JPS58159415A - 原虫のライフサイクル阻害方法 - Google Patents
原虫のライフサイクル阻害方法Info
- Publication number
- JPS58159415A JPS58159415A JP4334982A JP4334982A JPS58159415A JP S58159415 A JPS58159415 A JP S58159415A JP 4334982 A JP4334982 A JP 4334982A JP 4334982 A JP4334982 A JP 4334982A JP S58159415 A JPS58159415 A JP S58159415A
- Authority
- JP
- Japan
- Prior art keywords
- chicken
- chickens
- poultry
- protozoa
- life cycle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000005764 inhibitory process Effects 0.000 title 1
- 208000024891 symptom Diseases 0.000 claims abstract description 8
- 239000004721 Polyphenylene oxide Substances 0.000 claims abstract description 5
- 239000003242 anti bacterial agent Substances 0.000 claims abstract description 5
- 229940088710 antibiotic agent Drugs 0.000 claims abstract description 5
- 229920000570 polyether Polymers 0.000 claims abstract description 5
- 230000028070 sporulation Effects 0.000 claims abstract description 5
- 150000003839 salts Chemical class 0.000 claims abstract description 3
- 241000287828 Gallus gallus Species 0.000 claims description 47
- 235000013330 chicken meat Nutrition 0.000 claims description 47
- 229940079593 drug Drugs 0.000 claims description 11
- 239000003814 drug Substances 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 9
- 230000002401 inhibitory effect Effects 0.000 claims description 4
- 241000189662 Calla Species 0.000 claims description 3
- 230000001747 exhibiting effect Effects 0.000 claims 1
- ZZORFUFYDOWNEF-UHFFFAOYSA-N sulfadimethoxine Chemical compound COC1=NC(OC)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 ZZORFUFYDOWNEF-UHFFFAOYSA-N 0.000 abstract description 7
- 244000144977 poultry Species 0.000 abstract description 6
- 229960000973 sulfadimethoxine Drugs 0.000 abstract description 5
- 241001538374 Leucocytozoon caulleryi Species 0.000 abstract description 4
- KQXDHUJYNAXLNZ-XQSDOZFQSA-N Salinomycin Chemical compound O1[C@@H]([C@@H](CC)C(O)=O)CC[C@H](C)[C@@H]1[C@@H](C)[C@H](O)[C@H](C)C(=O)[C@H](CC)[C@@H]1[C@@H](C)C[C@@H](C)[C@@]2(C=C[C@@H](O)[C@@]3(O[C@@](C)(CC3)[C@@H]3O[C@@H](C)[C@@](O)(CC)CC3)O2)O1 KQXDHUJYNAXLNZ-XQSDOZFQSA-N 0.000 abstract description 3
- 239000004189 Salinomycin Substances 0.000 abstract description 3
- 229960001548 salinomycin Drugs 0.000 abstract description 3
- 235000019378 salinomycin Nutrition 0.000 abstract description 3
- 230000005540 biological transmission Effects 0.000 abstract description 2
- 230000017259 schizogony Effects 0.000 abstract description 2
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 241000238631 Hexapoda Species 0.000 abstract 1
- 241001470497 Leucocytozoon Species 0.000 abstract 1
- 230000005002 sporogony Effects 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 description 10
- 239000008280 blood Substances 0.000 description 10
- 230000005005 gametogony Effects 0.000 description 5
- 210000003046 sporozoite Anatomy 0.000 description 5
- 239000000427 antigen Substances 0.000 description 4
- 102000036639 antigens Human genes 0.000 description 4
- 108091007433 antigens Proteins 0.000 description 4
- 210000003743 erythrocyte Anatomy 0.000 description 4
- 230000012010 growth Effects 0.000 description 4
- 210000003936 merozoite Anatomy 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 238000011081 inoculation Methods 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- BKZOUCVNTCLNFF-IGXZVFLKSA-N (2s)-2-[(2r,3r,4s,5r,6s)-2-hydroxy-6-[(1s)-1-[(2s,5r,7s,8r,9s)-2-[(2r,5s)-5-[(2r,3s,4r,5r)-5-[(2s,3s,4s,5r,6s)-6-hydroxy-4-methoxy-3,5,6-trimethyloxan-2-yl]-4-methoxy-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-7-methoxy-2,8-dimethyl-1,10-dioxaspiro[4.5]dec Chemical compound O([C@@H]1[C@@H]2O[C@H]([C@@H](C)[C@H]2OC)[C@@]2(C)O[C@H](CC2)[C@@]2(C)O[C@]3(O[C@@H]([C@H](C)[C@@H](OC)C3)[C@@H](C)[C@@H]3[C@@H]([C@H](OC)[C@@H](C)[C@](O)([C@H](C)C(O)=O)O3)C)CC2)[C@](C)(O)[C@H](C)[C@@H](OC)[C@@H]1C BKZOUCVNTCLNFF-IGXZVFLKSA-N 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 2
- BKZOUCVNTCLNFF-UHFFFAOYSA-N Lonomycin Natural products COC1C(C)C(C2(C)OC(CC2)C2(C)OC3(OC(C(C)C(OC)C3)C(C)C3C(C(OC)C(C)C(O)(C(C)C(O)=O)O3)C)CC2)OC1C1OC(C)(O)C(C)C(OC)C1C BKZOUCVNTCLNFF-UHFFFAOYSA-N 0.000 description 2
- 208000009182 Parasitemia Diseases 0.000 description 2
- 208000030852 Parasitic disease Diseases 0.000 description 2
- 208000007502 anemia Diseases 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000000973 gametocyte Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000000052 microgametocyte Anatomy 0.000 description 2
- 235000013594 poultry meat Nutrition 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 230000001850 reproductive effect Effects 0.000 description 2
- 210000004215 spore Anatomy 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 241000282693 Cercopithecidae Species 0.000 description 1
- 240000003173 Drymaria cordata Species 0.000 description 1
- 238000002738 Giemsa staining Methods 0.000 description 1
- 229930191564 Monensin Natural products 0.000 description 1
- GAOZTHIDHYLHMS-UHFFFAOYSA-N Monensin A Natural products O1C(CC)(C2C(CC(O2)C2C(CC(C)C(O)(CO)O2)C)C)CCC1C(O1)(C)CCC21CC(O)C(C)C(C(C)C(OC)C(C)C(O)=O)O2 GAOZTHIDHYLHMS-UHFFFAOYSA-N 0.000 description 1
- 240000000249 Morus alba Species 0.000 description 1
- 235000008708 Morus alba Nutrition 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 230000011681 asexual reproduction Effects 0.000 description 1
- 238000013465 asexual reproduction Methods 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000016784 immunoglobulin production Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229960005358 monensin Drugs 0.000 description 1
- GAOZTHIDHYLHMS-KEOBGNEYSA-N monensin A Chemical compound C([C@@](O1)(C)[C@H]2CC[C@@](O2)(CC)[C@H]2[C@H](C[C@@H](O2)[C@@H]2[C@H](C[C@@H](C)[C@](O)(CO)O2)C)C)C[C@@]21C[C@H](O)[C@@H](C)[C@@H]([C@@H](C)[C@@H](OC)[C@H](C)C(O)=O)O2 GAOZTHIDHYLHMS-KEOBGNEYSA-N 0.000 description 1
- 210000000865 mononuclear phagocyte system Anatomy 0.000 description 1
- 210000003250 oocyst Anatomy 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 239000002460 polyether antibiotic agent Substances 0.000 description 1
- 210000004021 protozoal spore Anatomy 0.000 description 1
- 244000000040 protozoan parasite Species 0.000 description 1
- 230000000384 rearing effect Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000033458 reproduction Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 210000001563 schizont Anatomy 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- XOIQMTLWECTKJL-FBZUZRIGSA-M sodium;(2s,3r,4s)-4-[(2s,5r,7s,8r,9s)-2-[(2r,5s)-5-ethyl-5-[(2r,3s,5r)-5-[(2s,3s,5r,6r)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]oxolan-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-3-methoxy-2-methylpentanoate Chemical compound [Na+].C([C@@](O1)(C)[C@H]2CC[C@@](O2)(CC)[C@H]2[C@H](C[C@@H](O2)[C@@H]2[C@H](C[C@@H](C)[C@](O)(CO)O2)C)C)C[C@@]21C[C@H](O)[C@@H](C)[C@@H]([C@@H](C)[C@@H](OC)[C@H](C)C([O-])=O)O2 XOIQMTLWECTKJL-FBZUZRIGSA-M 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4334982A JPS58159415A (ja) | 1982-03-18 | 1982-03-18 | 原虫のライフサイクル阻害方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4334982A JPS58159415A (ja) | 1982-03-18 | 1982-03-18 | 原虫のライフサイクル阻害方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58159415A true JPS58159415A (ja) | 1983-09-21 |
| JPH0155248B2 JPH0155248B2 (https=) | 1989-11-22 |
Family
ID=12661366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4334982A Granted JPS58159415A (ja) | 1982-03-18 | 1982-03-18 | 原虫のライフサイクル阻害方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58159415A (https=) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52102176A (en) * | 1976-02-21 | 1977-08-26 | Kaken Pharmaceut Co Ltd | Agent for improving feed stuff efficiency |
-
1982
- 1982-03-18 JP JP4334982A patent/JPS58159415A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52102176A (en) * | 1976-02-21 | 1977-08-26 | Kaken Pharmaceut Co Ltd | Agent for improving feed stuff efficiency |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0155248B2 (https=) | 1989-11-22 |
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