JPS5618947A - 2- 3-carbamoylphenyamino -n- 3,4-dimethoxyphenethyl acetamide trihydrate - Google Patents
2- 3-carbamoylphenyamino -n- 3,4-dimethoxyphenethyl acetamide trihydrateInfo
- Publication number
- JPS5618947A JPS5618947A JP9459779A JP9459779A JPS5618947A JP S5618947 A JPS5618947 A JP S5618947A JP 9459779 A JP9459779 A JP 9459779A JP 9459779 A JP9459779 A JP 9459779A JP S5618947 A JPS5618947 A JP S5618947A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound shown
- hydrate
- reacted
- give
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:The titled compound shown by the formula I.
USE: An ulcer preventive drug. Having central ulcer preventive action.
PROCESS: An amine compound shown by the formula III is reacted with a carboxylic acid shown by the formula IV or its reactive derivative, or a compound shwon by the formula V (Y is halogen) is reacted with an amine compound shown by the formula VI preferably in the presence of a deoxidizer to give an anhydride shown by the formula I or its acid addition salt, which is treated with water in a solvent, e.g., a lower alcohol, stirred for several hours, and allowed to stand so that a hydrate is crystallized. The hydrate is filtered and subjected to air-drying at room temperatures to give a compound shown by the formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9459779A JPS5618947A (en) | 1979-07-25 | 1979-07-25 | 2- 3-carbamoylphenyamino -n- 3,4-dimethoxyphenethyl acetamide trihydrate |
CA000333939A CA1110628A (en) | 1978-08-25 | 1979-08-16 | N-phenethylacetamide compounds and process for preparation thereof |
DK343479A DK149748C (en) | 1978-08-25 | 1979-08-16 | ANALOGY PROCEDURE FOR THE PREPARATION OF N-PHENETHYLACETAMIDE COMPOUNDS |
ES483484A ES483484A1 (en) | 1978-08-25 | 1979-08-20 | N-Phenethylacetamide compounds, processes for their preparation and therapeutic compositions containing them. |
EP79103116A EP0009608B1 (en) | 1978-08-25 | 1979-08-23 | N-phenethylacetamide compounds, processes for their preparation and therapeutic compositions containing them |
DE7979103116T DE2962567D1 (en) | 1978-08-25 | 1979-08-23 | N-phenethylacetamide compounds, processes for their preparation and therapeutic compositions containing them |
AT0570879A AT367397B (en) | 1978-08-25 | 1979-08-24 | METHOD FOR PRODUCING NEW N-PHENAETHYL-GLYCINAMIDES |
US06/070,085 US4297357A (en) | 1978-08-25 | 1979-08-27 | N-Phenethylacetamide compounds and process for preparation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP9459779A JPS5618947A (en) | 1979-07-25 | 1979-07-25 | 2- 3-carbamoylphenyamino -n- 3,4-dimethoxyphenethyl acetamide trihydrate |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5618947A true JPS5618947A (en) | 1981-02-23 |
JPS631938B2 JPS631938B2 (en) | 1988-01-14 |
Family
ID=14114674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP9459779A Granted JPS5618947A (en) | 1978-08-25 | 1979-07-25 | 2- 3-carbamoylphenyamino -n- 3,4-dimethoxyphenethyl acetamide trihydrate |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5618947A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01228948A (en) * | 1988-03-09 | 1989-09-12 | Dai Ichi Seiyaku Co Ltd | Hydroxyphenetylamine derivative |
WO1994025015A1 (en) * | 1993-04-28 | 1994-11-10 | Daiichi Pharmaceutical Co., Ltd. | Digestive symptom ameliorant |
JPH0710748A (en) * | 1993-04-28 | 1995-01-13 | Dai Ichi Seiyaku Co Ltd | Digestive organ symptom-improving agent |
-
1979
- 1979-07-25 JP JP9459779A patent/JPS5618947A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH01228948A (en) * | 1988-03-09 | 1989-09-12 | Dai Ichi Seiyaku Co Ltd | Hydroxyphenetylamine derivative |
WO1994025015A1 (en) * | 1993-04-28 | 1994-11-10 | Daiichi Pharmaceutical Co., Ltd. | Digestive symptom ameliorant |
JPH0710748A (en) * | 1993-04-28 | 1995-01-13 | Dai Ichi Seiyaku Co Ltd | Digestive organ symptom-improving agent |
Also Published As
Publication number | Publication date |
---|---|
JPS631938B2 (en) | 1988-01-14 |
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