JPS5824596A - セノデオキシコリン酸誘導体、その製造法およびそれを有効成分とする医薬組成物 - Google Patents

セノデオキシコリン酸誘導体、その製造法およびそれを有効成分とする医薬組成物

Info

Publication number
JPS5824596A
JPS5824596A JP57124984A JP12498482A JPS5824596A JP S5824596 A JPS5824596 A JP S5824596A JP 57124984 A JP57124984 A JP 57124984A JP 12498482 A JP12498482 A JP 12498482A JP S5824596 A JPS5824596 A JP S5824596A
Authority
JP
Japan
Prior art keywords
acid
carbon atoms
carboxylic acid
general formula
acid residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57124984A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6159638B2 (enExample
Inventor
カルロ・スコラスチコ
チエサレ・シルトリ
ダビツド・クリチエフスキ−
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JPS5824596A publication Critical patent/JPS5824596A/ja
Publication of JPS6159638B2 publication Critical patent/JPS6159638B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP57124984A 1981-07-24 1982-07-17 セノデオキシコリン酸誘導体、その製造法およびそれを有効成分とする医薬組成物 Granted JPS5824596A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT23109A/81 1981-07-24
IT23109/81A IT1167479B (it) 1981-07-24 1981-07-24 Derivati dell'acido chenodesossicolico

Publications (2)

Publication Number Publication Date
JPS5824596A true JPS5824596A (ja) 1983-02-14
JPS6159638B2 JPS6159638B2 (enExample) 1986-12-17

Family

ID=11203872

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57124984A Granted JPS5824596A (ja) 1981-07-24 1982-07-17 セノデオキシコリン酸誘導体、その製造法およびそれを有効成分とする医薬組成物

Country Status (6)

Country Link
US (1) US4439366A (enExample)
JP (1) JPS5824596A (enExample)
DE (1) DE3225529C2 (enExample)
FR (1) FR2510558A1 (enExample)
GB (1) GB2105723B (enExample)
IT (1) IT1167479B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1221734B (it) * 1983-02-24 1990-07-12 Schiena Michele Giuseppe Di Ursodesossicolico solfato acido sale sodico
DE3430366A1 (de) * 1983-08-19 1985-03-07 Kao Corp., Tokio/Tokyo Mittel zur aufloesung von gallensteinen
IT1199843B (it) * 1986-12-05 1989-01-05 Gipharmex Spa Complesso di prodotti per il trattamento rapido e non invasivo della calcolosi biliare
JPS6411910A (en) * 1987-07-06 1989-01-17 Nippon Dia Clevite Co Carbon container for sintering
JPH0331295U (enExample) * 1989-07-28 1991-03-27
AU664059B2 (en) * 1991-12-20 1995-11-02 Hoechst Aktiengesellschaft Ethylenically unsaturated bile acid derivatives, processes for their preparation and precursors
IL142650A (en) * 1998-04-08 2007-06-03 Galmed Int Ltd Use of bile acid conjugates or bile salts and fatty acids or fatty acids in the preparation of pharmaceuticals for lowering cholesterol, for the treatment of fatty liver and for the treatment of hyperglycemia and diabetes
IL123998A (en) * 1998-04-08 2004-09-27 Galmed Int Ltd Conjugates of bile salts and pharmaceutical preparations containing them
US8975246B2 (en) 2001-04-17 2015-03-10 Galmed Research And Development Ltd. Bile acid or bile salt fatty acid conjugates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833620A (en) * 1972-11-16 1974-09-03 Intellectual Property Dev Corp Production of chenodeoxycholic acid
US3969503A (en) * 1975-10-02 1976-07-13 Intellectual Property Development Corporation Compositions and methods useful in rendering lithogenic mammalian bile non-lithogenic
IT1165252B (it) * 1979-07-12 1987-04-22 Blasinachim Spa Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati

Also Published As

Publication number Publication date
DE3225529C2 (de) 1985-03-28
FR2510558B1 (enExample) 1985-05-17
FR2510558A1 (fr) 1983-02-04
DE3225529A1 (de) 1983-02-10
JPS6159638B2 (enExample) 1986-12-17
GB2105723A (en) 1983-03-30
IT1167479B (it) 1987-05-13
US4439366A (en) 1984-03-27
IT8123109A0 (it) 1981-07-24
GB2105723B (en) 1985-06-26
IT8123109A1 (it) 1983-01-24

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