JPS591463A - 新規なプロスタグランジンｄ類似化合物 - Google Patents

新規なプロスタグランジンｄ類似化合物

Info

Publication number
JPS591463A
JPS591463A JP57109806A JP10980682A JPS591463A JP S591463 A JPS591463 A JP S591463A JP 57109806 A JP57109806 A JP 57109806A JP 10980682 A JP10980682 A JP 10980682A JP S591463 A JPS591463 A JP S591463A
Authority
JP
Japan
Prior art keywords
compound
compound according
group
formula
deoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57109806A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0314304B2 (enExample
Inventor
Hirohisa Wakatsuka
若塚　弘久
Takashi Yamato
大和　喬
Shinsuke Hashimoto
信介 橋本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority to JP57109806A priority Critical patent/JPS591463A/ja
Priority to DK295583A priority patent/DK295583A/da
Priority to EP83303700A priority patent/EP0098141A3/en
Priority to AU16269/83A priority patent/AU1626983A/en
Priority to ZA834693A priority patent/ZA834693B/xx
Publication of JPS591463A publication Critical patent/JPS591463A/ja
Publication of JPH0314304B2 publication Critical patent/JPH0314304B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP57109806A 1982-06-28 1982-06-28 新規なプロスタグランジンｄ類似化合物 Granted JPS591463A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP57109806A JPS591463A (ja) 1982-06-28 1982-06-28 新規なプロスタグランジンｄ類似化合物
DK295583A DK295583A (da) 1982-06-28 1983-06-27 Fremgangsmaade af prostaglandin-d-analoge
EP83303700A EP0098141A3 (en) 1982-06-28 1983-06-27 Prostaglandin d analogues, process for their preparation and compositions containing them
AU16269/83A AU1626983A (en) 1982-06-28 1983-06-27 Prostaglandin d analogues
ZA834693A ZA834693B (en) 1982-06-28 1983-06-27 Prostaglandin d analogues,process for their preparation and compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57109806A JPS591463A (ja) 1982-06-28 1982-06-28 新規なプロスタグランジンｄ類似化合物

Publications (2)

Publication Number Publication Date
JPS591463A true JPS591463A (ja) 1984-01-06
JPH0314304B2 JPH0314304B2 (enExample) 1991-02-26

Family

ID=14519673

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57109806A Granted JPS591463A (ja) 1982-06-28 1982-06-28 新規なプロスタグランジンｄ類似化合物

Country Status (5)

Country Link
EP (1) EP0098141A3 (enExample)
JP (1) JPS591463A (enExample)
AU (1) AU1626983A (enExample)
DK (1) DK295583A (enExample)
ZA (1) ZA834693B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62236499A (ja) * 1986-02-25 1987-10-16 モエ−エヌスイ　ルシエルシユ 生物学的に活性なポリペプチド、それらの製造方法ならびにそれらを含有する組成物
JP2016533329A (ja) * 2013-09-25 2016-10-27 ウィリアム マーシュ ライス ユニバーシティＷｉｌｌｉａｍ Ｍａｒｓｈ Ｒｉｃｅ Ｕｎｉｖｅｒｓｉｔｙ Δ１２−ｐｇｊ３および関連化合物の合成

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6130554A (ja) * 1984-07-23 1986-02-12 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物のある特定の立体配置を有する異性体及びそれらを有効成分として含有する治療剤
EP0172963A1 (en) * 1984-08-30 1986-03-05 Ono Pharmaceutical Co., Ltd. Prostaglandin analogues, processes for their preparation and compositions containing them
DE3923798A1 (de) * 1989-07-14 1991-01-17 Schering Ag (delta)(pfeil hoch)8(pfeil hoch)-und(delta)(pfeil hoch)9(pfeil hoch)-prostaglandin-derivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
WO2010102078A1 (en) 2009-03-04 2010-09-10 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
US7851504B2 (en) 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
US20060281818A1 (en) * 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
US9328060B2 (en) 2013-10-18 2016-05-03 East Carolina University J-series prostaglandin-ethanolamides as novel therapeutics

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2517773A1 (de) * 1975-04-18 1976-10-28 Schering Ag Neue 11-oxo-prostaglandin-derivate und verfahren zu ihrer herstellung
US4028419A (en) * 1976-01-08 1977-06-07 The Upjoin Company 2-Decarboxy-2-hydroxymethyl-cis-4,5-didehydro-PGE, compounds

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62236499A (ja) * 1986-02-25 1987-10-16 モエ−エヌスイ　ルシエルシユ 生物学的に活性なポリペプチド、それらの製造方法ならびにそれらを含有する組成物
JP2016533329A (ja) * 2013-09-25 2016-10-27 ウィリアム マーシュ ライス ユニバーシティＷｉｌｌｉａｍ Ｍａｒｓｈ Ｒｉｃｅ Ｕｎｉｖｅｒｓｉｔｙ Δ１２−ｐｇｊ３および関連化合物の合成

Also Published As

Publication number Publication date
EP0098141A2 (en) 1984-01-11
EP0098141A3 (en) 1984-08-01
DK295583D0 (da) 1983-06-27
AU1626983A (en) 1984-01-05
DK295583A (da) 1983-12-29
JPH0314304B2 (enExample) 1991-02-26
ZA834693B (en) 1984-03-28

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