JPS5798253A - Naphthalenesulfonamide derivative - Google Patents

Naphthalenesulfonamide derivative

Info

Publication number
JPS5798253A
JPS5798253A JP55173830A JP17383080A JPS5798253A JP S5798253 A JPS5798253 A JP S5798253A JP 55173830 A JP55173830 A JP 55173830A JP 17383080 A JP17383080 A JP 17383080A JP S5798253 A JPS5798253 A JP S5798253A
Authority
JP
Japan
Prior art keywords
compound shown
formula
formulai
give
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP55173830A
Other languages
Japanese (ja)
Inventor
Hiroyoshi Hidaka
Taketoshi Kinoshita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Chemiphar Co Ltd
Original Assignee
Nippon Chemiphar Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co Ltd filed Critical Nippon Chemiphar Co Ltd
Priority to JP55173830A priority Critical patent/JPS5798253A/en
Publication of JPS5798253A publication Critical patent/JPS5798253A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A compound shown by the formulaI(X is halogen; Y is OH, or 1-piperidinyl having a lower alkyl at 4-position; n is 2W6) and its salt.
EXAMPLE: 4-Methyl-1- [ N4-( 5-chloro-1-naphthalenesulfonyl )-homorissyl ]piperidine acetate.
USE: A compound having thrombine activating effect useful for hemostasis.
PROCESS: A compound shown by the formula II with its an α-position protected is reacted with a naphthalenesulfonyl halide derivative shown by the formula III in a solvent (e.g., water, acetone, dioxane, etc.) to be used in the Schotten- Baumann reaction at a temperature under cooling by ice W the boiling point of the solvent, to give a compound shown by the formula IV. The protecting group is removed selectively, to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP55173830A 1980-12-11 1980-12-11 Naphthalenesulfonamide derivative Pending JPS5798253A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55173830A JPS5798253A (en) 1980-12-11 1980-12-11 Naphthalenesulfonamide derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55173830A JPS5798253A (en) 1980-12-11 1980-12-11 Naphthalenesulfonamide derivative

Publications (1)

Publication Number Publication Date
JPS5798253A true JPS5798253A (en) 1982-06-18

Family

ID=15967941

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55173830A Pending JPS5798253A (en) 1980-12-11 1980-12-11 Naphthalenesulfonamide derivative

Country Status (1)

Country Link
JP (1) JPS5798253A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001332A1 (en) * 1993-07-01 1995-01-12 Nkk Corporation Arylsulfonamide derivative and pharmaceutical composition containing the same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001332A1 (en) * 1993-07-01 1995-01-12 Nkk Corporation Arylsulfonamide derivative and pharmaceutical composition containing the same

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