JPS58500610A - アプロチニン−プラスミン錯体からなる新規な医薬，及びその新規な錯体の製造方法 - Google Patents

アプロチニン−プラスミン錯体からなる新規な医薬，及びその新規な錯体の製造方法

Info

Publication number
JPS58500610A
JPS58500610A JP57501460A JP50146082A JPS58500610A JP S58500610 A JPS58500610 A JP S58500610A JP 57501460 A JP57501460 A JP 57501460A JP 50146082 A JP50146082 A JP 50146082A JP S58500610 A JPS58500610 A JP S58500610A
Authority
JP
Japan
Prior art keywords
plasmin
complex
aprotinin
plasminogen
activator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57501460A
Other languages
English (en)
Japanese (ja)
Inventor
ヴエ−レル・エドマン
Original Assignee
シヨアイ・ソシエテ・アノニム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by シヨアイ・ソシエテ・アノニム filed Critical シヨアイ・ソシエテ・アノニム
Publication of JPS58500610A publication Critical patent/JPS58500610A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP57501460A 1981-04-30 1982-04-29 アプロチニン−プラスミン錯体からなる新規な医薬，及びその新規な錯体の製造方法 Pending JPS58500610A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8108681A FR2504921A1 (fr) 1981-04-30 1981-04-30 Medicament nouveau constitue par un complexe aprotinine-plasmine et procede de preparation de ce nouveau complexe
FR81/08681EGB 1981-04-30

Publications (1)

Publication Number Publication Date
JPS58500610A true JPS58500610A (ja) 1983-04-21

Family

ID=9257969

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57501460A Pending JPS58500610A (ja) 1981-04-30 1982-04-29 アプロチニン−プラスミン錯体からなる新規な医薬，及びその新規な錯体の製造方法

Country Status (4)

Country Link
EP (1) EP0077796A1 (enrdf_load_stackoverflow)
JP (1) JPS58500610A (enrdf_load_stackoverflow)
FR (1) FR2504921A1 (enrdf_load_stackoverflow)
WO (1) WO1982003772A1 (enrdf_load_stackoverflow)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63239300A (ja) * 1987-03-27 1988-10-05 Green Cross Corp:The プラスミノゲンの製造方法
JPH0193535A (ja) * 1987-10-01 1989-04-12 Green Cross Corp:The 線溶活性増強剤
JPH0283335A (ja) * 1987-09-18 1990-03-23 Thrombosis Res Trust 血栓溶解剤

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3119157A1 (de) * 1981-05-14 1982-12-09 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung von und danach hergestelltes plasminogen
DE19903693A1 (de) * 1998-04-24 1999-10-28 Centeon Pharma Gmbh Protease zur Aktivierung des Gerinnungsfaktors VII
DE10023923A1 (de) 1999-06-10 2000-12-14 Aventis Behring Gmbh Verfahren zur Bestimmung der Aktivität der Faktor VII-aktivierenden Protease aus Proteinlösungen
US7202066B2 (en) * 2002-01-29 2007-04-10 Carrington Laboratories, Inc. Combination of a growth factor and a protease enzyme
CN117568445B (zh) * 2024-01-18 2024-04-09 西南交通大学 一种tat、pic复合质控品的制备方法及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7602846A (nl) * 1976-03-18 1977-09-20 Leuven Res & Dev Vzw Antiplasmine en een antiserum daartegen.

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63239300A (ja) * 1987-03-27 1988-10-05 Green Cross Corp:The プラスミノゲンの製造方法
JPH0283335A (ja) * 1987-09-18 1990-03-23 Thrombosis Res Trust 血栓溶解剤
JPH0193535A (ja) * 1987-10-01 1989-04-12 Green Cross Corp:The 線溶活性増強剤

Also Published As

Publication number Publication date
WO1982003772A1 (en) 1982-11-11
EP0077796A1 (fr) 1983-05-04
FR2504921B1 (enrdf_load_stackoverflow) 1985-05-17
FR2504921A1 (fr) 1982-11-05

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