JPS58187860A - 免疫学的凝集反応の光学的測定方法 - Google Patents
免疫学的凝集反応の光学的測定方法Info
- Publication number
- JPS58187860A JPS58187860A JP7013682A JP7013682A JPS58187860A JP S58187860 A JPS58187860 A JP S58187860A JP 7013682 A JP7013682 A JP 7013682A JP 7013682 A JP7013682 A JP 7013682A JP S58187860 A JPS58187860 A JP S58187860A
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- reaction
- solution
- antibody
- agglutination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000004520 agglutination Effects 0.000 title claims abstract description 21
- 238000005259 measurement Methods 0.000 title description 14
- 230000003287 optical effect Effects 0.000 title description 8
- 238000006243 chemical reaction Methods 0.000 claims abstract description 32
- 238000000034 method Methods 0.000 claims abstract description 22
- 239000000427 antigen Substances 0.000 claims abstract description 19
- 102000036639 antigens Human genes 0.000 claims abstract description 19
- 108091007433 antigens Proteins 0.000 claims abstract description 19
- 239000002245 particle Substances 0.000 claims abstract description 14
- 239000011541 reaction mixture Substances 0.000 claims abstract description 6
- 230000001900 immune effect Effects 0.000 claims description 12
- 230000010355 oscillation Effects 0.000 claims description 2
- 239000004065 semiconductor Substances 0.000 claims description 2
- 230000001678 irradiating effect Effects 0.000 abstract 1
- 238000011896 sensitive detection Methods 0.000 abstract 1
- 238000000149 argon plasma sintering Methods 0.000 description 13
- 230000002776 aggregation Effects 0.000 description 12
- 238000004220 aggregation Methods 0.000 description 9
- 239000004816 latex Substances 0.000 description 9
- 229920000126 latex Polymers 0.000 description 9
- 239000007788 liquid Substances 0.000 description 8
- 238000001514 detection method Methods 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 230000035945 sensitivity Effects 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 238000005054 agglomeration Methods 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 238000000691 measurement method Methods 0.000 description 3
- 238000011002 quantification Methods 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 229920000620 organic polymer Polymers 0.000 description 2
- 101710098119 Chaperonin GroEL 2 Proteins 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 238000011481 absorbance measurement Methods 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000007720 emulsion polymerization reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 238000007667 floating Methods 0.000 description 1
- 229940106780 human fibrinogen Drugs 0.000 description 1
- 229910052809 inorganic oxide Inorganic materials 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 238000005375 photometry Methods 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 238000007781 pre-processing Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 229920003048 styrene butadiene rubber Polymers 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7013682A JPS58187860A (ja) | 1982-04-26 | 1982-04-26 | 免疫学的凝集反応の光学的測定方法 |
| US06/481,961 US4766083A (en) | 1982-04-04 | 1983-04-04 | Method for the photometric determination of biological agglutination |
| EP83103297A EP0091636B1 (en) | 1982-04-04 | 1983-04-05 | Method for the photometric determination of biological agglutination |
| DE8383103297T DE3381979D1 (de) | 1982-04-04 | 1983-04-05 | Verfahren zur photometrischen bestimmung biologischer agglutinaten. |
| AT83103297T ATE58245T1 (de) | 1982-04-04 | 1983-04-05 | Verfahren zur photometrischen bestimmung biologischer agglutinaten. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7013682A JPS58187860A (ja) | 1982-04-26 | 1982-04-26 | 免疫学的凝集反応の光学的測定方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58187860A true JPS58187860A (ja) | 1983-11-02 |
| JPH0421821B2 JPH0421821B2 (enrdf_load_stackoverflow) | 1992-04-14 |
Family
ID=13422846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7013682A Granted JPS58187860A (ja) | 1982-04-04 | 1982-04-26 | 免疫学的凝集反応の光学的測定方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58187860A (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4960983A (en) * | 1987-09-28 | 1990-10-02 | Mitsubishi Denki Kabushiki Kaisha | Noncontact type IC card and system for noncontact transfer of information using the same |
| US5198369A (en) * | 1990-04-25 | 1993-03-30 | Canon Kabushiki Kaisha | Sample measuring method using agglomeration reaction of microcarriers |
| KR101485233B1 (ko) * | 2010-06-04 | 2015-01-22 | 토루 오바타 | 겔 입자 측정 장치 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54109494A (en) * | 1978-02-16 | 1979-08-28 | Teikoku Hormone Mfg Co Ltd | Method of measuring antigennantibody reaction |
| JPS57175957A (en) * | 1981-04-24 | 1982-10-29 | Chugai Pharmaceut Co Ltd | Measuring method and device for antigen- antibody reaction |
| JPS5896251A (ja) * | 1981-12-04 | 1983-06-08 | Asahi Medical Kk | 抗原又は抗体の測定方法および測定用試薬 |
-
1982
- 1982-04-26 JP JP7013682A patent/JPS58187860A/ja active Granted
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54109494A (en) * | 1978-02-16 | 1979-08-28 | Teikoku Hormone Mfg Co Ltd | Method of measuring antigennantibody reaction |
| JPS57175957A (en) * | 1981-04-24 | 1982-10-29 | Chugai Pharmaceut Co Ltd | Measuring method and device for antigen- antibody reaction |
| JPS5896251A (ja) * | 1981-12-04 | 1983-06-08 | Asahi Medical Kk | 抗原又は抗体の測定方法および測定用試薬 |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4960983A (en) * | 1987-09-28 | 1990-10-02 | Mitsubishi Denki Kabushiki Kaisha | Noncontact type IC card and system for noncontact transfer of information using the same |
| US5198369A (en) * | 1990-04-25 | 1993-03-30 | Canon Kabushiki Kaisha | Sample measuring method using agglomeration reaction of microcarriers |
| KR101485233B1 (ko) * | 2010-06-04 | 2015-01-22 | 토루 오바타 | 겔 입자 측정 장치 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0421821B2 (enrdf_load_stackoverflow) | 1992-04-14 |
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