JPS60172285A - 新規抗生物質ａｃ−１９７８およびその製造法 - Google Patents
新規抗生物質ａｃ−１９７８およびその製造法Info
- Publication number
- JPS60172285A JPS60172285A JP59028556A JP2855684A JPS60172285A JP S60172285 A JPS60172285 A JP S60172285A JP 59028556 A JP59028556 A JP 59028556A JP 2855684 A JP2855684 A JP 2855684A JP S60172285 A JPS60172285 A JP S60172285A
- Authority
- JP
- Japan
- Prior art keywords
- antibiotic
- reaction
- culture
- methanol
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 238000002360 preparation method Methods 0.000 title abstract 2
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- 239000000126 substance Substances 0.000 claims abstract description 25
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims abstract description 21
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims abstract description 21
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims abstract description 20
- 238000006243 chemical reaction Methods 0.000 claims abstract description 17
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 14
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- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- OVARTBFNCCXQKS-UHFFFAOYSA-N propan-2-one;hydrate Chemical compound O.CC(C)=O OVARTBFNCCXQKS-UHFFFAOYSA-N 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 229940107700 pyruvic acid Drugs 0.000 description 1
- MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 235000019512 sardine Nutrition 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 235000019710 soybean protein Nutrition 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- VABRZWDEEDQLRD-UHFFFAOYSA-N streptomyces antibiotic uk-63052 Chemical compound CN1C(=O)C(N(C)C(=O)C(C)NC(=O)C(COC(=O)C2(C(C2)C)N(C)C2=O)NC(=O)C=3C(=CC4=CC=CC=C4N=3)O)C(SC(C)CC)SCC2N(C)C(=O)C(C)NC(=O)C(NC(=O)C=2C(=CC3=CC=CC=C3N=2)O)COC(=O)C21CC2C VABRZWDEEDQLRD-UHFFFAOYSA-N 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59028556A JPS60172285A (ja) | 1984-02-20 | 1984-02-20 | 新規抗生物質ａｃ−１９７８およびその製造法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59028556A JPS60172285A (ja) | 1984-02-20 | 1984-02-20 | 新規抗生物質ａｃ−１９７８およびその製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS60172285A true JPS60172285A (ja) | 1985-09-05 |
| JPH0372237B2 JPH0372237B2 (enrdf_load_stackoverflow) | 1991-11-18 |
Family
ID=12251919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59028556A Granted JPS60172285A (ja) | 1984-02-20 | 1984-02-20 | 新規抗生物質ａｃ−１９７８およびその製造法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS60172285A (enrdf_load_stackoverflow) |
-
1984
- 1984-02-20 JP JP59028556A patent/JPS60172285A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0372237B2 (enrdf_load_stackoverflow) | 1991-11-18 |
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