JPS60142906A - Acaricide for indoor use - Google Patents

Abstract

PURPOSE:An acaricide for indoor use, obtained by incorporating a specific pyrethroid compound with a synergistic agent therefore and an injurious insect repellent, capable of exhibiting improved acaricidal effect on Tyrophagus dimidiatus, Dermatophagoides farinae and Tarsonemus floricolus, etc., and usable with safety. CONSTITUTION:An acaricide for indoor use obtained by incorporating a compound, expressed by the formula (X is CH3 or Cl), having high insecticidal power and wide insecticidal spectrum and high safety for humans and animals, and used widely for homes and agriculture, i.e. ''Phenothrin (X=CH3) or ''Permethrin'' (X=Cl), with an inexpensive synergistic agent for pyrethroid, e.g. IBTA, S-421 or piperonyl butoxide, exhibiting some acraricidal activity against mites developing in the interior of a house and one or two or more of injurious insect repellents, e.g. ''Deet'' of benzyl benzoate, used widely and practically as a repellent for mosquitoes and flies, as active constituents, adding a carrier or assistant thereto, and used in the form of an emulsion, wettable powder, powder or oil, etc.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention provides a compound represented by the general formula (wherein X represents a methyl group or a chloro atom) or one or two of a pyrethroid synergist and an insect repellent. This invention relates to an indoor acaricide characterized by adding kernels. An extremely wide variety of mites inhabit the earth, such as the citrus spider mite and the two-spot spider mite #It'i, which parasitize plants and cause great damage to agricultural crops. These acaricides for agricultural use have been under development for a long time, and new and promising compounds have recently been discovered one after another.

On the other hand, due to changes in the living environment in recent years, dust mites, dust mites, etc. have appeared in homes, causing not only discomfort but also problems such as allergic breathing and skin rashes.

It was known that organic phosphorus agents such as Sumithion and Diazinon were effective against these indoor mites, but there were obstacles to practical application due to safety and resistance issues for humans and livestock. There is a strong desire to establish a method for extermination.

In view of the above-mentioned current situation, the present inventors continued intensive research with the aim of developing a miticide that can be safely used indoors, and as a result, a pyrethroid compound represented by the general formula (I) (X =
CH3i phenothrin, X=CA'; vermethrin) alone, or in combination with IBTA, S-421, biperonyl ptoxide, cinepirin 222. Cynevirin 50
0. Synergists for pyrethroids such as Riessen 384 and DEET.

One or two pest repellents such as benzyl benzoate
The present invention has been completed by discovering that a composition containing seeds exhibits an extremely high acaricidal effect on white mites, house dust mites, dust mites, and the like.

Incidentally, the pyrethroid of general formula (I) has high insecticidal power and a wide insecticidal spectrum, and is widely used for household and agricultural purposes as a highly safe insecticide.
Its miticidal power against orange spider mites and two-spotted spider mites is extremely weak, and it has been difficult to apply it to mites in general. However, the present inventors believe that there are some ecological differences between mites that live on plants, such as citrus spider mites and red-spotted spider mites, and mites that occur indoors, such as white mites and house dust mites, and have investigated the effects of various compounds on the latter mites. As a result of the study, it was announced that the pyrethroid with the general formula CI has a high acaricidal effect specifically against mites growing indoors, and it has recently been announced that the pyrethroid has excellent acaricidal activity. We discovered that some new pyrethroids are not necessarily effective against mites that grow indoors. Furthermore, the general formula (
Compounds with a cyano group introduced into the benzyl position of the alcohol moiety in I) generally have superior insecticidal and agnicidal activity compared to the original compound, but they have less activity against mites growing indoors. It became clear that the results showed a decrease in

These findings were completely unexpected based on conventional knowledge, and considering that the pyrethroids of general formula (I) are widely used as insecticides that are safe for humans and livestock. , which is extremely useful for developing indoor acaricides. There are two asymmetric carbon atoms in the acid moiety of the compound of general formula (I), and four optical isomers are possible, and each of these or any mixture thereof is of course included in the present invention.

Also, more TA, S-421, biveronyl toxide,
Cinepirin 222. Cynevirin 500° Risen 3
It has become clear that insect repellents such as oyohytito, a synergist for pyrethroids such as No. 84, and benzyl benzoate have some acaricidal effect. It has been confirmed that a composition containing one or two of these exhibits an extremely high acaricidal effect that is more than additive.

There are still many unknowns as to why the pyrethroids of the general formula (I) have a high extermination effect specifically against white mites and dust mites that occur indoors. This is thought to be partially related to the morphological vacancy of spider mites, which are prospirochlear.

Synergists for pyrethroid do not have insecticidal power by themselves, but when used together with pyrethroids, they are known to suppress the metabolic decomposition of pyrethroids in insect bodies and improve their insecticidal power. It itself shows some acaricidal activity against insects, suggesting a difference in the mechanism of action between insects and mites.

Furthermore, the fact that a mixed composition of the pyrethroid of general formula (I) and a pyrethroid synergist exhibits a high synergistic effect has high practical value because the latter is very inexpensive.

DEET, pendyl benzoate, is a compound that is widely used as a repellent for mosquitoes, flies, etc., and it is interesting that it shows acaricidal effects. It can be used as a multipurpose composition including extermination of mites.

Although it is possible to apply the above-mentioned active ingredients as they are to the acaricide of the present invention, it is usually preferably prepared in various forms such as emulsions, wettable powders, etc., depending on the purpose of use, using suitable carriers and other compounding agents. Used as powder, oil, aerosol, etc. Examples of liquid carriers include water, alcohols (
Methyl alcohol, ethyl alcohol 1. ethylene glycol, etc.), ketones (acetone, methyl ethyl ketone, cyclohexanone, etc.), ethers (ethyl ether, dioxane, cellosolves, etc.), aliphatic hydrocarbons (gasoline, glocine, kerosene, etc.), aromatic hydrocarbons (
benzene, toluene, xylene, methylnaphthalene, etc.)
, halogenated hydrocarbons (dichloromethane, trichlorobenzene, etc.), esters, acid amides, nitriles and the like are suitable, and one type or a mixture of two or more of these may be used.

Suitable solid carriers include, for example, clays (hexagonal phosphorus, bentonite #l), talcs, silicas, alumina powder, activated carbons, vegetable powders, and one or more of these. A mixture is used. Further, as compounding agents, emulsifiers, dispersants, spreading agents, penetrants, surfactants, stabilizers, etc. are suitable, and one type or a mixture of two or more of these can be used.

Alternatively, other unfamiliar acaricides, antioxidants, insecticides, fungicides, fungicides, flavorings, and coloring agents that inhibit the activity of the active ingredient of the present invention may be added.

The amount of the active ingredient in the acaricide of the present invention and its usage amount are appropriately determined depending on the dosage form, application target, application method, application location, etc. For example, it can be used to exterminate mites that live on tatami mats, such as Kona mites.
0.11 ng or more preferably 1 rne per ri 1 tatami
~2 g of pyrethroid compound of general formula (I) are used.

Note that tatami mats are inhabited by insect pests such as grass beetles and wasps, and the composition of the present invention can also exterminate these pests at the same time. However, the present invention is not limited to the following examples unless it exceeds the gist thereof.

Test Example 1 10 g of powdered feed treated with the test compound and 10 g of powdered feed containing approximately 2,500 woolly mites were mixed to obtain a test powdered feed of a predetermined concentration. Each 5 g of this powdered feed was placed in a petri dish with a diameter of 6a and placed at a temperature of 25° CsR degree of 75%. One week and two weeks later, the number of surviving mites in 0.2 g of feed was determined by the saturated saline suspension method, and the reproduction suppression rate was calculated according to the formula below. The test was repeated three times for each concentration.

Note that the symbols a) and b) in the general formula (I) of the test compound
.

Q) and d) each represent the following meanings.

a); Acid part di-cis/1rans form b); Acid part d-cis/1rans form c); Acid part di-ai
s form d); acid moiety d -trans form N Based on the above results, the composition of the present invention, that is, the compound of general formula (I), or one or two of a pyrethroid synergist and an insect repellent were added to it. The compositions (test compound examples 1 to 5) showed excellent acaricidal effects. On the other hand, the activity of other pyrethroid compounds (control compounds (Al (B), (C)) and pyrethroid synergists or pest repellents alone was very low, confirming the usefulness of the composition of the present invention. .

Example 1 TA5. After dissolving Og in refined kerosene, filling it into an aerosol container and attaching a pulp part, a propellant is passed through the pulp part. IJ! I filled it up and got an aerosol.

In a 6-tatami room where woolly mites were breeding, approximately 1/4 of the above-prepared aerosol was injected into the tatami area, and when the population density of mites was examined one week later, it was found to have decreased to less than 5%.

Example 2 Permethrin O, SG, 1.0 part of benzyl benzoate, and 98.5 parts of clay were thoroughly ground and mixed to obtain a powder.

The above powder preparation was sprayed on a 10σ square carpet inoculated with approximately 300 P. elegans mites at a rate of 20 g per carpet, and two days later, the number of surviving P. elegans was found to be less than 5.

Procedural amendment (voluntary) October 3L, 1981 1. Display of incident Chowa 1988 Patent Application No. 245990 8. Person who makes corrections 4. Agent 7. Contents of correction

Claims (1)

[Claims] (1) For indoor use, characterized by adding one or two of a pyrethroid synergist and an insect repellent to a compound represented by the general formula (in the formula, or a methyl group or a chloro atom); Acaricide.