JPS60190788A - 大豆胚軸からのサポニン成分の抽出・精製法 - Google Patents

Info

Publication number

JPS60190788A

JPS60190788A JP59045152A JP4515284A JPS60190788A JP S60190788 A JPS60190788 A JP S60190788A JP 59045152 A JP59045152 A JP 59045152A JP 4515284 A JP4515284 A JP 4515284A JP S60190788 A JPS60190788 A JP S60190788A

Authority

JP

Japan

Prior art keywords

saponin

solvent

saponin component

extraction

methanol

Prior art date

1984-03-09

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 239000001397 quillaja saponaria molina bark Substances 0.000 title claims abstract description 43
• 229930182490 saponin Natural products 0.000 title claims abstract description 43
• 150000007949 saponins Chemical class 0.000 title claims abstract description 43
• 235000010469 Glycine max Nutrition 0.000 title claims abstract description 34
• 244000068988 Glycine max Species 0.000 title claims abstract description 34
• 238000000605 extraction Methods 0.000 title claims abstract description 10
• 238000000746 purification Methods 0.000 title claims description 6
• OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims abstract description 66
• 239000002904 solvent Substances 0.000 claims abstract description 13
• 239000002994 raw material Substances 0.000 claims abstract description 6
• 238000000034 method Methods 0.000 claims description 21
• 239000000126 substance Substances 0.000 claims description 6
• 238000004519 manufacturing process Methods 0.000 claims description 3
• VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract description 8
• YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract description 6
• 238000010438 heat treatment Methods 0.000 abstract description 3
• LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 32
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
• KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 6
• 239000000203 mixture Substances 0.000 description 5
• RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
• 238000005238 degreasing Methods 0.000 description 3
• 239000000284 extract Substances 0.000 description 3
• 239000000401 methanolic extract Substances 0.000 description 3
• 239000002244 precipitate Substances 0.000 description 3
• PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
• 238000001035 drying Methods 0.000 description 2
• 150000002632 lipids Chemical class 0.000 description 2
• 239000000843 powder Substances 0.000 description 2
• 238000005292 vacuum distillation Methods 0.000 description 2
• 238000005406 washing Methods 0.000 description 2
• DDSDPQHQLNAGLJ-YEBWQKSTSA-N (2z)-6-(2-chlorophenyl)-2-[(4-methylpiperazin-4-ium-1-yl)methylidene]-8-nitro-4h-imidazo[1,2-a][1,4]benzodiazepin-1-one;methanesulfonate Chemical compound CS(O)(=O)=O.C1CN(C)CCN1\C=C/1C(=O)N2C3=CC=C([N+]([O-])=O)C=C3C(C=3C(=CC=CC=3)Cl)=NCC2=N\1 DDSDPQHQLNAGLJ-YEBWQKSTSA-N 0.000 description 1
• NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 1
• BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
• VCUFZILGIRCDQQ-KRWDZBQOSA-N N-[[(5S)-2-oxo-3-(2-oxo-3H-1,3-benzoxazol-6-yl)-1,3-oxazolidin-5-yl]methyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C1O[C@H](CN1C1=CC2=C(NC(O2)=O)C=C1)CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F VCUFZILGIRCDQQ-KRWDZBQOSA-N 0.000 description 1
• 229930187719 Soyasaponin Natural products 0.000 description 1
• -1 aliphatic alcohols Chemical class 0.000 description 1
• 239000003963 antioxidant agent Substances 0.000 description 1
• 230000003078 antioxidant effect Effects 0.000 description 1
• KTUQUZJOVNIKNZ-UHFFFAOYSA-N butan-1-ol;hydrate Chemical compound O.CCCCO KTUQUZJOVNIKNZ-UHFFFAOYSA-N 0.000 description 1
• 238000004821 distillation Methods 0.000 description 1
• 239000012153 distilled water Substances 0.000 description 1
• 238000009826 distribution Methods 0.000 description 1
• 230000000694 effects Effects 0.000 description 1
• 230000001804 emulsifying effect Effects 0.000 description 1
• 238000001914 filtration Methods 0.000 description 1
• 239000012535 impurity Substances 0.000 description 1
• 230000002452 interceptive effect Effects 0.000 description 1
• 239000003456 ion exchange resin Substances 0.000 description 1
• 229920003303 ion-exchange polymer Polymers 0.000 description 1
• 238000003808 methanol extraction Methods 0.000 description 1
• 230000000144 pharmacologic effect Effects 0.000 description 1
• 238000003825 pressing Methods 0.000 description 1
• 239000000047 product Substances 0.000 description 1
• 239000011347 resin Substances 0.000 description 1
• 229920005989 resin Polymers 0.000 description 1
• 238000007873 sieving Methods 0.000 description 1
• 238000000638 solvent extraction Methods 0.000 description 1
• 238000003756 stirring Methods 0.000 description 1
• SFXOHDOEOSCUCT-UHFFFAOYSA-N styrene;hydrochloride Chemical compound Cl.C=CC1=CC=CC=C1 SFXOHDOEOSCUCT-UHFFFAOYSA-N 0.000 description 1

Cited By (3)