JPS60120809A - Shampoo for depilatory prevention, hair tonic and restoration - Google Patents
Shampoo for depilatory prevention, hair tonic and restorationInfo
- Publication number
- JPS60120809A JPS60120809A JP22763283A JP22763283A JPS60120809A JP S60120809 A JPS60120809 A JP S60120809A JP 22763283 A JP22763283 A JP 22763283A JP 22763283 A JP22763283 A JP 22763283A JP S60120809 A JPS60120809 A JP S60120809A
- Authority
- JP
- Japan
- Prior art keywords
- hair
- shampoo
- linoleic acid
- oil
- growth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Abstract
Description
【発明の詳細な説明】
本発明は、頭皮を傷めることのない、脱毛防止、養毛、
発毛促進用シャンプーに関するものである。従来から禿
げはその原因として、遺伝的要素、食事の傾向、頭蓋骨
の張り、脳の発育不良、男性ホルモンの過剰、頭皮が薄
い等の種々の説が挙げられてきた。しかし、これら各種
の原因がどのように作用して、禿げるに到るのかという
メカニズムについては、未だ十分解明されていなかった
為に禿げた頭に頭髪を蘇生させることは不可能に近かっ
たのである。[Detailed description of the invention] The present invention provides hair loss prevention, hair growth, and hair growth without damaging the scalp.
This invention relates to a shampoo for promoting hair growth. Various theories have been proposed for the causes of baldness, including genetic factors, dietary trends, skull tension, poor brain development, excess male hormones, and thin scalp. However, the mechanism of how these various causes interact and lead to baldness has not yet been fully elucidated, making it nearly impossible to restore hair to a bald head. .
又、従来の脱毛防止・養毛・発毛促進剤とじては、ヒノ
キチオール、メントール、トウガラシチンキ、等の水溶
液を、これを頭皮に塗布して、頭皮の血液循環を良好に
保ち、二次的に毛体部の血液循環の改善を図り、脱毛の
防止・養毛・育毛を図っているものが多かった。In addition, conventional hair loss prevention, hair growth, and hair growth promoters include aqueous solutions of hinokitiol, menthol, chili pepper tincture, etc., which are applied to the scalp to maintain good blood circulation in the scalp and have secondary effects. Many of them aimed to improve blood circulation in the hair body area, prevent hair loss, and promote hair growth.
これらはいずれも、植物油の中に含まれる成分を主とす
る養毛・育毛剤であり、従来からも植物油が、頭皮の血
液の循環を良好に保ち、毛体部の血液循環の改善を図り
、脱毛の防止・養毛・育毛を図ることは知られていたの
である。All of these are hair nourishing and hair growth agents that mainly contain ingredients contained in vegetable oils, and vegetable oils have traditionally been used to maintain good blood circulation in the scalp and improve blood circulation in the hair body. It was known to prevent hair loss, nourish hair, and promote hair growth.
本発明者は、これらのタイワンヒノキ浦や、ハツカ油や
、トウガラシ油よりも、大豆油・綿実油・サフラワー油
・ゴマ油の方がより頭皮の血液の循環を図り、毛体部の
血液循環の改善を図ることを発見し、その原因をつきと
め、より効果的な使用法を発明したものである。The present inventor has found that soybean oil, cottonseed oil, safflower oil, and sesame oil improve blood circulation in the scalp and improve blood circulation in the hair body more than these Taiwanese cypress oils, pepper oil, and chili oil. They discovered things that could be improved, identified their causes, and invented more effective ways to use them.
即ち、天然の植物油のうち、大豆油・綿実油・サフラワ
ー油・ゴマ油などの混合脂肪酸は、その中にリノール酸
３５〜５５％程度含有しており、高度に含有しているサ
フラワー油にしても７７〜７８％程度であることは知ら
れている。そして、これらの天然組成の植物Ｍ１が養毛
・育毛に効果的であることは、薄々感しられていたので
あるが、養毛・育毛において顕著な効き目を確実に示す
ことができなかったのである。That is, among natural vegetable oils, mixed fatty acids such as soybean oil, cottonseed oil, safflower oil, and sesame oil contain about 35 to 55% linoleic acid, and compared to safflower oil, which contains a high amount of linoleic acid. It is known that the ratio is about 77 to 78%. Although it was vaguely felt that these plants with natural composition, M1, were effective for hair nourishment and growth, it was not possible to reliably demonstrate any significant effect on hair nourishment and hair growth. be.
本発明者は、この点を更に研究して、改良を進めた結果
、天然組成物である植物油をそのまま頭皮に塗布するよ
りも、リノール酸をより高純度にし、シャンプーの基剤
として、純度８０％以上のものを酸のまま、又はその塩
やエステルとして含有させると、顕著な効果が表れるこ
とを見い出したものである。As a result of further research on this point and progressing with improvements, the present inventor has made linoleic acid of higher purity than applying natural vegetable oil to the scalp as it is, and has used it as a shampoo base with a purity of 80%. It has been discovered that significant effects can be obtained when % or more of the acid is contained as an acid or as its salt or ester.
リノール酸は、大豆油・サフラワー油・綿実油・ゴマ油
等に大量に含まれている不飽和脂肪酸であり、食用や、
化粧用等にも広く用いられている脂肪酸である。人体に
対して無害であることは良く知られており、本発明の脱
毛防止・養毛・育毛用のシャンプーに使用しても、人体
に何らの有害作用も及ばないことが、使用者に安心感を
与え、養毛・育毛治療を始める要因ともなるのである。Linoleic acid is an unsaturated fatty acid that is contained in large amounts in soybean oil, safflower oil, cottonseed oil, sesame oil, etc.
It is a fatty acid widely used in cosmetics and the like. It is well known that it is harmless to the human body, and users can rest assured that there will be no harmful effects on the human body even if it is used in the hair loss prevention, hair growth, and hair growth shampoo of the present invention. It gives a sense of beauty and is a factor in starting hair growth treatment.
リノール酸は、２個の２重結合を有する非共役型不飽和
脂肪酸であり、９・１２−オクタデカジエン酸である。Linoleic acid is a non-conjugated unsaturated fatty acid having two double bonds, and is 9,12-octadecadienoic acid.
リノール酸の幾何異性体としては、シス−シス型・シス
−トランス型・トランス−シス型・トランス−トランス
型等があるが、天然の大豆油・サフラワー油・綿実油・
ゴマ油に含まれるリノール酸はシス−シス型でありシス
９−シス１２−オクタデカジエン酸である。Geometric isomers of linoleic acid include cis-cis type, cis-trans type, trans-cis type, trans-trans type, etc., but natural soybean oil, safflower oil, cottonseed oil, etc.
Linoleic acid contained in sesame oil is cis-cis type and is cis9-cis12-octadecadienoic acid.
化学式は、ＣＨａ （ＣＩ１２ ）４ Ｃ）Ｉ ＝Ｃｌ
ＩＣｌＩ２ Ｃｌｌ＝Ｃ１ｌ （Ｃ１１２）７ ・Ｃ０
０ＩＩで示される。グリセリンとして、大豆油・サフラ
ワー油・綿実油・ゴマ油等の多くの植物油中に含まれて
いる。このように天然の状態に含まれる重合の組成は、
大豆油等で３５〜５５％であり、高含有率を誇るサフラ
ワー油でも７７〜７８％である。これらの天然組成物を
、口ｎ皮に塗布することによっても効果があるが、より
含有率を上げて、８０％以上とすることにより、又酸そ
のままか、あるいは、その塩やエステルとして天然の油
脂がトリグリセライドの高分子であるのに対し、低分子
で用いることにより、顕著な効果を示すものである。The chemical formula is CHa (CI12)4 C)I = Cl
IClI2 Cll=C1l (C112)7 ・C0
Indicated by 0II. Glycerin is found in many vegetable oils such as soybean oil, safflower oil, cottonseed oil, and sesame oil. Thus, the composition of polymerization contained in the natural state is
Soybean oil and the like have a content of 35 to 55%, and even safflower oil, which boasts a high content, has a content of 77 to 78%. It is effective to apply these natural compositions to the mouth and skin, but by increasing the content to 80% or more, it is also possible to use natural compositions as they are, or as their salts or esters. While fats and oils are triglyceride polymers, they exhibit remarkable effects when used in low molecular weight forms.
高純度のリノール酸を得る方法としては、大豆油・サフ
ラワー油・綿実油・ゴマ油などの混合脂肪酸くリノール
酸含有量３５〜７７％）から固体脂肪酸を除いた後、精
製を繰り返して得る方法や尿素アダクト法がある。Highly pure linoleic acid can be obtained by removing solid fatty acids from mixed fatty acids such as soybean oil, safflower oil, cottonseed oil, and sesame oil (with a linoleic acid content of 35 to 77%), and then repeatedly refining the mixture. There is a urea adduct method.
性状は、無色油状液体で、融点−１２°−Ｃ１沸点２３
０ ” Ｃ、水に不溶、有機剤中に可溶、空気中で酸化
され易く硬化しやすい性質を持っている。Properties: Colorless oily liquid, melting point -12° - C1 boiling point 23
0''C, insoluble in water, soluble in organic agents, easily oxidized and hardened in the air.
故に、空気中で酸化され硬化しないように、リノール酸
と、トリエタノールアミンを当モルづつ配合してこれに
適当な水分を持たせて、シャンプーとして用いれば、頭
皮より吸収されなかった余分なリノール酸が洗い流され
、不飽和脂肪酸の酸化、重合による弊害もなく効果が顕
著であった。Therefore, if you mix equimolar amounts of linoleic acid and triethanolamine and use it as a shampoo to prevent it from oxidizing and hardening in the air, it will remove the excess linole that was not absorbed from the scalp. The acid was washed away, and the effect was remarkable without any adverse effects caused by oxidation or polymerization of unsaturated fatty acids.
次に脱毛防止、養毛、発毛用として作成したシャンプー
′の実施例を示すと、
試料の作成はそれぞれの脂肪酸１００ｇと、］−リリッ
タノールアミン５２．３に、１ｌｆｉ製水２４９ｇを加
え、湯浴中で８０℃を保ちながら３０分間攪拌してでき
たものを試料とした。Next, we will show an example of a shampoo made for hair loss prevention, hair nourishment, and hair growth.The sample was prepared by adding 249 g of 1lfi water to 100 g of each fatty acid and 52.3 g of ]-lirittanolamine. The sample was prepared by stirring in a hot water bath for 30 minutes while maintaining the temperature at 80°C.
上記の試料に基づき、臨床テストを行った。Based on the above samples, clinical tests were conducted.
対象男性、各テストにつき３０〜５０歳の５名づつを対
象とし、１日に１度、５ｇの試料を用いてシャンプーを
行ない、この結果を下記表に示すが、全体を総合して判
定を下したものである。For each test, 5 men between the ages of 30 and 50 were shampooed once a day using a 5g sample.The results are shown in the table below, but the overall results were evaluated as a whole. This is what was given.
Ａ：目立った効果なし
ＡＡ；産毛の少ない発生と軽度の発育を認めるＡＡＡ：
産毛の発生と硬毛化、発育を認めるＡＡＡＡ ：発育良
好
ＡＡＡＡＡ ：全体に密生し、顕著な効果を認める上記
結果から、本発明の理論の正しいごとが確認された。A: AA: No noticeable effect; AAA: Few occurrences of downy hair and mild growth observed:
AAAA in which the occurrence of downy hair, hardening, and growth are observed: Good growth AAAA: Dense growth throughout the hair, and a remarkable effect is observed From the above results, it was confirmed that the theory of the present invention is correct.
以上述べた如く、本発明は従来から、植物油が養毛・育
毛に効果的であるとされていたことの原因が、リノール
酸の毛球部の血液循環の改善作用や皮脂線の脂肪酸組成
の正常化にあることを突き止め、従来天然の組成物であ
り、５０％程度のリノール酸含有量の油（）・リグリセ
ライド）を頭部に塗布していた為に効果が顕著に表われ
なかった点を改善して、天然物の植物油を精製してリノ
ール酸の純度（脂肪酸組成）を８０％以」二に上げ、皮
膚吸収の良い低分子の状態（遊離脂ｎｔｊ酸のまま、又
は、低分子アルコールのエステル又はアルカリとの塩と
したもの）を塗布、又はシャンプーに含有せしめて用い
ることにより、既に短くなっている毛や、細毛化した毛
を発育させることはもとより、頭部の禿げた部分に、産
毛を発毛させ、更に、これを硬化、褐色、黒色化するこ
とに成功したものである。As described above, the present invention has demonstrated that the reason why vegetable oils have traditionally been considered effective for hair nourishment and growth is due to the effect of linoleic acid on improving blood circulation in the hair bulb and the fatty acid composition of sebaceous glands. It was found that the effect was not noticeable because the oil (glyceride), which is a natural composition and contains about 50% linoleic acid, was applied to the head. We improved this by refining natural vegetable oils to increase the purity (fatty acid composition) of linoleic acid to 80% or more, and converting it into a low-molecular state that is easily absorbed into the skin (as free fat ntj acid or with low levels). By applying esters of molecular alcohols or salts with alkalis) or adding them to shampoos, you can not only grow already short hair or thin hair, but also improve the appearance of bald spots on the head. We succeeded in growing downy hair in the area and also hardening, browning, and blackening the hair.
手続補正書（自発）
昭和５９年 ８月 ６日
特許庁長官 志 賀 学 殿
１、事件の表示
昭和５８年 特 許 願 第２２７６３２号２、発明の
名称
脱毛防止及び、養毛、発毛用シャンプー３、補正をする
者
事件との関係 出願人
住 所 八尾市安中町２丁目１番６４号氏 名 北 野
明 良
４、代理人
住 所 大阪市南区南船場１丁目１１番９号長堀八千代
ビル
明細書
別紙
６、補正の内容
（１）明細書第４頁第１１行目の「グリセリン」を「グ
リセライド」と補正致します。Procedural amendment (voluntary) August 6, 1980 Manabu Shiga, Commissioner of the Patent Office1, Indication of the case 1981 Patent Application No. 2276322, Name of the invention Shampoo for hair loss prevention, hair growth, and hair growth 3. Relationship with the case of the person making the amendment Applicant Address: 2-1-64 Annaka-cho, Yao City Name: Akira Kitano 4, Agent Address: Nagahori Yachiyo Building, 1-11-9 Minamisenba, Minami-ku, Osaka City Attachment 6 of the specification, details of amendment (1) "Glycerin" on page 4, line 11 of the specification will be corrected to "glyceride."
（２）明細書第８頁第６行目の「正常化にあること」を
「正常化そして、毛の発育を行なう毛母細胞の活性化に
あること」と補正致しまず。(2) The phrase "in normalization" on page 8, line 6 of the specification has been corrected to "in normalization and the activation of hair matrix cells that carry out hair growth."
手続補正書（自発）
昭和６０年 ２月２８日
昭和５８年 特 許 願 第２２７６３２号２、発明の
名称
脱毛防止及び、養毛、発毛用シャンプー３、補正をする
者
事件との関係 出願人
住 所 八尾市安中町２丁目１番６４号氏名 北野明良
４、代理人
住 所 大阪市南区南船場１丁目１１番９号５、補正の
対象
明細書
明 細 書
１０発明の名称
脱毛防止及び、養毛、発毛用シャンプー２、特許請求の
範囲
脂肪酸の組成として純度８０％以上のリノール酸を酸の
まま、或いは、アミン化合物として用いることを特徴と
する脱毛防止及び、養毛、発毛用シャンプー。Procedural amendment (spontaneous) February 28, 1985 Patent Application No. 227632 2, Name of the invention Hair loss prevention, hair growth, shampoo for hair growth 3, Relationship with the person making the amendment case Applicant Address: 2-1-64 Annaka-cho, Yao-shi Name: Akira Kitano 4, Agent address: 1-11-9-5 Minamisenba, Minami-ku, Osaka-shi Description 10 Name of the invention: Prevention of hair loss; Shampoo 2 for hair growth and hair growth, claims A hair loss prevention, hair growth and growth shampoo characterized by using linoleic acid with a purity of 80% or more as an acid or as an amine compound as a fatty acid composition. shampoo.
３、発明の詳細な説明
本発明は、頭皮を傷めることのない脱毛防止、養毛、発
毛促進用シャンプーに関するものである。3. Detailed Description of the Invention The present invention relates to a shampoo for preventing hair loss, nourishing hair, and promoting hair growth without damaging the scalp.
従来から禿げはその原因として、遺伝的要素、食事の傾
向、頭蓋骨の張り、脳の発育不良、男性ホルモンの過剰
、頭皮が薄い等の種々の説が挙げられてきた。しかし、
これら各種の原因がどのように作用して、禿げるに至る
のかというメカニズムについては未だ十分解明されてい
なかった為に禿げた頭に頭髪を蘇生させることは不可能
に近かったのである。Various theories have been proposed for the causes of baldness, including genetic factors, dietary trends, skull tension, poor brain development, excess male hormones, and thin scalp. but,
Because the mechanism of how these various causes interact and lead to baldness was not fully understood, it was nearly impossible to restore hair to a bald head.
また、従来の脱毛防止、養毛、発毛促進剤としては、ヒ
ノキチオール、メントール、トウカ゛ラシチンキ等の水
溶液や血圧降下剤として用もへられる血管拡張剤を頭皮
に塗布して、頭皮の血液（層頂を良好に保ち、二次的に
毛球部の血液循環の改善を図り、脱毛防止、養毛、発毛
を図ってｌＩ）るもの力（多かった。In addition, as conventional hair loss prevention, hair growth, and hair growth promoters, aqueous solutions such as hinokitiol, menthol, and tokalash tincture, as well as vasodilators that are also used as antihypertensive agents, are applied to the scalp, and blood (layers of blood in the scalp) are applied to the scalp. It maintains the top of the hair in good condition, secondarily improves blood circulation in the hair bulb, prevents hair loss, nourishes hair, and promotes hair growth.
本発明者は大豆油・綿実油・サフラワー油・ゴマ油が頭
皮の血液の循環を図り、毛球部の血液ｉ盾環の改善を図
ることからりノール酸の含有率（本屯度）に着目し、よ
り効果的な使用法を発明したものである。The present inventor focused on the content of nolic acid (base toughness) because soybean oil, cottonseed oil, safflower oil, and sesame oil promote blood circulation in the scalp and improve the blood shield ring in the hair bulb. He invented a more effective way to use it.
即ち、天然の植物油のうち、大豆油・綿実油・サフラワ
ー油・ゴマ油などの混合脂肪酸は、高度に含有している
サフラワー油にしても７７〜７８％程度であることは知
られている。そして、これらの天然組成の植物油が養毛
・養毛に効果的であることは、薄々感じられていたので
あるが、養毛・養毛において顕著な効き目を確実に示す
ことができなかったのである。That is, it is known that among natural vegetable oils, mixed fatty acids such as soybean oil, cottonseed oil, safflower oil, and sesame oil contain about 77 to 78% even if safflower oil contains a high content. Although it was vaguely felt that these natural vegetable oils were effective for hair growth and growth, it was not possible to reliably demonstrate any significant effect on hair health and growth. be.
本発明者は、この点を更に研究して、リノール酸の含有
率に着目し、改良を進めた結果、天然組成物である植物
油をそのまま頭皮に塗布するよりも、リノール酸の含有
率を高め、シャンプーの基剤として、リノール酸の純度
が８０％以上のものを酸のまま、或いはアミン化合物と
して含有させると、顕著な効果が表れることを見い出し
たものである。The present inventor further researched this point, focused on the content of linoleic acid, and made improvements. As a result, the content of linoleic acid was higher than that of applying natural vegetable oil to the scalp as it is. It has been discovered that when linoleic acid with a purity of 80% or more is contained as an acid or as an amine compound as a shampoo base, remarkable effects are exhibited.
リノール酸は、大豆油・サフラワー浦・綿実油・ゴマ油
頭に大量に含まれている不飽和脂肪酸であり、必須脂肪
酸である。又、化粧用等にも広く用いられている脂肪酸
である。人体に対して無害であることは良く知られてお
り、本発明の脱毛防止、養毛、養毛用のシャンプーに使
用しても、人体に何らの有害作用も及ばないことが、使
用者に安心感を与え、養毛・養毛治療を始める要因とな
るものである。Linoleic acid is an unsaturated fatty acid that is found in large amounts in soybean oil, safflower oil, cottonseed oil, and sesame oil, and is an essential fatty acid. It is also a fatty acid widely used in cosmetics and the like. It is well known that it is harmless to the human body, and users can be assured that the hair loss prevention, hair growth, and hair growth shampoo of the present invention will not have any harmful effects on the human body. This provides a sense of security and is a factor in starting hair growth/hair restoration treatment.
リノール酸は、２個の２重結合を有する非共役型不飽和
脂肪酸であり、９・１２−オクタデカジエン酸である。Linoleic acid is a non-conjugated unsaturated fatty acid having two double bonds, and is 9,12-octadecadienoic acid.
リノール酸の幾何異性体としては、シスーシス型、シス
−トランス型、トランス−シス型、トランス−トランス
型等があるが、天然の大豆油・サフラワー油・綿実油・
ゴマ油に含まれるリノール酸はシス−シス型であり、シ
ス９−シス１２−オフデカジエン酸である。Geometric isomers of linoleic acid include cis-cis, cis-trans, trans-cis, trans-trans, etc., but natural soybean oil, safflower oil, cottonseed oil,
Linoleic acid contained in sesame oil is cis-cis type, and is cis9-cis12-ofdecadienoic acid.
化学式は、ＣＩＩ ａ （ＣＨ２）９ＣＩ ＝ＣＨＣＨ
ｚ Ｃｔｌ ＝ＣＨ（ＣＨ２）７・Ｃ００ＩＩで示され
る。グリセライドとして、大豆油・サフラワー油・綿実
油・ゴマ油等の多ぐの植物油中に含まれている。このよ
うに天然の状態に含まれる場合の組成は、大豆油等で３
５〜５５％であり、高含有率を誇るサフラワー油でも７
７〜７８％である。The chemical formula is CII a (CH2)9CI = CHCH
It is represented by z Ctl =CH(CH2)7·C00II. As a glyceride, it is contained in many vegetable oils such as soybean oil, safflower oil, cottonseed oil, and sesame oil. In this way, when contained in its natural state, the composition is soybean oil, etc.
Even safflower oil, which has a high content of 5 to 55%, has a 7%
It is 7-78%.
これらの天然組成物を、頭皮に塗布することによっても
効果があるが、より含有率を上げて、８０％以上とする
ことにより、又、酸そのままか、或いは、アミン化合物
として、天然の油脂がトリグリセライドの高分子である
のに対し、低分子で用いることにより、顕著な効果を示
すものである。It is effective to apply these natural compositions to the scalp, but by increasing the content to 80% or more, natural oils and fats can be used as acids or as amine compounds. Unlike triglyceride, which is a polymer, it shows remarkable effects when used as a low molecule.
高純度のリノール酸を得る方法としては、大豆油・サフ
ラワー油・綿実油・ゴマ油などの混合脂肪酸（リノール
酸含有率３５〜７７％）から冷却し、固体脂肪酸を除い
た後、精製を繰り返して得る方法や尿素アダクト法があ
る。To obtain high-purity linoleic acid, mixed fatty acids (linoleic acid content: 35-77%) such as soybean oil, safflower oil, cottonseed oil, and sesame oil are cooled, solid fatty acids are removed, and then refining is repeated. There are methods to obtain it and urea adduct method.
性状は、無色油状液体で、融点−１２℃、沸点２３０℃
、水に不溶、有機剤中に可溶、空気中で酸化され易く硬
化しやすい性質を持っている。Properties: Colorless oily liquid, melting point -12℃, boiling point 230℃
, insoluble in water, soluble in organic agents, easily oxidized and hardened in the air.
故に、酸化の進んでいないリノール酸と、トリエタノー
ルアミンを当モルづつ配合して、これに適当な水分を持
たせて、シャンプーとして用いれば、頭皮より吸収され
なかった余分なリノール酸が洗い流され、不飽和脂肪酸
の酸化、重合による弊害もなく効果が顕著であった。Therefore, if you mix equal moles of linoleic acid, which is not oxidized, and triethanolamine, add an appropriate amount of moisture, and use it as a shampoo, the excess linoleic acid that was not absorbed from the scalp will be washed away. The effect was remarkable, with no adverse effects caused by oxidation or polymerization of unsaturated fatty acids.
次に脱毛防止、養毛、発毛用として作成したシャンプー
の実施例を示すと、
試料の作成はそれぞれの脂肪酸１００ｇと、トリエタノ
ールアミン５２．３ｇに、精製水２４９ｇを加え、湯浴
中８０℃を保ちながら３０分間攪拌してできたものを試
料とした。Next, an example of a shampoo prepared for hair loss prevention, hair growth, and hair growth is shown. Samples were prepared by adding 249 g of purified water to 100 g of each fatty acid and 52.3 g of triethanolamine, and adding 249 g of purified water to 100 g of each fatty acid and 52.3 g of triethanolamine. The sample was prepared by stirring for 30 minutes while maintaining the temperature.
上記の試料に基づき、臨床テストを行った。Based on the above samples, clinical tests were conducted.
対象男性、各テストにつき３０〜５０歳の５名づつを対
象とし、１日に１度、５ｇの試料を用いてシャンプーを
行い、この結果を下記表に示すが、全体を総合して判定
を下したものである。For each test, 5 men between the ages of 30 and 50 were shampooed once a day using 5g of the sample.The results are shown in the table below, but the results were evaluated based on the overall results. This is what was given.
Ａ：目立った効果なし
ＡＡ：産毛の少ない発生と軽度の発毛を認めるＡＡＡ
：産毛の発生と硬毛化、発育を認めるＡＡＡＡ ：発育
良好
ＡＡＡＡＡ ：全体に密生し、顕著な効果を認める上記
の結果から、本発明の理論が正しいことが確認された。A: No noticeable effect AA: AAA with minimal occurrence of downy hair and mild hair growth
: Generation of downy hair, hardening, and growth are observed AAAA : Good growth AAAA : Dense hair grows all over, and a remarkable effect is observed From the above results, it was confirmed that the theory of the present invention is correct.
以上述べた如く、本発明は従来から、植物油が養毛・育
毛に効果的であるとされていたが、５０％程度のリノー
ル酸含有率の油（トリグリセライド）を頭部に塗布して
も効果が顕著に表れなかった点を改善して、天然物の植
物油を精製してリノール酸の純度（脂肪酸組成）を８０
％以上に上げ、皮膚吸収の良い低分子の状態（Ｍ離脂肪
酸のまま、又は、アミン化合物としたもの）を塗布、又
はシャンプーに含有せしめて用いることにより、既に短
くなっている毛や、細毛化した毛を発育させることはも
とより、頭部の禿た部分に、産毛を発毛させ、更に、こ
れを硬化、褐色、黒色化することに成功したものである
。As mentioned above, the present invention is based on the conventional wisdom that vegetable oil is effective for hair growth and growth, but applying oil with a linoleic acid content of about 50% (triglyceride) to the head is also effective. In order to improve the problem that linoleic acid was not noticeable, the purity of linoleic acid (fatty acid composition) was reduced to 80% by refining natural vegetable oil.
% or higher, and by applying a low-molecular state (M fatty acid as it is or as an amine compound) that is easily absorbed by the skin, or by adding it to the shampoo, it can be applied to hair that is already short or thin. In addition to growing curly hair, we have succeeded in growing downy hair on bald areas of the head, and also in hardening, browning, and blackening the hair.
又、シャンプーの成分として、リノール酸、或いは、そ
のアミン化合物が脂肪酸組成として影響されない物質（
水等）の添加については制約しないものである。即ち、
シャンプーに含まれるすべての脂肪酸を取り出した場合
、リノール酸純度が８０％以上と規定したものである。In addition, as a component of shampoo, linoleic acid or its amine compound is a substance that is not affected by the fatty acid composition (
There are no restrictions on the addition of water, etc.). That is,
When all the fatty acids contained in the shampoo are extracted, the purity of linoleic acid is defined as 80% or more.
Claims (1)
まま、あるいは、その塩又はエステルとして用いること
を特徴とする脱毛防止及び、養毛、発毛用シャンプー。A shampoo for hair loss prevention, hair nourishment, and hair growth, characterized in that linoleic acid with a purity of 80% or more is used as an acid or as a salt or ester thereof as a fatty acid composition.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22763283A JPS60120809A (en) | 1983-11-30 | 1983-11-30 | Shampoo for depilatory prevention, hair tonic and restoration |
| GB08419216A GB2150588A (en) | 1983-11-30 | 1984-07-27 | Shampoo for promoting growth of hair |
| DE19843430166 DE3430166A1 (en) | 1983-11-30 | 1984-08-16 | SHAMPOO FOR PREVENTING HAIR LOSS AND PROMOTING HAIR GROWTH |
| FR8414500A FR2555442A1 (en) | 1983-11-30 | 1984-09-21 | SHAMPOO TO PREVENT THE FALL OF HAIR AND PROMOTE HAIR GROWTH |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22763283A JPS60120809A (en) | 1983-11-30 | 1983-11-30 | Shampoo for depilatory prevention, hair tonic and restoration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS60120809A true JPS60120809A (en) | 1985-06-28 |
Family
ID=16863945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP22763283A Pending JPS60120809A (en) | 1983-11-30 | 1983-11-30 | Shampoo for depilatory prevention, hair tonic and restoration |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS60120809A (en) |
| DE (1) | DE3430166A1 (en) |
| FR (1) | FR2555442A1 (en) |
| GB (1) | GB2150588A (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0309086A1 (en) * | 1987-09-07 | 1989-03-29 | Efamol Holdings Plc | Treatment of male pattern baldness and of unwanted hair growth |
| US5116605A (en) * | 1989-03-09 | 1992-05-26 | Alt John P | Composition and skin treatment method therewith for mitigating acne and male-pattern baldness |
| DE4339580C2 (en) * | 1993-11-19 | 1994-11-24 | Steffen Schmelzer | Device for flow flying people in an air stream |
| WO1996019187A1 (en) * | 1994-12-22 | 1996-06-27 | Tovarischestvo S Ogranichennoi Otvetstvennostju 'firma Plus' | Agent for stimulating hair growth |
| TW200407172A (en) * | 2002-10-17 | 2004-05-16 | Unilever Nv | Scalp treatment |
| US8470833B2 (en) | 2009-12-15 | 2013-06-25 | Mcneil-Ppc, Inc. | Hair growth and/or regrowth compositions |
| DK3145490T3 (en) * | 2014-05-06 | 2018-06-25 | Fidia Farm Spa | LIPOSOMES CONTAINING DI-HOMO-GAMMA LINOLIC ACID (DGLA), FORMULATIONS CONTAINING THEM AND APPLICATION THEREOF |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5914154A (en) * | 1982-07-13 | 1984-01-25 | Sanyo Electric Co Ltd | Electrode forming method of scanning stylus |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA700516A (en) * | 1964-12-22 | Siegal Bernard | Emulsion compositions | |
| DE1136056B (en) * | 1958-05-16 | 1962-09-06 | Georg Dralle Fa | Hair care product with hair growth promoting effect |
| FR2097036A1 (en) * | 1970-07-29 | 1972-03-03 | Sopharga Lab | Lipids contg fatty acids - for treatment of atheroslerosis |
| FR2380775A1 (en) * | 1977-02-22 | 1978-09-15 | Sederma Sarl | "AFTER-DEPILATION" COMPOSITION PROMOTING A PROGRESSIVE SLOWING OF HAIR REGROWTH |
| LU78168A1 (en) * | 1977-09-22 | 1979-05-25 | F Genieyz | SKIN TREATMENT COMPOSITION AND PREPARATION METHOD |
| FR2474310A1 (en) * | 1980-01-25 | 1981-07-31 | Oreal | STABLE SOLUTION WITH OXIDATION OF VITAMIN F AND JOJOBA OIL AND COSMETIC COMPOSITIONS CONTAINING THE SAME |
| DE3124701A1 (en) * | 1981-06-24 | 1983-01-13 | Boehringer Ingelheim KG, 6507 Ingelheim | NEW L-SUBSTITUTED IMIDAZO (1,2-A) IMIDAZOLES, THEIR ACID ADDITION SALTS, THE MEDICINAL PRODUCTS CONTAINING THEM AND METHOD FOR THE PRODUCTION THEREOF |
| DE3143624C2 (en) * | 1981-11-03 | 1983-11-24 | Bernhard 2800 Bremen Woitkowski | Cosmetic agent for strengthening and promoting hair growth and process for its production |
| EP0116439A3 (en) * | 1983-02-02 | 1986-01-29 | Suntory Limited | Fatty acid containing hair tonic composition |
-
1983
- 1983-11-30 JP JP22763283A patent/JPS60120809A/en active Pending
-
1984
- 1984-07-27 GB GB08419216A patent/GB2150588A/en not_active Withdrawn
- 1984-08-16 DE DE19843430166 patent/DE3430166A1/en not_active Ceased
- 1984-09-21 FR FR8414500A patent/FR2555442A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5914154A (en) * | 1982-07-13 | 1984-01-25 | Sanyo Electric Co Ltd | Electrode forming method of scanning stylus |
Also Published As
| Publication number | Publication date |
|---|---|
| GB8419216D0 (en) | 1984-08-30 |
| FR2555442A1 (en) | 1985-05-31 |
| DE3430166A1 (en) | 1985-06-05 |
| GB2150588A (en) | 1985-07-03 |
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