JPS59210010A - Hair lotion - Google Patents
Hair lotionInfo
- Publication number
- JPS59210010A JPS59210010A JP58083529A JP8352983A JPS59210010A JP S59210010 A JPS59210010 A JP S59210010A JP 58083529 A JP58083529 A JP 58083529A JP 8352983 A JP8352983 A JP 8352983A JP S59210010 A JPS59210010 A JP S59210010A
- Authority
- JP
- Japan
- Prior art keywords
- hinokitol
- hair lotion
- beta
- scalp
- glycyrrhetinic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000006210 lotion Substances 0.000 title claims abstract description 15
- FUWUEFKEXZQKKA-UHFFFAOYSA-N beta-thujaplicin Chemical compound CC(C)C=1C=CC=C(O)C(=O)C=1 FUWUEFKEXZQKKA-UHFFFAOYSA-N 0.000 claims abstract description 25
- TUFYVOCKVJOUIR-UHFFFAOYSA-N alpha-Thujaplicin Natural products CC(C)C=1C=CC=CC(=O)C=1O TUFYVOCKVJOUIR-UHFFFAOYSA-N 0.000 claims abstract description 15
- MPDGHEJMBKOTSU-YKLVYJNSSA-N 18beta-glycyrrhetic acid Chemical compound C([C@H]1C2=CC(=O)[C@H]34)[C@@](C)(C(O)=O)CC[C@]1(C)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@H](O)C1(C)C MPDGHEJMBKOTSU-YKLVYJNSSA-N 0.000 claims abstract description 8
- 229930007845 β-thujaplicin Natural products 0.000 claims description 10
- 210000004761 scalp Anatomy 0.000 abstract description 7
- 208000001840 Dandruff Diseases 0.000 abstract description 5
- 208000003251 Pruritus Diseases 0.000 abstract description 5
- 230000000622 irritating effect Effects 0.000 abstract description 5
- 238000002156 mixing Methods 0.000 abstract description 3
- 239000002253 acid Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 9
- 235000019441 ethanol Nutrition 0.000 description 7
- -1 polyoxyethylene Polymers 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 3
- 239000003205 fragrance Substances 0.000 description 3
- 230000007803 itching Effects 0.000 description 3
- 239000008213 purified water Substances 0.000 description 3
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000002736 nonionic surfactant Substances 0.000 description 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 2
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 1
- ISAOCJYIOMOJEB-CYBMUJFWSA-N (R)-benzoin Chemical compound O=C([C@H](O)C=1C=CC=CC=1)C1=CC=CC=C1 ISAOCJYIOMOJEB-CYBMUJFWSA-N 0.000 description 1
- HVYWMOMLDIMFJA-UHFFFAOYSA-N 3-cholesterol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 HVYWMOMLDIMFJA-UHFFFAOYSA-N 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- 240000008574 Capsicum frutescens Species 0.000 description 1
- XUYPXLNMDZIRQH-LURJTMIESA-N N-acetyl-L-methionine Chemical compound CSCC[C@@H](C(O)=O)NC(C)=O XUYPXLNMDZIRQH-LURJTMIESA-N 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000005215 alkyl ethers Chemical class 0.000 description 1
- 239000001390 capsicum minimum Substances 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229940014662 pantothenate Drugs 0.000 description 1
- 239000011713 pantothenic acid Substances 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 description 1
- 229960001153 serine Drugs 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
- 239000011726 vitamin B6 Substances 0.000 description 1
- 235000019158 vitamin B6 Nutrition 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
Abstract
Description
【発明の詳細な説明】
本発明はヘア・ロー７ョンに関し、更に詳しくはヒノキ
チオールを配合したふけとり、かゆみ止め用のヘア・ロ
ーションである。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a hair lotion, and more particularly to a hair lotion containing hinokitiol for removing dandruff and preventing itching.
従来、ふけの発生や頭皮のかゆみをとめるだめのヘア・
ローションにヒノキチオールを配合しているが、その配
合濃度はｏ、 ｏ ｉ〜００５駕％が限度であり、この
配合範囲を超えるヘア・ローションは頭皮に対する刺激
作用が強くなりすぎて使用に適さなくなるという欠点が
あった。Traditionally, hair products have been used to stop dandruff and scalp itching.
The lotion contains hinokitiol, but its concentration is limited to 0.005%, and it is said that hair lotions that exceed this range will have too strong an irritant effect on the scalp and be unsuitable for use. There were drawbacks.
本発明者は、この欠点を解消すべく研究の結果、前記配
合範囲を超えるヒノキチオールを配合しても、その１〜
２倍量のβ−グリチルレチン酸を配合することにより、
ヒノキチオールの好ましい作用を維持しながら、好捷し
くない刺激作用は抑制することに成功し、本発明を完成
した。As a result of research to eliminate this drawback, the present inventor found that even if hinokitiol exceeding the above blending range is blended,
By incorporating double the amount of β-glycyrrhetinic acid,
The present invention has been completed by successfully suppressing the unfavorable stimulating effects of hinokitiol while maintaining its favorable effects.
本発明はヒノキチオールおよびβ−グリチルレチン酸を
１１〜２の重量比で配合することを特徴とするヘア・ロ
ーションである。The present invention is a hair lotion characterized by containing hinokitiol and β-glycyrrhetinic acid in a weight ratio of 11 to 2.
本発明において、ヒノキチオールの配合沿は用途に応じ
て００５Ｗ／Ｖ％を超える適当な量でよいが、望ましく
は０１〜０２′Ｗ／Ｖ％の範囲である１、必要に応じて
薬効成分（たとえば、Ｌ−セリン、Ｎ−アセチル−Ｌ−
メチオニン、コレステリン、安息香チンキ、トウガラシ
チンキ、レノ゛ル／ン、セファランチン、パントテン酸
塩、ビタミンＢ６．銅−ヒラキチンなど）、非イオン界
面活性剤（たとえばホ１ノオキシエチレンアルキルエー
テル、アルキルアリルエーテル、ポリオキシエチレン脂
肪酸エステルなど）、炭素数１〜乙の１価まだは２価の
アルコール（７’ｃトｉｆｆ、エチルアルコール、グロ
ピルアルコール、エチｔ／ンクリコール、クリセリンな
ど）、香料２着色剤、精製水などを配合することができ
る。In the present invention, the formulation of hinokitiol may be in an appropriate amount exceeding 005 W/V% depending on the use, but preferably in the range of 01 to 02' W/V%. , L-serine, N-acetyl-L-
Methionine, cholesterin, benzoin tincture, capsicum tincture, lenol/one, cephalanthine, pantothenate, vitamin B6. copper-hyrachitin, etc.), nonionic surfactants (e.g., polyoxyethylene alkyl ether, alkyl allyl ether, polyoxyethylene fatty acid ester, etc.), monohydric or dihydric alcohols having 1 to 2 carbon atoms (7' c-tiff, ethyl alcohol, glopylic alcohol, ethyl alcohol, chrycerin, etc.), fragrances, coloring agents, purified water, etc. can be blended.
本発明のヘア・ロー７ョンは、たとえば次の方法により
調製するととができる。The hair lotion of the present invention can be prepared, for example, by the following method.
すなわち、ヒノキチオール、β−グリチルレチン酸およ
びその他必要とする薬効成分、香料９着色剤などをアル
コールに溶解する。、非イオン界面活性剤を精製水に溶
解し、これに前記アルコール溶液を溶解してヘア・ロー
ションを得ることができる。That is, hinokitiol, β-glycyrrhetinic acid, other necessary medicinal ingredients, fragrance 9, coloring agent, etc. are dissolved in alcohol. A hair lotion can be obtained by dissolving a nonionic surfactant in purified water and dissolving the alcohol solution therein.
本発明のヘア・ローションは、ふけの発生や頭皮のかゆ
みを強力にとめて、しかも頭皮への好ましくない刺激作
用が著しく小さい、すぐれたヘア口−ンヨンである。The hair lotion of the present invention is an excellent hair lotion that strongly suppresses the occurrence of dandruff and itching of the scalp, and has significantly less undesirable irritating effect on the scalp.
以下、試験例と実施例をあげて、本発明を具体的に説明
する。The present invention will be specifically explained below with reference to Test Examples and Examples.
試験例
ヒノキチオールとβ−グリチルレチン酸とを各種割合で
含有する被験ヘア・ローションを後記実施例に準じて調
製した。Test Examples Test hair lotions containing hinokitiol and β-glycyrrhetinic acid in various proportions were prepared according to the examples below.
正常な成人男女２０人を１群とし、各被験ヘア・ローシ
ョンをそれぞれ別個の群に適用（ｔ１ｍｅ／人／回１日
６回）し、頭皮に刺激を感じだ人の数を調べた。Each test hair lotion was applied to a separate group of 20 normal adult men and women (t1me/person/time, 6 times a day), and the number of people who felt scalp irritation was determined.
その結果を第１表に示す。The results are shown in Table 1.
実施例 １
ヒノキチオール０１７．β−グリチルレチン酸０．１ｉ
ｉ’、香料０９２をエチルアルコール５７７に溶解した
。Example 1 Hinokitiol 017. β-Glycyrrhetinic acid 0.1i
i', fragrance 092 was dissolved in ethyl alcohol 577.
ポリオキシエチレンヒマシ油５７をＭ製水ａａｍ７！に
溶解し、これに前記アルコール溶液を溶解した後、精製
水を加えて全量を１００１ｎｅとし、ヘア・ローンヨン
を得た。M water aam7 polyoxyethylene castor oil 57! After dissolving the alcohol solution therein, purified water was added to make the total amount 1001 ne to obtain hair lawn yong.
実施例 ２
実施例１に準じて、下記処方のヘア・ローションを調製
した。Example 2 According to Example 1, a hair lotion having the following formulation was prepared.
Claims (1)
１〜２の重量比で配合することを特徴とするヘア・ロー
ション。1) hinokitiol and β-glycyrrhetinic acid in 1:
A hair lotion characterized by being blended at a weight ratio of 1 to 2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58083529A JPS59210010A (en) | 1983-05-13 | 1983-05-13 | Hair lotion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58083529A JPS59210010A (en) | 1983-05-13 | 1983-05-13 | Hair lotion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS59210010A true JPS59210010A (en) | 1984-11-28 |
Family
ID=13805013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58083529A Pending JPS59210010A (en) | 1983-05-13 | 1983-05-13 | Hair lotion |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS59210010A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6322506A (en) * | 1986-07-14 | 1988-01-30 | Shiseido Co Ltd | External preparation for skin |
| JPS6322507A (en) * | 1986-07-14 | 1988-01-30 | Shiseido Co Ltd | External preparation for skin |
| JPH02243607A (en) * | 1989-03-16 | 1990-09-27 | Arusoa Sogo Kenkyusho:Kk | Antiseptic agent for cosmetic and cosmetic containing same |
| KR100517553B1 (en) * | 1998-08-25 | 2006-02-17 | 주식회사 태평양 | Hair-care codmetic composition having dandruff formation-suppressing effect |
-
1983
- 1983-05-13 JP JP58083529A patent/JPS59210010A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6322506A (en) * | 1986-07-14 | 1988-01-30 | Shiseido Co Ltd | External preparation for skin |
| JPS6322507A (en) * | 1986-07-14 | 1988-01-30 | Shiseido Co Ltd | External preparation for skin |
| JPH02243607A (en) * | 1989-03-16 | 1990-09-27 | Arusoa Sogo Kenkyusho:Kk | Antiseptic agent for cosmetic and cosmetic containing same |
| KR100517553B1 (en) * | 1998-08-25 | 2006-02-17 | 주식회사 태평양 | Hair-care codmetic composition having dandruff formation-suppressing effect |
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