JPS5846006A - Acaricide - Google Patents

Abstract

PURPOSE:A safe acaricide comprising a blend of a macrotetrolide antibiotic and phosalone as an active ingredient, showing more improved acaricidal and controlling effect especially on Panonychus citri McGregor than their single use, having no phytotoxicity to fruit trees. CONSTITUTION:One ore more of macrotetrolide antibiotics shown by the formula (R1-R4 are lower alkyl) used as insecticides or acaricides are blended with phosalone{=S-[(6-chloro-2-oxo-3-benzoxazolinyl)methyl]diethylphosphoro thiolothionate}having improved controlling effect on various kinds of juice-absorbing noxious insects such as cockroaches and mastricatory noxious insects such as Caloptila theivora Walsingham, etc. in a weight ratio of the former to the latter of 1pts.wt. to 0.1-10pts.wt. The blend is blended with various kinds of carriers, auxiliaries, etc. and prepared into the form of emulsion, wettable powder, etc. for use.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention provides macrotetrolide
ide) and at least one type of antibiotic of the 13-[, (6
-Chloro-2-oxo-6-benzoxazolinyl)methyl] diethyl phosphorothiorothionate (common name: "phosalone") and a mixture thereof as an active ingredient. The purpose is to provide a new acaricide that can effectively control various types of mites.

The macrotetrolide antibiotic constituting the acaricide of the present invention has a structural formula (wherein Rls R2, R5 and R4 each represent a lower alkyl group).

The use of a combination of macrotetrolide antibiotics and organophosphorus compounds as an insecticide and acaricide was approved in 1973.
It is described in Publication No. 9-6656. however,
The Boki publication does not specifically describe specific combinations and their effects as in the present invention.

The acaricide of the present invention has an extremely superior acaricidal effect, especially against M. mites, when compared to the insecticidal and acaricidal agents described in the above-mentioned publication.

The present invention is thus a novel acaricide that acts specifically against specific mites and exhibits excellent control effects.

In recent years, mites have become a problem as well as various pests of satsatsu vegetables and fruit trees, and acaricides have been actively developed. However, at present, there are very few acaricides with high practicality due to various reasons. Under these circumstances, new acaricides not only have excellent acaricidal effects, but also require fast-acting properties from the standpoint of safety and health when spraying the acaricide or ingesting cultivated crops. It is desired that the substance has the following properties, has no residual toxicity, and has low toxicity to humans and animals. Furthermore, on the other hand, it is also required to have a suitable residual effect.

In order to develop acaricides that meet these requirements, the present inventors tested various agents from Cypress and made extensive studies. As a result, by applying a mixture of one or more macrotetrolide antibiotics, which have been traditionally used as insecticides or acaricides, and phosalon, it is possible to treat Da-a in fruit trees. The present invention was completed based on the discovery that it is a chemical that exhibits a specifically high pesticidal effect and can be used extremely safely without causing any chemical damage to fruit trees.

The macrotetrolide antibiotic used in the present invention is
It has already been put into practical use as an insecticide and acaricide containing a vorinactin complex. However, although these antibiotics have a fairly high control effect against Goo 14, their duration is short and their insecticidal power against various pests is insufficient compared to their acaricidal effect. Therefore, in order to compensate for this, it is currently being put into practical use as a mixture with 0POB8, an acaricide, or as a mixture with 62IBPMO, an insecticide. In addition, one of the active ingredients, Hosalon, is effective against various sweat-absorbing pests such as aphids, as well as tea-like moths, tea-like spiders, and nha! It is useful as an insecticide, showing excellent control effects against chewing insect pests such as yellow and yellow ladybugs. However, a sufficient acaricidal effect cannot be expected when used alone.

The acaricide of the present invention can fully exhibit the inherent advantages of the above-mentioned macrotetratropic antibiotics and phosalon.

The active ingredients mutually enhance each other and fully exert the acaricidal effect that could not be expected with each single agent, and the effect is synergistically exerted far beyond what those skilled in the art expected. . Such acaricide of the present invention is disclosed in Japanese Patent Publication No. 1973-
Compared to the insecticide and acaricide described in Japanese Patent No. 6656, the acaricide of the present invention is particularly superior in the following manner.

In other words, the drug of the present invention has an effect equal to or better than the comparative drug against green peach beetles, mites, etc.; The drug of the present invention is significantly superior to comparative drugs, and its effects are exerted with remarkable synergism. Therefore, the acaricide of the present invention can significantly reduce the dosage compared to when macrotetrolide antibiotics and phosalon are applied alone, so it is not only suitable for use on fruit trees, but also on fruit trees and other plants. It does not cause any chemical damage to useful crops, and can be used safely for humans and livestock.

The macrotetrolide antibiotic, which is one of the active ingredients of the acaricide of the present invention, is one of the active ingredients of the acaricide of the present invention.
Vol. 38, pp. 1445-144B (1955), Vol. 45, pp. 129-13a7 (1942), Vol. 45, pp. 620-630 (1962), Special Publication No. 46 -281
It can also be produced by the methods described in Japanese Patent Publication No. 00 and Japanese Patent Publication No. 49-1842, or by the method of culturing Streptomyces naureus (FIRM-P Group 25S). Due to differences in manufacturing methods or purification processes, these antibiotics may have substances that are considered to be stereoisomers with the same chemical formula but slightly different physical and chemical properties1; No significant difference was observed in Kj of the present invention for any substance.
IP can be used without distinction.

The blending ratio of the active ingredients of the acaricide of the present invention is
Add Phosaron (11 parts by weight) to 1 part by weight of a-ride antibiotic.
It is used in a proportion of ~10 parts by weight, but the amount can be increased or decreased as necessary. In addition, if used in combination with other insecticides, acaricides, fungicides, plant growth regulators, etc., it can be effectively used as a labor-saving pest control agent.

The acaricide of the present invention can be used as a powder, emulsion, irrigation agent, or
It can be prepared and used in an appropriate form such as an oil solution or a fine granule. As a carrier, it is possible to use either a solid or a liquid carrier, as long as it is commonly used in agricultural medicines.It is not limited to a specific color, but liquid carriers include kijirol, cyclohexanone, methyl ethyl ketone, etc. Examples of solid carriers include kaolin, Merck,
Examples include bentonite, diatomaceous earth, silica, and clay. In addition, auxiliary agents used in Takaen's oral medicines, such as emulsifiers, wetting agents, spreading agents, dispersants, etc., can be used as appropriate.

Next, examples of the acaricide of the present invention will be given, but the present invention is not limited to the following examples. In the following examples, all parts indicate parts by weight. Ta. In the examples, compounds (1) to (5) represent R1-R4 of the general formula
The following are shown below.

Compound (1) R chant==R2-R5-R4-OH5 Compound ■ R1-R2=ER1mOH5R4-=02H502
Part 5) R1-R2=OH5RyxR4zO2 Part 5
Compound (4) R1=OJ R4-R5-R4=0
2H5 compound (5) R1-R2-R1-R4-02
115 Example 1 10 parts of emulsion compound (5), 20 parts of Phosalon, 15 parts of Nucalgen 2115-PO (trade name of a surfactant manufactured by Monomoto Yushi Kogyo, same hereinafter) and 55 parts of Kijirole were uniformly mixed. to obtain an emulsion.

Example 2 Emulsion 8 parts of mixture of compounds (1) to (5), Hosaro 15
Q @Il, 2z -12kgey2115-PO1
5 parts and 47 parts of Kijirole were uniformly mixed to obtain an emulsion.

Example 5 Wettable powder compound (S) tO parts, 40 parts of phosalone, 2 parts of polyvinyl alcohol, 10 parts of sodium ligninsulfonate, and 5.3 parts of clay are uniformly mixed and pulverized to obtain an irrigation agent.

Example 4 Wettable powder Compound (1) - Compound (10 parts of the mixture, Phosalon S
o parts, ;tr 2 parts of libinyl alcohol, 10 parts of sodium lignin sulfonate, and 48 parts of clay are uniformly mixed and pulverized to obtain an irrigation agent.

Next, the usefulness of the acaricide of the present invention will be explained by giving test examples.

Test Example 1 Test for control effect against adult spider mites Gel-like agar is poured into a glass petri dish with a diameter of 93, and mandarin orange leaves cut to a diameter of 5 all are floated thereon. There, 10 female adult spider mites that have been reared for generations were placed.
Connect them one by one. Then, a dilute solution of a predetermined concentration of an irrigation agent prepared according to Example 3 was sprayed at 5 times per shear using a rotary spray tower (manufactured by Mizuha Rika Co., Ltd.), and after 48 hours, the number of living and dead citrus spider mites was determined. The 0 test to determine the mortality rate (-) was carried out at 5 V per concentration, and the average mortality rate was calculated. The results are shown in Table 3.

Table 1 rMIPJ is 0.0-diethyl o-3-methyl-4-nitrophenylphosphorothioate t-, and [
PAPJ is S-(α-ethoxycarbonyl)benzyl]
0.0-'; indicates methyl phosphorodithioate.

Test Example 2 Control effect test on orange spider mites A diluted solution of a predetermined concentration of an irrigation agent prepared according to Example 5 was sprayed at a rate of 200ml per pot to potted Satsuma oranges (approx. 60 countries) where orange spider mites had grown. After that, the number of citrus spider mites occurring every predetermined number of days was investigated to determine the control side). This test was conducted using three pots per concentration, and the average vjWk value was calculated. The results are shown in Table 2.

Claims (1)

[Claims] (In the formula, "1s" 2, R5 and R4 each represent a lower alkyl group) and at least one macrotetrolide antibiotic and 8-[(6-chloro-2-oxo-3-petrol). /zuoxazolinyl) methyl] A miticide patented as containing a mixture with diethyl phosphorothiolothionate as an active ingredient.