JPS59167600A - ２′−デオキシオキザノシンおよびその製造法 - Google Patents

２′−デオキシオキザノシンおよびその製造法

Info

Publication number
JPS59167600A
JPS59167600A JP58040802A JP4080283A JPS59167600A JP S59167600 A JPS59167600 A JP S59167600A JP 58040802 A JP58040802 A JP 58040802A JP 4080283 A JP4080283 A JP 4080283A JP S59167600 A JPS59167600 A JP S59167600A
Authority
JP
Japan
Prior art keywords
oxanosine
deoxyoxanosine
solvent
reaction
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58040802A
Other languages
English (en)
Japanese (ja)
Other versions
JPH027598B2 (en:Method
Inventor
Hamao Umezawa
梅沢　浜夫
Tomio Takeuchi
富雄 竹内
Masaaki Ishizuka
雅章 石塚
Tomohisa Takita
滝田　智久
Nobuyoshi Shimada
嶋田　信義
Kunimoto Kato
加藤　国基
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP58040802A priority Critical patent/JPS59167600A/ja
Priority to DK144284A priority patent/DK144284A/da
Priority to US06/586,348 priority patent/US4530998A/en
Priority to HU84929A priority patent/HUT35694A/hu
Priority to EP84102551A priority patent/EP0120374B1/en
Priority to AT84102551T priority patent/ATE24519T1/de
Priority to DE8484102551T priority patent/DE3461806D1/de
Priority to GR74066A priority patent/GR81773B/el
Priority to ES530508A priority patent/ES530508A0/es
Priority to CA000449454A priority patent/CA1209132A/en
Priority to ZA841850A priority patent/ZA841850B/xx
Publication of JPS59167600A publication Critical patent/JPS59167600A/ja
Publication of JPH027598B2 publication Critical patent/JPH027598B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/24—Heterocyclic radicals containing oxygen or sulfur as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP58040802A 1983-03-14 1983-03-14 ２′−デオキシオキザノシンおよびその製造法 Granted JPS59167600A (ja)

Priority Applications (11)

Application Number Priority Date Filing Date Title
JP58040802A JPS59167600A (ja) 1983-03-14 1983-03-14 ２′−デオキシオキザノシンおよびその製造法
DK144284A DK144284A (da) 1983-03-14 1984-02-29 2'-desoxyoxanosin, den fremstilling og anvendelse
US06/586,348 US4530998A (en) 1983-03-14 1984-03-05 2'-Deoxyoxanosine
HU84929A HUT35694A (en) 1983-03-14 1984-03-08 Process for producing 2'-deoxy-oxanosine and pharmaceutical compositions containing them
EP84102551A EP0120374B1 (en) 1983-03-14 1984-03-09 2-desoxyoxanosine, a process for the preparation thereof and its use as a medicament
AT84102551T ATE24519T1 (de) 1983-03-14 1984-03-09 2-deoxyoxanosin, verfahren zu seiner herstellung und seine pharmazeutische verwendung.
DE8484102551T DE3461806D1 (en) 1983-03-14 1984-03-09 2-desoxyoxanosine, a process for the preparation thereof and its use as a medicament
GR74066A GR81773B (en:Method) 1983-03-14 1984-03-12
ES530508A ES530508A0 (es) 1983-03-14 1984-03-12 Un metodo de preparar 2'-desoxioxanosina
CA000449454A CA1209132A (en) 1983-03-14 1984-03-13 2'-deoxyoxanocine and processes for preparation thereof
ZA841850A ZA841850B (en) 1983-03-14 1984-03-13 2'-desoxyoxanosine,a process for the preparation thereof and its use as a medicament

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58040802A JPS59167600A (ja) 1983-03-14 1983-03-14 ２′−デオキシオキザノシンおよびその製造法

Publications (2)

Publication Number Publication Date
JPS59167600A true JPS59167600A (ja) 1984-09-21
JPH027598B2 JPH027598B2 (en:Method) 1990-02-19

Family

ID=12590759

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58040802A Granted JPS59167600A (ja) 1983-03-14 1983-03-14 ２′−デオキシオキザノシンおよびその製造法

Country Status (11)

Country Link
US (1) US4530998A (en:Method)
EP (1) EP0120374B1 (en:Method)
JP (1) JPS59167600A (en:Method)
AT (1) ATE24519T1 (en:Method)
CA (1) CA1209132A (en:Method)
DE (1) DE3461806D1 (en:Method)
DK (1) DK144284A (en:Method)
ES (1) ES530508A0 (en:Method)
GR (1) GR81773B (en:Method)
HU (1) HUT35694A (en:Method)
ZA (1) ZA841850B (en:Method)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5243042A (en) * 1990-08-02 1993-09-07 Hoffmann-La Roche Inc. 1-thiaguanosine and process for preparing oxanosine and 1-thiaguanosine
US6822089B1 (en) * 2000-03-29 2004-11-23 Isis Pharmaceuticals, Inc. Preparation of deoxynucleosides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3309359A (en) * 1965-10-22 1967-03-14 Hoffmann La Roche N-mono-acyl-5-fluorocytosine derivatives and process
US3562250A (en) * 1968-07-30 1971-02-09 Akad Wissenschaften Ddr 2',5'-dideoxy-5'-fluoro nucleosides and process for preparing same
US3919193A (en) * 1973-07-06 1975-11-11 Icn Pharmaceuticals 3-Deazaguanosine and derivatives thereof
JPS5788195A (en) * 1980-11-22 1982-06-01 Microbial Chem Res Found Antibiotic, oxanosine, and its preparation

Also Published As

Publication number Publication date
JPH027598B2 (en:Method) 1990-02-19
DK144284A (da) 1984-09-15
ES8506325A1 (es) 1985-07-01
DE3461806D1 (en) 1987-02-05
US4530998A (en) 1985-07-23
HUT35694A (en) 1985-07-29
ATE24519T1 (de) 1987-01-15
EP0120374A1 (en) 1984-10-03
DK144284D0 (da) 1984-02-29
EP0120374B1 (en) 1986-12-30
CA1209132A (en) 1986-08-05
ZA841850B (en) 1985-04-24
GR81773B (en:Method) 1984-12-12
ES530508A0 (es) 1985-07-01

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