JPS581000A - ４α，５α−エポキシ−３，２０−ジオキソプレグナン−２α，１６α−ジカルボニトリル，その製造法およびそれを含む製薬学的組成物 - Google Patents
４α，５α−エポキシ−３，２０−ジオキソプレグナン−２α，１６α−ジカルボニトリル，その製造法およびそれを含む製薬学的組成物Info
- Publication number
- JPS581000A JPS581000A JP57106064A JP10606482A JPS581000A JP S581000 A JPS581000 A JP S581000A JP 57106064 A JP57106064 A JP 57106064A JP 10606482 A JP10606482 A JP 10606482A JP S581000 A JPS581000 A JP S581000A
- Authority
- JP
- Japan
- Prior art keywords
- epoxy
- pregna
- alpha
- carbonitrile
- dicarbonitrile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- 239000011593 sulfur Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 230000036325 urinary excretion Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0057—Nitrogen and oxygen
- C07J71/0063—Nitrogen and oxygen at position 2(3)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/275,294 US4331663A (en) | 1981-06-19 | 1981-06-19 | 4α,5α-Epoxy-3,20-dioxopregnane-2α,16α-dicarbonitrile and intermediates and process for preparation, method of use and compositions thereof |
| US275294 | 1988-11-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS581000A true JPS581000A (ja) | 1983-01-06 |
Family
ID=23051676
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57106064A Pending JPS581000A (ja) | 1981-06-19 | 1982-06-19 | ４α，５α−エポキシ−３，２０−ジオキソプレグナン−２α，１６α−ジカルボニトリル，その製造法およびそれを含む製薬学的組成物 |
Country Status (8)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59221293A (ja) * | 1983-05-26 | 1984-12-12 | 株式会社東京タツノ | 給油装置 |
| US6226505B1 (en) | 1996-11-20 | 2001-05-01 | Nec Corporation | Automatic frequency correction apparatus and method for radio calling system |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4755595A (en) * | 1985-11-01 | 1988-07-05 | Sterling Drug Inc. | Enhanced production of 4,5-unsaturated steroids utilizing methanol solvation |
| GB2375958B (en) * | 2001-04-09 | 2005-03-02 | George Margetts | The use of steroids to lower the levels of cortisol |
| GB2400554B (en) * | 2003-04-16 | 2007-04-18 | George Margetts | Treatment of angiotensin II-induced cardiovascular disease |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2817671A (en) * | 1956-03-20 | 1957-12-24 | Searle & Co | 16-cyano and 16-cyanoalkyl 3, 20-dioxy-genated pregnenes |
| US3135743A (en) * | 1960-06-29 | 1964-06-02 | Sterling Drug Inc | Steroido[2. 3-d]isoxazoles and preparation thereof |
| GB1123770A (en) * | 1966-11-15 | 1968-08-14 | Sterling Drug Inc | 2-cyano-3-oxo-steroids |
| US3296255A (en) * | 1963-11-29 | 1967-01-03 | Sterling Drug Inc | 2-cyano steroids |
| DE2336438C2 (de) * | 1973-07-14 | 1983-07-07 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von 17 β- Oxalylsteroiden |
-
1981
- 1981-06-19 US US06/275,294 patent/US4331663A/en not_active Expired - Fee Related
-
1982
- 1982-05-27 EP EP82104655A patent/EP0072894A1/en not_active Ceased
- 1982-05-28 NZ NZ200779A patent/NZ200779A/en unknown
- 1982-05-28 AU AU84279/82A patent/AU8427982A/en not_active Abandoned
- 1982-06-11 GR GR68414A patent/GR75942B/el unknown
- 1982-06-17 KR KR1019820002696A patent/KR840000582A/ko not_active Withdrawn
- 1982-06-18 DK DK274882A patent/DK274882A/da not_active Application Discontinuation
- 1982-06-19 JP JP57106064A patent/JPS581000A/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59221293A (ja) * | 1983-05-26 | 1984-12-12 | 株式会社東京タツノ | 給油装置 |
| US6226505B1 (en) | 1996-11-20 | 2001-05-01 | Nec Corporation | Automatic frequency correction apparatus and method for radio calling system |
Also Published As
| Publication number | Publication date |
|---|---|
| AU8427982A (en) | 1982-12-23 |
| KR840000582A (ko) | 1984-02-25 |
| US4331663A (en) | 1982-05-25 |
| EP0072894A1 (en) | 1983-03-02 |
| NZ200779A (en) | 1985-04-30 |
| DK274882A (da) | 1982-12-20 |
| GR75942B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-08-02 |
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