (en) * 1988-04-07 1991-06-11 Corvas, Inc. Factor VII/VIIA active site inhibitors
US5187155A (en) * 1989-06-23 1993-02-16 Board Of Regents, The University Of Texas System Anticoagulant peptides
US5308755A (en) * 1992-06-08 1994-05-03 Research Corporation Technologies, Inc. Method for measuring heparin
NZ261190A (en) 1993-01-29 1997-12-19 Bjorn Dahlback Assaying for functional activity of a blood coagulation component involved in the protein c anticoagulant system (protein c, activated protein c, protein s or anticoagulant factor v)
US6379975B1 (en) 1996-11-27 2002-04-30 T.A.C. Thrombosis And Coagulation Aktiebolag Methods and reagents for determining protein S
NL1006429C2 (nl) * 1997-06-27 1998-12-29 Univ Maastricht Werkwijze voor het bepalen van het heparinegehalte.
US6855509B2 (en) 2000-12-19 2005-02-15 Instrumentation Laboratory Company Protein S functional assay and kit therefor
GB2485590A (en) * 2010-11-22 2012-05-23 Univ Ruprecht Karis Heidelberg Method for detecting at least one direct factor Xa inhibitors
WO2012154272A1 (en) 2011-02-25 2012-11-15 Wellstat Diagnostics, Llc Assays for detecting enzymatic activity
WO2017059060A1 (en) * 2015-09-30 2017-04-06 The Johns Hopkins University Salicylic acid-based polymeric cest contrast agents targeting prostate-specific membrane antigen and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4162941A (en) * 1974-12-05 1979-07-31 Ab Kabi Method for determining a proteolytic enzyme
CA1161432A (en) * 1980-02-12 1984-01-31 Lars G. Svendsen Tripeptide derivatives and their application in assaying enzymes
JPS5856695A (ja) * 1981-09-28 1983-04-04 Nitto Boseki Co Ltd 新規なトロンビン測定用基質
JPS5863399A (ja) * 1981-10-14 1983-04-15 Nitto Boseki Co Ltd 新規なプラスミン測定用基質

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5627038A (en) * 1989-08-17 1997-05-06 Dade International Inc. Factor IX chromogenic assay

Also Published As

Publication number Publication date
JPH0411199B2 (enrdf_load_stackoverflow) 1992-02-27
EP0170797B1 (en) 1987-09-16
EP0170797A1 (en) 1986-02-12
US4622389A (en) 1986-11-11
DE3560635D1 (en) 1987-10-22

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Legal Events

Date Code Title Description
EXPY Cancellation because of completion of term