JPH08225417A - Aerosol agent for controlling house tick - Google Patents

Abstract

PURPOSE: To provide an aerosol agent having excel lent house tick controllability, safely usable in the interior of house, suitable for controlling acarids in a carpet, comprising phenothrin or phenothrin and a synergist for pyrethroid or a propellant for insect pests. CONSTITUTION: This aerosol agent comprises (A) a pyrethroid-based compound phenothrin of the formula or (B) the component A and octachlorodipropyl ether, N-(2-ethylhexyl)-1-isopropyl-4-methylbicyclo[2,2,2]oct-5-ene-2,3-dicar boximide, N-(2-ethylhexyl)-bicyclo[2,2,1]hept-5-ene-2,3-dicarboximide, piperonyl butoxide, isobornyl thiocyanoacetate, 2-butoxy-2'-thiocyanoethyl ether, N,N-diethyl-m- toluamide or benzyl benzoate.

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to formula (I):

Embedded image (Phenothrin) or a compound represented by formula (I) and one or two synergists for pyrethroids and pest repellents, and an aerosol agent for indoor mite control for carpet treatment.

[0002]

2. Description of the Related Art A great variety of mites live on the earth, and, for example, citrus red mite and spider mites parasitic on plants cause great damage to agricultural products. These acaricides for agricultural use have been developed for a long time, and recently new promising compounds have been discovered one after another.

[0003]

On the other hand, in recent years, due to changes in the living environment, house dust mites, dust mites, dust mites, etc. occur in the home, which not only causes discomfort, but also causes allergic asthma and skin rash. Is occurring. Organophosphorus agents such as Sumithion and Diazinon were known to be effective against mites that occur indoors, but there are obstacles to their practical use due to safety and resistance problems to humans and animals, and proper disinfection The establishment of a method has been earnestly desired.

[0004]

SUMMARY OF THE INVENTION In view of the above situation, the inventors of the present invention have conducted diligent research for the purpose of developing an acaricide that can be safely used indoors, and as a result, the pyrethroid system represented by the formula (I). Compound phenothrin alone, or isobornyl thiocyanoacetate (hereinafter referred to as IBTA),
Octachlorodipropyl ether (hereinafter referred to as S-421), piperonyl butoxide, N-2 (-ethylhexyl) -bicyclo [2,2,1] hept-5-ene-2,3-
Dicarboximide (hereinafter referred to as cinepyrine 222), N- (2-ethylhexyl) -1-isopropyl-
4-methylbicyclo [2,2,2] oct-5-ene-2,
A synergist for pyrethroid such as 3-dicarboximide (hereinafter referred to as cinepyrine 500), 2-butoxy-2′-thiocyanodiethyl ether (hereinafter referred to as Resen 384), and N, N-diethyl-m-toluamide. (Hereinafter referred to as diet), a composition containing one or two pest repellents such as benzylbenzoate,
The present invention has been completed by finding that it shows a very high acaricidal effect against dust mites and dust mites.

The present invention provides the formula (I) as an active ingredient:

Embedded image Or a compound of formula (I) and octachlorodipropyl ether, N- (2
-Ethylhexyl) -1-isopropyl-4-methylbicyclo [2,2,2] oct-5-ene-2,3-dicarboximide, N- (2-ethylhexyl) -bicyclo [2,2,1] hepta From the group consisting of -5-ene-2,3-dicarboximide, piperonyl butoxide, isobornyl thiocyanoacetate, 2-butoxy-2'-thiocyanoethyl ether, N, N-diethyl-m-toluamide and benzylbenzoate. 1 or 2 selected
PROBLEM TO BE SOLVED: To provide an aerosol agent for controlling indoor mites for carpet treatment, which comprises various compounds.

[0006]

BEST MODE FOR CARRYING OUT THE INVENTION By the way, the pyrethroid of the formula (I) has a high insecticidal activity and a broad insecticidal spectrum and is widely used as a highly safe insecticide for household and agricultural purposes. The acaricidal activity against citrus red mite and spider mites is extremely weak, and it has been conventionally difficult to apply them to mites in general. However, the present inventors consider that there are some ecological differences between mites attached to plants such as citrus mites, mitid mites and mites that occur indoors such as mites, dust mites, and for various compounds, for the latter mites As a result of examining the effect, surprisingly, the pyrethroid of the formula (I) has a particularly high acaricidal effect specifically on mites growing indoors, and in particular, has an activity surpassing Sumithion and diazinon against dust mites. It has been discovered that some new pyrethroids, which have recently been shown to have excellent spidericidal activity, are not always effective against mites growing indoors. Further, the compound of the formula (I) in which a cyano group is introduced at the benzyl position of the alcohol part is generally superior in insecticidal activity and acaricidal activity as compared with the original compound. On the contrary, it was revealed that the activity was decreased. These findings are completely unexpected from conventional findings, and considering that the pyrethroid of formula (I) is widely used as a safe insecticide for humans and animals, it can be used indoors. It is extremely useful for the development of acaricide. In addition, although two asymmetric carbons are present in the acid part of the compound of the formula (I) and four optical isomers are possible, each of them or any mixture thereof is of course included in the present invention.

IBTA, S-421, piperonyl butoxide, cinepyrine 222, cinepyrine 50
0, a pyrethroid synergist such as Reisen 384, and pest repellents such as diet and benzyl benzoate were also found to have some acaricidal effect. Furthermore, the pyrethroid of the formula (I) was supplemented with the above synergist and It was confirmed that the composition containing one or two pest repellents exhibits extremely high acaricidal effect which is additive or higher.

Although there are many unclear points as to why the pyrethroid of the formula (I) has a high specific control effect against the mites and dust mites that occur indoors, this type of mite belongs to the astigmatid species, while the plant It is considered that the morphological difference that the spider mites that attach to the mosquito are pre-Amphitates are related in part.

Synergists for pyrethroids have no insecticidal activity themselves, and when used together with pyrethroids, they are known to suppress the metabolic decomposition of pyrethroids in insect bodies and improve their insecticidal activity. It shows some acaricidal activity against the mites that develop, suggesting a difference in mechanism of action between insects and mites.

Further, the fact that the mixed composition of the pyrethroid of the formula (I) and the synergist for the pyrethroid shows a high synergistic effect,
The latter is very cheap and has high practical value.

[0011] Although date and benzyl benzoate are compounds that have been widely put to practical use as repellents for mosquitoes, flies, etc., it is interesting that they have an acaricidal effect, and the composition of the present invention containing them is suitable for the treatment of unpleasant pests. It can be used as a multipurpose composition including repellent and control of mites.

Although the above-mentioned active ingredients can be applied as they are to the acaricide of the present invention, it is usually preferable to use various carriers (including liquids) depending on the purpose of use, by using an appropriate carrier or other compounding agent. The term, means a liquid preparation having a water-soluble form, an emulsified form, or a suspension form, an emulsion, a wettable powder, an oil formulation,
It is used as a flowable agent, water solvent, etc.) and an aerosol agent. Examples of the liquid carrier include water, alcohols (methyl alcohol, ethyl alcohol, ethylene glycol etc.), ketones (acetone, methyl ethyl ketone, cyclohexanone etc.), ethers (ethyl ether, dioxane, cellosolves etc.), aliphatic Hydrocarbons (gasoline, kerosene, kerosene, etc.), aromatic hydrocarbons (benzene, toluene, xylene, methylnaphthalene, etc.), halogenated hydrocarbons (dichloromethane, trichlorobenzene, etc.), esters, acid amides, Solvents such as nitrites are suitable, and one or a mixture of two or more thereof is used.

Examples of solid carriers include clays (kaolin, bentonite, etc.), talcs, silicas,
Alumina powder, activated carbon, vegetable powder, etc. are suitable,
And these 1 type or a mixture of 2 or more types is used. Suitable compounding agents include emulsifiers, dispersants, spreading agents, penetrants, surfactants, stabilizers, etc.
One kind or a mixture of two or more kinds is used.

Alternatively, other acaricides, antioxidants, insecticides, which are not likely to inhibit the activity of the active ingredient of the present invention,
You may mix | blend a bactericide, a fungicide, a flavoring agent, and a coloring agent.

The amount of the active ingredient in the acaricide of the present invention and the amount thereof used are appropriately determined according to the dosage form, application target, application method, application site and the like. For example, to control mites that live in tatami mats such as mites, 0.1 mg or more per 1 tatami, preferably 1 mg
~ 2g of the pyrethroid compound of formula (I) is used. The tatami mats are infested with pests such as beetles and wasps, and the composition of the present invention can also control these pests at the same time.

[0016]

The present invention will be described in more detail with reference to the following examples, but the present invention is not limited to the following examples as long as the gist thereof is not exceeded.

Test Example 1 10 g of the powdered feed treated with the test compound and 10 g of the powdered feed containing about 2500 helminth mites were mixed to obtain a test powdered feed having a predetermined concentration. 5 g of each of the powdered feeds was placed in a petri dish having a diameter of 6 cm and placed under the conditions of a temperature of 25 ° C. and a humidity of 75%. After 1 week and 2 weeks, the number of living mites in 0.2 g of the feed was examined by the saturated saline floating method, and the reproductive inhibition rate was calculated according to the following formula. The test was repeated 3 times for each concentration.

[0018]

[Equation 1]

The symbols in the test compounds and pyrethroids
(a), (b), (c) and (d) have the following meanings. (a); Acid part dl-cis / trans form (b); Acid part d-cis / trans form (c); Acid part dl-cis form (d); Acid part d-trans form

[0020]

[Table 1]

[0021]

[Chemical 4]

From the above results, the composition of the present invention, that is, the compound of formula (I) or a composition obtained by adding one or two of a synergist for pyrethroid and a pest repellent (test compound examples 1 to 5) ) Showed an excellent acaricidal effect. On the other hand, the activity of the other pyrethroid compounds (control compounds (A), (B), (C)) and the synergist for pyrethroid or the pest repellent alone is very low, and the usefulness of the composition of the present invention was confirmed. It was

EXAMPLE 1 2.0 g of d-phenothrin and 5.0 g of IBTA were dissolved in refined kerosene, filled into an aerosol container and attached with a valve portion, and then a propellant was filled under pressure through the valve portion to obtain an aerosol. It was In a room of 6 tatami mats, in which the mite mite was propagated, the above-mentioned prepared aerosol was infused internally into about 1/4 tatami mat,
When the population density of mites was examined one week later, it was reduced to 5% or more. Similarly, when the aerosol prepared by using ethanol instead of refined kerosene was treated on the carpet in which the reproduction of Dermatophagoides farinae was observed, the same high exterminating effect was obtained.

Example 2 5 parts of d-phenothrin 5 parts of benzyl benzoate, 15 parts of Solbol SM-100 (trade name of Toho Kagaku),
75 parts of purified water was added to obtain an aqueous emulsion. This emulsion was diluted 500 times with water, treated with 100 g per m ^{2 of} base cloth, and dried to release about 300 Knotweed mites on the carpet. Two days later, the number of surviving Dermatophagoides farinae was examined and found to be 5 It was below.

Example 3 10 parts of dl-cis-phenothrin, 20 parts of IBTA, 35 parts of diatomaceous earth, 30 parts of clay, 3 parts of lauryl sulfonate,
A wettable powder was obtained by pulverizing and mixing 2 parts of carboxymethyl cellulose. This wettable powder was diluted 1000 times with water and treated on the surface of a carpet at 100 g / m ² . After drying
This carpet was used, but no infestation of Dermatophagoides farinae was observed, and there was no problem such as an offensive odor.

[0026]

INDUSTRIAL APPLICABILITY The present invention provides an aerosol agent excellent in controlling indoor mites.

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Claims (1)

[Claims] 1. Formula (I) as an active ingredient: Or a compound of formula (I) and octachlorodipropyl ether, N- (2
-Ethylhexyl) -1-isopropyl-4-methylbicyclo [2,2,2] oct-5-ene-2,3-dicarboximide, N- (2-ethylhexyl) -bicyclo [2,2,1] hepta From the group consisting of -5-ene-2,3-dicarboximide, piperonyl butoxide, isobornyl thiocyanoacetate, 2-butoxy-2'-thiocyanoethyl ether, N, N-diethyl-m-toluamide and benzylbenzoate. 1 or 2 selected
An indoor mite control aerosol for carpet treatment, consisting of several compounds.