JPS5798253A - Naphthalenesulfonamide derivative - Google Patents
Naphthalenesulfonamide derivativeInfo
- Publication number
- JPS5798253A JPS5798253A JP55173830A JP17383080A JPS5798253A JP S5798253 A JPS5798253 A JP S5798253A JP 55173830 A JP55173830 A JP 55173830A JP 17383080 A JP17383080 A JP 17383080A JP S5798253 A JPS5798253 A JP S5798253A
- Authority
- JP
- Japan
- Prior art keywords
- compound shown
- formula
- formulai
- give
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A compound shown by the formulaI(X is halogen; Y is OH, or 1-piperidinyl having a lower alkyl at 4-position; n is 2W6) and its salt.
EXAMPLE: 4-Methyl-1- [ N4-( 5-chloro-1-naphthalenesulfonyl )-homorissyl ]piperidine acetate.
USE: A compound having thrombine activating effect useful for hemostasis.
PROCESS: A compound shown by the formula II with its an α-position protected is reacted with a naphthalenesulfonyl halide derivative shown by the formula III in a solvent (e.g., water, acetone, dioxane, etc.) to be used in the Schotten- Baumann reaction at a temperature under cooling by ice W the boiling point of the solvent, to give a compound shown by the formula IV. The protecting group is removed selectively, to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55173830A JPS5798253A (en) | 1980-12-11 | 1980-12-11 | Naphthalenesulfonamide derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55173830A JPS5798253A (en) | 1980-12-11 | 1980-12-11 | Naphthalenesulfonamide derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5798253A true JPS5798253A (en) | 1982-06-18 |
Family
ID=15967941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55173830A Pending JPS5798253A (en) | 1980-12-11 | 1980-12-11 | Naphthalenesulfonamide derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5798253A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995001332A1 (en) * | 1993-07-01 | 1995-01-12 | Nkk Corporation | Arylsulfonamide derivative and pharmaceutical composition containing the same |
-
1980
- 1980-12-11 JP JP55173830A patent/JPS5798253A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995001332A1 (en) * | 1993-07-01 | 1995-01-12 | Nkk Corporation | Arylsulfonamide derivative and pharmaceutical composition containing the same |
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