JPS585674B2 - アルファヒドロオキシジペプチド受媒質類 - Google Patents
アルファヒドロオキシジペプチド受媒質類Info
- Publication number
- JPS585674B2 JPS585674B2 JP55169206A JP16920680A JPS585674B2 JP S585674 B2 JPS585674 B2 JP S585674B2 JP 55169206 A JP55169206 A JP 55169206A JP 16920680 A JP16920680 A JP 16920680A JP S585674 B2 JPS585674 B2 JP S585674B2
- Authority
- JP
- Japan
- Prior art keywords
- arginine
- lysine
- nitroanilide
- chromogenic
- receiving medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- 125000002887 hydroxy group Chemical group [H]O* 0.000 title description 3
- -1 methylnitrophenyl Chemical group 0.000 claims description 20
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/099,376 US4244865A (en) | 1979-12-03 | 1979-12-03 | α hydroxy tripeptide substrates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56121499A JPS56121499A (en) | 1981-09-24 |
| JPS585674B2 true JPS585674B2 (ja) | 1983-02-01 |
Family
ID=22274710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP55169206A Expired JPS585674B2 (ja) | 1979-12-03 | 1980-12-02 | アルファヒドロオキシジペプチド受媒質類 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US4244865A (cg-RX-API-DMAC10.html) |
| JP (1) | JPS585674B2 (cg-RX-API-DMAC10.html) |
| DE (1) | DE3045430C2 (cg-RX-API-DMAC10.html) |
| FR (1) | FR2471411A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4409140A (en) * | 1979-04-23 | 1983-10-11 | Smith Robert E | Substrates and method for determining enzymes |
| JPS57501234A (cg-RX-API-DMAC10.html) * | 1980-08-25 | 1982-07-15 | ||
| US4448715A (en) * | 1981-11-02 | 1984-05-15 | University Of Miami | Tagged pyroglu-L-Phe-L-Arg derivatives, substrates and assays for kallikrein |
| DE3244030A1 (de) * | 1982-11-27 | 1984-05-30 | Behringwerke Ag, 3550 Marburg | Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung |
| FR2546163B1 (fr) * | 1983-05-16 | 1987-10-09 | Centre Nat Rech Scient | Nouveaux derives acyles hydrosolubles de peptides ou d'amino-acides, leur preparation et leur application |
| JP2516365B2 (ja) * | 1987-05-09 | 1996-07-24 | サンスタ−株式会社 | 歯周疾患検査薬 |
| FR2611205B1 (fr) * | 1987-02-20 | 1990-03-02 | Serbio | Dipeptides, procede de preparation et utilisation dans le dosage de proteases |
| SE8904188D0 (sv) * | 1989-12-12 | 1989-12-12 | Kabivitrum Ab | Chromogenic substrate |
| US5583146A (en) * | 1992-12-02 | 1996-12-10 | Bristol-Myers Squibb Company | Heterocyclic thrombin inhibitors |
| US6200967B1 (en) * | 1996-06-25 | 2001-03-13 | Eli Lilly And Company | Anticoagulant agents |
| WO1997049404A1 (en) * | 1996-06-25 | 1997-12-31 | Eli Lilly And Company | Anticoagulant agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE407058B (sv) * | 1974-12-05 | 1979-03-12 | Kabi Ab | Nya kromogena enzymsubstrat for serinproteaser |
| CH622286A5 (cg-RX-API-DMAC10.html) * | 1975-06-23 | 1981-03-31 | Pentapharm Ag | |
| US4061625A (en) * | 1975-07-11 | 1977-12-06 | Ab Kabi | Novel chromogenic thrombin substrates |
| US4137225A (en) * | 1975-07-11 | 1979-01-30 | Ab Kabi | Novel chromogenic enzyme substrates |
| DE2812943C3 (de) * | 1978-03-23 | 1981-05-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und Reagens zur Bestimmung der biologischen Aktivität von Heparin im Plasma |
-
1979
- 1979-12-03 US US06/099,376 patent/US4244865A/en not_active Expired - Lifetime
-
1980
- 1980-12-02 JP JP55169206A patent/JPS585674B2/ja not_active Expired
- 1980-12-02 DE DE3045430A patent/DE3045430C2/de not_active Expired
- 1980-12-02 FR FR8025572A patent/FR2471411A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS56121499A (en) | 1981-09-24 |
| US4244865A (en) | 1981-01-13 |
| FR2471411A1 (fr) | 1981-06-19 |
| FR2471411B1 (cg-RX-API-DMAC10.html) | 1983-08-05 |
| DE3045430A1 (de) | 1981-09-03 |
| DE3045430C2 (de) | 1983-05-19 |
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