JPH06128587A - Detergent composition - Google Patents

Abstract

PURPOSE:To obtain a detergent compsn. which irritates the skin very little. CONSTITUTION:A detergent compsn. is prepd. by compounding at least one compd. selected from an N-acyl amino acid and its salt with at least one compd. selected from at least either glycyrrhizic acid and its salt or an extraxt of a horse chestnut. The compsn. may further contain an oil component, a nonionic surfactant, an amphoteric surfactant, a higher alcohol, a humectant, a thickener, a conditioning agent, a sequestering agent, a pH regulator, an ultraviolet absorber, a bacteriocide, an antiseptic, a pigment, a perfume, etc. The compsn. can be used, e.g. as a shampoo, a body shampoo, a hand cleanser, a face cleanser, a kitchen cleanser, a detergent for cloths, a pet shampoo, a carpet shampoo, a house shampoo, etc.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cleansing composition having extremely low skin irritation.

[0002]

2. Description of the Related Art Conventionally, anionic surfactants having a sulfonic acid group or a sulfuric acid group, such as olefin sulfonates, alkyl sulfates, alkyl ether sulfates, etc., have been used as detergents because of their good foamability and detergency Has been used.

[0003]

However, continuous use of detergents containing these surfactants as the main ingredient may cause hand roughening, etc., so that people involved in dishwashing at home, dishwashing as work, and hair washing etc. may get rough hands. There has been a demand for a cleaning agent that does not cause It is considered that such rough hands are caused by the strong protein denaturing power of the above-mentioned surfactant and primary skin irritation. For this reason, detergents using a surfactant having a lower protein denaturing power or a component having a low primary skin irritation have been proposed, but none have been sufficiently satisfied.

[0004]

[Means and Actions for Solving the Problems] The inventors have conducted earnest research for the purpose of solving the above problems.
With N-acyl amino acid or its salt as the main component,
When at least one of glycyrrhizic acid, a salt of glycyrrhizic acid, and horse chestnut extract is added to this, the protein denaturing power and primary skin irritation are low, it does not cause rough hands and the like, and is excellent in cleanability and foamability. The inventors have found that a cleaning agent can be obtained, and completed the present invention.

That is, the cleaning composition of the present invention comprises one or more components selected from the following (a) group and one or more components selected from at least one of the following (b) group and (c) group. And a component of. (A) N-acyl amino acids and salts thereof.

(B) Glycyrrhizic acid and salts thereof. (C) Horse chestnut extract. Hereinafter, the present invention will be described in more detail. The N-acyl amino acid and its salt as the component (a) used in the present invention are represented by the following general formula (1).

[0007]

[Chemical 1]

However, in the formula (1), R ₁ has 9 to ₁ carbon atoms.
8, a straight-chain alkyl group or a branched alkylene group, R ₂
Is H or an alkyl group having 1 to 4 carbon atoms, R ₃ is 1 carbon atom
The linear or branched alkylene group represented by the formula (1) to (2) or the group represented by the general formula shown in the following formula (2) is usually used.

[0009]

[Chemical 2]

Examples of N-acyl amino acids and salts thereof of this group (a) include N-acyl-L-glutamic acids, N-acyl sarcosines and N-acyl-N-methyl-β-alanines. . To further exemplify these, as N-acyl-L-glutamic acids,
N-lauroyl-L-glutamic acid, N-stearoyl-L-glutamic acid, N-palmitoyl-L-glutamic acid, N-myristoyl-L-glutamic acid, N-oleoyl-L-glutamic acid, N-coconut fatty acid acyl-
L-glutamic acid, N-hardened beef tallow fatty acid acyl-L-glutamic acid, N-coconut oil fatty acid / hardened beef tallow fatty acid acyl-L-glutamic acid, N-acyl (12-18) -L-
Examples thereof include glutamic acid and sodium, potassium, monoethanolamine, diethanolamine, triethanolamine salts thereof and the like.

Further, as N-acyl sarcosines,
Oleoyl sarcosine, lauroyl sarcosine, myristoyl sarcosine, palmitoyl sarcosine, stearoyl sarcosine, beheroyl sarcosine, coconut oil fatty acid sarcosine, coconut oil fatty acid methyl taurine, N-myristoyl methyl taurine, N-palmitoyl methyl taurine, N-stearoyl methyl taurine, N-beheroylmethyl taurine and their sodium, potassium,
Examples thereof include ammonium, monoethanolamine, diethanolamine and triethanolamine salts.

Further, as N-acyl-N-methyl-β-alanines, N-myristoyl-N-methyl-β is available.
-Alanine, N-lauroyl-N-methyl-β-alanine, N-coconut oil fatty acid-N-methyl-β-alanine and their sodium, potassium, monoethanolamine, diethanolamine, triethanolamine salts and the like.

Among these, N- because of the fineness of bubbles.
Acyl-L-glutamic acids are particularly preferred. Further, the blending amount thereof is preferably 3% by weight or more from the viewpoint of foaming. Glycyrrhizic acid and a salt thereof as the (b) group component in the present invention are the medicinal components of licorice (liquorice) known as an important herbal medicine of Kampo, and have reported anti-inflammatory action, anti-allergic action, detoxification action, and wound healing action. Has been done. Examples of the salt include trisodium, dipotassium and ammonium salts. Among these, it is preferable to use dipotassium glycyrrhizinate because of its solubility in water. (B)
If the compounding amount of the group component is less than 0.01% by weight, the effect starts to decrease, and if it exceeds 1.0% by weight, the solubility in the solution containing the N-acylamino acid becomes low. Therefore, the blending amount of the component (b) is preferably 0.01% by weight to 1.0% by weight.

The horse chestnut extract, which is a component of group (c), is an extract from horse chestnut and is a substance for which escin contained therein has an anti-inflammatory action and an anti-edema action. (C) Group component content is 0.001% by weight
If it is less than 1.0%, the effect tends to be low, and if it exceeds 1.0% by weight, the solubility in a solution containing an N-acylamino acid becomes low. Therefore, the blending amount of the group (c) component is preferably 0.001% by weight to 1.0% by weight as a solid content.

A component selected from the group (a),
Even if only one of the components of the (b) group or the (c) group is blended, a detergent composition which does not cause rough hands and has excellent detergency and foamability can be obtained. It is even better to incorporate ingredients selected from both groups.

The detergent composition of the present invention may contain, as an optional component, components generally used in detergents. For example, oils, nonionic surfactants, amphoteric surfactants, higher alcohols, humectants, thickeners, conditioning agents, sequestering agents, pH adjusters, UV absorbers, bactericides, preservatives, dyes, fragrances, etc. .

The detergent composition of the present invention can be used, for example, as a shampoo, a body shampoo, a hand-washing detergent, a facial cleanser, a kitchen detergent, a laundry detergent, a pet shampoo, a carpet shampoo, a residential shampoo and the like. .

[0018]

EXAMPLES Examples 1 to 5 prepared as shampoos with the compounding ratios shown in Table 1 below, and Comparative Examples 1 to 4 prepared with the compounding ratios shown in Table 2 have the following (1) to (4 ) Was carried out, and the results are shown in Table 3.

[0019]

[Table 1]

[0020]

[Table 2]

[Evaluation test] (1) Measurement of protein denaturation rate Using ovalbumin p using high performance liquid chromatography.
The 220 nm absorption peak of ovalbumin when the sample was added to the H7 buffer at a sample concentration of 0.8% was determined as the protein denaturation rate.

[0022]

[Equation 1]

The judgment criteria set are as follows. ⊚: Protein denaturation rate of less than 20% ◯: Protein denaturation rate of 20% or more and less than 40% Δ: Protein denaturation rate of 40% or more and less than 70% ×: Protein denaturation rate of 70% or more (2) Hand roughness test Left and right by 20 panelists An operation of immersing one hand in an aqueous solution having a sample concentration of 5% and a temperature of 40 ° C. and the other hand in hot water of 40 ° C. three times a day for three consecutive days was performed, and the rough condition of the left and right hands was visually observed.

The set judgment criteria are as follows. ⊚: 0 to 2 out of 20 people Rough hands were observed on the sample side. ◯: 3 to 6 out of 20 people Rough hands were observed on the sample side. Δ: 7 to 14 out of 20 samples Roughness was recognized on the sample side.

X: 15 to 20 out of 20 Rough hands were observed on the sample side. (3) Primary skin irritation test An aqueous solution with a sample concentration of 1% 0.2 by 20 panelists
A patch test adhesive bandage impregnated with ml was adhered to the skin for 24 hours, and the irritation was visually determined after the adhesive was removed.

The judgment criteria set are as follows. ◎: 0 to 2 people who showed clear erythema ○: 3 to 6 people who showed clear erythema △: 7 to 14 people who showed clear erythema ×: People who showed clear erythema 15 to 20 people (4) Feel of use 10 panelists evaluated the fineness of foaming and texture by a 5-point method, and judged by the total score.

The judgment criteria set are as follows. ◎: Total points, 40 points or more ○: Total points, 30 points or more and less than 40 points △: Total points, 20 points or more and less than 30 points ×: Total points, less than 20 points

[0028]

[Table 3]

As is apparent from Table 3, the shampoos prepared from the detergent compositions of the present invention (Examples 1 to 5) have low irritation and are less likely to cause rough hands. Moreover, it has excellent usability. In an experiment conducted separately, the shampoos prepared with the detergent compositions of Examples 1 to 5 were excellent in detergency and foamability. [Example 6] A detergent composition having the following composition was prepared as a dishwashing agent.

Mixing ratio (% by weight) (a) N-coconut oil fatty acid acyl-L-glutamate sodium 6 (b) Dipotassium glycyrrhizinate 0.2 (c) Horse chestnut extract (solid content 3%) 3 Lauric acid diethanolamide 3 Polyoxyethylene lauryl ether 5 Lauryl dimethylamine oxide (30%) 2 Methylparaben 0.1 Perfume 0.1 Water Residual This detergent composition was the same as in Examples 1 to 5 in terms of irritation, occurrence of rough skin and feeling of use. An excellent effect was recognized, and it was excellent in cleaning property and foaming property. [Example 7] A detergent composition having the following composition was prepared as a face wash.

Mixing ratio (% by weight) (a) N-myristoyl-L-glutamate 5 (b) Dipotassium glycyrrhizinate 0.2 (c) Horse chestnut extract powder 0.2 Palm oil fatty acid diethanolamide 5 Carboxyvinyl polymer 0. 6 Triethanolamine 0.8 Glycerin 1 Methylparaben 0.1 Perfume 0.1 Water Residual This detergent composition was found to have excellent effects on irritation, occurrence of rough skin and feeling of use, as in Examples 1 to 5. It was excellent in detergency and foamability.

[0032]

Industrial Applicability As described above, the detergent composition of the present invention is less likely to cause rough hands and is excellent in detergency and foamability.

Claims (1)

[Claims] 1. A composition comprising one or more components selected from the following group (a) and one or more components selected from at least one of the following groups (b) and (c): And a cleaning composition. (A) N-acyl amino acids and salts thereof. (B) Glycyrrhizic acid and salts thereof. (C) Horse chestnut extract.