JPS581118B2 - １５↓−置換↓−ω↓−ペンタノルプロスタグランジン誘導体 - Google Patents

１５↓−置換↓−ω↓−ペンタノルプロスタグランジン誘導体

Info

Publication number
JPS581118B2
JPS581118B2 JP53070706A JP7070678A JPS581118B2 JP S581118 B2 JPS581118 B2 JP S581118B2 JP 53070706 A JP53070706 A JP 53070706A JP 7070678 A JP7070678 A JP 7070678A JP S581118 B2 JPS581118 B2 JP S581118B2
Authority
JP
Japan
Prior art keywords
phenyl
trans
hydroxy
lactone
tetrahydropyran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP53070706A
Other languages
English (en)
Japanese (ja)
Other versions
JPS545954A (en
Inventor
トーマス・ケン・シヤーフ
ハンス・ユルゲン・エルンスト・ヘス
マイケル・ロス・ジヨンソン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Original Assignee
Pfizer Corp Belgium
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium filed Critical Pfizer Corp Belgium
Publication of JPS545954A publication Critical patent/JPS545954A/ja
Publication of JPS581118B2 publication Critical patent/JPS581118B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP53070706A 1977-06-13 1978-06-12 １５↓−置換↓−ω↓−ペンタノルプロスタグランジン誘導体 Expired JPS581118B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/805,879 US4404372A (en) 1977-06-13 1977-06-13 15-Substituted-ω-pentanorprostaglandin derivatives

Publications (2)

Publication Number Publication Date
JPS545954A JPS545954A (en) 1979-01-17
JPS581118B2 true JPS581118B2 (ja) 1983-01-10

Family

ID=25192775

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53070706A Expired JPS581118B2 (ja) 1977-06-13 1978-06-12 １５↓−置換↓−ω↓−ペンタノルプロスタグランジン誘導体

Country Status (11)

Country Link
US (1) US4404372A (en, 2012)
JP (1) JPS581118B2 (en, 2012)
BE (1) BE868033A (en, 2012)
DE (1) DE2825855C3 (en, 2012)
DK (1) DK262478A (en, 2012)
FR (1) FR2394539A1 (en, 2012)
GB (1) GB2000128B (en, 2012)
IE (1) IE47626B1 (en, 2012)
IT (1) IT1096628B (en, 2012)
LU (1) LU79801A1 (en, 2012)
NL (1) NL171892C (en, 2012)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK523378A (da) * 1978-01-16 1979-07-17 Pfizer Fremgangsmaade til fremstilling af n-(tetrazol-5-yl) prostaglandin-carboxamider eller salte deraf
GB8329559D0 (en) * 1983-11-04 1983-12-07 Erba Farmitalia Furyl derivatives of 16-substituted prostaglandins preparations
US6476064B1 (en) 2001-06-13 2002-11-05 Allergan, Inc. Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents
WO2003074481A2 (en) * 2002-03-01 2003-09-12 Allergan, Inc. Preparation of prostamides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3987087A (en) * 1971-07-29 1976-10-19 The Upjohn Company Phenyl-substituted prostaglandin-f type analogs
US3954741A (en) * 1972-06-07 1976-05-04 Pfizer Inc. N-substituted prostaglandin carboxamides
US3971826A (en) * 1972-07-13 1976-07-27 Pfizer Inc. 15-Substituted-ω-pentanorprostaglandins
US3987085A (en) * 1972-09-15 1976-10-19 The Upjohn Company 8β,11β,12α-PGF2.sub.α compounds
US3984424A (en) * 1972-11-08 1976-10-05 Pfizer Inc. P-biphenyl esters of 15-substituted-ω-pentanorprostaglandins
IL43571A (en) * 1972-11-08 1977-08-31 Pfizer Omega-pentanorprostaglandins and their preparation
US3932389A (en) * 1974-12-11 1976-01-13 Pfizer Inc. 2-Descarboxy-2-(tetrazol-5-yl)-11-desoxy-15-substituted-.omega.-pentanorprostaglandins

Also Published As

Publication number Publication date
NL7805378A (nl) 1978-12-15
DE2825855B2 (en, 2012) 1980-11-06
IT1096628B (it) 1985-08-26
IT7824472A0 (it) 1978-06-12
IE47626B1 (en) 1984-05-16
NL171892B (nl) 1983-01-03
US4404372A (en) 1983-09-13
NL171892C (nl) 1983-06-01
GB2000128B (en) 1982-02-03
IE781181L (en) 1978-12-13
LU79801A1 (fr) 1980-01-22
BE868033A (fr) 1978-12-12
DE2825855A1 (de) 1978-12-14
FR2394539B1 (en, 2012) 1980-10-24
FR2394539A1 (fr) 1979-01-12
GB2000128A (en) 1979-01-04
JPS545954A (en) 1979-01-17
DK262478A (da) 1978-12-14
DE2825855C3 (de) 1981-10-08

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