JPH0475201B2 - - Google Patents

Description

[Detailed description of the invention]

The present invention relates to an indoor acaricide characterized by containing β-butoxy-β'-rhodan diethyl ether or β-rhodan ethyl lauric acid ester. An extremely wide variety of mites inhabit the earth, and for example, citrus spider mites, two-spotted spider mites, etc. that parasitize plants cause great damage to agricultural crops. Acaricides aimed at these agricultural applications have been under development for a long time, and new promising compounds have recently been discovered one after another. On the other hand, due to changes in the living environment in recent years, dust mites, dust mites, brown dust mites, dust mites, dust mites, claw mites, sugar mites, etc. have appeared in homes, and they not only cause discomfort, but also cause allergic asthma and skin rashes. It's causing problems. It has been known that organic phosphorus agents such as Sumithion and Diazinon are effective against these indoor mites, but there are obstacles to practical application due to safety and resistance issues for humans and livestock, and accurate extermination is difficult. There was an urgent need to establish a method. In view of the above-mentioned current situation, the present inventors continued intensive research with the aim of developing a miticide that can be safely used indoors, and as a result, we found that β-butoxy-β'-rhodan diethyl ether or β-rhodan ethyl lauric acid ester. The present invention has been completed by discovering that the composition containing the present invention exhibits an extremely high acaricidal effect on powder mites, house dust mites, dust mites, and the like. β-Butoxy-β'-rhodan diethyl ether or β-rhodan ethyl laurate used in the present invention is a compound known as a synergist for pyrethroids. That is, β-butoxy-
β'-Rhodan diethyl ether or β-lauric acid
Rodan ethyl ester itself does not have insecticidal power, but when used together with pyrethroids, it is known to suppress the metabolic decomposition of pyrethroid in the insect body and improve its insecticidal power. Surprisingly, it itself showed extremely high acaricidal activity, suggesting a difference in the mechanism of action between insects and mites. These pyrethroid synergists have very low toxicity to humans and livestock and are extremely inexpensive, so they are extremely useful in the development of indoor acaricides. In particular, Dermatophagoides mites, which occur on carpets, are thought to be the cause of allergic diseases and human infections.
The knowledge that pyrethroid synergists are effective against these is of great health and medical significance. The present invention also includes phenothrin, permethrin, resmethrin, 3'-phenoxybenzyl,
pyrethroid compounds such as 2,2,3,3-tetramethylcyclopropanecarboxylate,
Other pyrethroid synergists such as IBTA, S-421, piperonyl butoxide, cinepirin-222, cinepirin 500, or pest repellents such as DEET, benzyl benzoate, and toxicity are not a problem. Organic phosphorus insecticides such as Sumithion and Diazinon, or carbamate insecticides such as Tsumaside and Meopal,
Of course, it is also possible to use it in combination with other insecticides, fungicides, fungicides, etc., and the composition can be used as a multipurpose composition. Although it is possible to apply the above-mentioned active ingredients as they are to the acaricide of the present invention, it is usually preferably prepared in various forms such as emulsions, wettable powders, etc., depending on the purpose of use, using suitable carriers and other compounding agents. powder, oil,
Used as an aerosol agent, etc. Suitable liquid carriers include solvents such as water, alcohols, ketones, ethers, aliphatic hydrocarbons, halogenated hydrocarbons, esters, and acid amides; Mixtures of two or more are used. In addition, suitable solid carriers include, for example, clays (kaolin, bentonite, etc.), talcs, silicas, alumina powder, activated carbons, vegetable powders, etc., and one or a mixture of two or more of these is suitable. used. Further, as compounding agents, emulsifiers, dispersants, spreading agents, penetrants, surfactants, stabilizers, etc. are suitable, and one type or a mixture of two or more of these can be used. The amount of the active ingredient in the acaricide of the present invention and its usage amount are appropriately determined depending on the dosage form, application target, application method, application location, etc. For example, to exterminate mites living on tatami mats such as mites, 0.1 mg or more, preferably 1 mg to 5 g of the β-butoxy-β'-rhodan diethyl ether or β-rhodan ethyl lauric acid ester is used per 1 tatami mat. In addition, when treating tatami mats at home, an aerosol agent is easy to use.
It is effective to treat the composition under the tatami surface and between the tatami mats, and it is of course also possible to apply the composition of the present invention when manufacturing tatami mats. In addition, 1 m ² can be used to exterminate mites, etc. that live in carpets.
It is preferable to apply 0.5 mg to 5 g of the synergist for pyrethroid of the present invention per dose, and it can be easily used in the form of an aerosol, powder, etc., and is excellent in terms of effectiveness and safety. In addition, when the emulsion is treated during carpet production, it is also possible to use the emulsion mixed with the backing material of the carpet. Additionally, fumigants are useful for treating an entire room at once. EXAMPLES Hereinafter, the present invention will be explained in more detail with reference to examples, but the present invention is not limited to the following examples unless the gist thereof is exceeded. Test Example 1 10g of powdered feed treated with the test compound and 10g of powdered feed containing approximately 2000 woolly mites were mixed,
A test powder feed of a predetermined concentration was obtained. This powdered feed
Place 5g each in a 6cm diameter chalet and heat at 25℃.
It was placed under conditions of 75% humidity. One week and two weeks later, the number of surviving mites in 0.2 g of feed was determined by the saturated saline suspension method, and the reproduction suppression rate was calculated according to the formula below. The test was repeated three times for each concentration. Reproduction suppression rate = number of mites in untreated area -
Number of mites in treated area/number of mites in untreated area x 100 Note that the codes A and B in the sample pyrethroid synergist
represent the following meanings. A: β-butoxy-β'-rhodan diethyl ether B: lauric acid β-rhodan ethyl ester

[Table] From the above results, it was found that the composition of the present invention, that is, the acaricide containing β-butoxy-β'-rhodan diethyl ether or β-rhodan ethyl lauric acid, or the composition using this in combination with other drugs ( Co-test compounds 1 to 5) showed excellent acaricidal effects. On the other hand, the activity of other pyrethroid synergists alone (control compounds; test compound examples 6 to 7) was very low;
The usefulness of the composition of the present invention was confirmed. Test Example 2 10g of powdered feed treated with the test compound and approx.
10 g of a powdered feed containing 100.000 mites was mixed to obtain a test powdered feed with a predetermined concentration. A test was conducted in the same manner as in Test Example 1 using 5 g of this powdered feed, and the reproduction suppression rate was determined after 1 week and 2 weeks.

【table】

[Table] From the above results, the composition of the present invention exhibits a higher acaricidal effect against Dermatophagoides nigricans than Sumithion, an organic phosphorus agent that has been considered to be effective in the past;
Cinepirin, a synergist for other pyrethroids
The activity of 222 is very low, and the activity of β-butoxy-β'-rhodan diethyl ether or lauric acid β-
- It was confirmed that rhodan ethyl ester is highly effective against specifically indoor mites. Example 1 β-Butoxy-β'-rhodan diethyl ether
Dissolve 2.0g and 1.0g of resmethrin in refined kerosene,
After filling the aerosol container and attaching the valve part, the propellant was filled under pressure through the valve part to obtain an aerosol. In a 6-tatami room where woolly mites were breeding, approximately 1/4 of the above-prepared aerosol was injected into the tatami area, and the density of mites was examined one week later and found to have decreased to less than 5%. Example 2 1.0 part of lauric acid β-rodane ethyl ester,
0.5 parts permethrin, 1.0 part S-421 and 97.5 parts clay
The mixture was thoroughly ground and mixed to obtain a powder. The above-mentioned powder preparation was applied to a 10 cm square carpet inoculated with about 400 Dermatophagoides nigricans at a rate of 20 g per 1 m ² . Two days later, the number of surviving Dermatophagoides nigra was less than 5.

Claims (1)

[Claims] 1. An indoor acaricide characterized by containing β-butoxy-β'-rhodan diethyl ether or β-rhodan ethyl lauric acid ester.