JPS567762A - Acylated indole derivative, its preparation, and platelet coagulation inhibiting agent containing the same - Google Patents

Acylated indole derivative, its preparation, and platelet coagulation inhibiting agent containing the same

Info

Publication number
JPS567762A
JPS567762A JP8080279A JP8080279A JPS567762A JP S567762 A JPS567762 A JP S567762A JP 8080279 A JP8080279 A JP 8080279A JP 8080279 A JP8080279 A JP 8080279A JP S567762 A JPS567762 A JP S567762A
Authority
JP
Japan
Prior art keywords
formula
lower alkyl
inhibiting agent
compound
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8080279A
Other languages
Japanese (ja)
Other versions
JPS6233225B2 (en
Inventor
Takeo Oba
Toshio Tanaka
Noriaki Okamura
Kenzo Watanabe
Kiyoshi Sakauchi
Akira Otsu
Tatsuyuki Naritomo
Seiji Kurozumi
Takeshi Yu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP8080279A priority Critical patent/JPS567762A/en
Priority to EP19800302180 priority patent/EP0022634B1/en
Priority to DE8080302180T priority patent/DE3062613D1/en
Publication of JPS567762A publication Critical patent/JPS567762A/en
Publication of JPS6233225B2 publication Critical patent/JPS6233225B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

NEW MATERIAL:The titled compound of formula I (R1 is H, lower alkyl or acyl; R2 is H or lower alkyl; R3,4 are H, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, amino, CF3, OH, etc.; R3 and R4may together form methylenedioxy or ethlenedioxy; phi is aryl or alicyclic group). EXAMPLE:3-Benzoyl-1-(1-methoxy-2-propyl)-2-methylindole. USE:A platelet coagulation inhibiting agent. It is also expected as a compound having an antiinflammatory and fibrinolytic activity. PROCESS:A derivative of tetrahydroacylated indole of formula II (R1' is lower alkyl or acyl) is dehydrogenated to give a compound of formula I (R1 is R1'), or a derivative of tetrahydroacylated indole of formula III (R1'' is acyl) is dehydrogenated and then hydrolyzed to give a compound of formula I (R1 is H).
JP8080279A 1979-06-28 1979-06-28 Acylated indole derivative, its preparation, and platelet coagulation inhibiting agent containing the same Granted JPS567762A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP8080279A JPS567762A (en) 1979-06-28 1979-06-28 Acylated indole derivative, its preparation, and platelet coagulation inhibiting agent containing the same
EP19800302180 EP0022634B1 (en) 1979-06-28 1980-06-27 Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them
DE8080302180T DE3062613D1 (en) 1979-06-28 1980-06-27 Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8080279A JPS567762A (en) 1979-06-28 1979-06-28 Acylated indole derivative, its preparation, and platelet coagulation inhibiting agent containing the same

Publications (2)

Publication Number Publication Date
JPS567762A true JPS567762A (en) 1981-01-27
JPS6233225B2 JPS6233225B2 (en) 1987-07-20

Family

ID=13728588

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8080279A Granted JPS567762A (en) 1979-06-28 1979-06-28 Acylated indole derivative, its preparation, and platelet coagulation inhibiting agent containing the same

Country Status (1)

Country Link
JP (1) JPS567762A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5639068A (en) * 1979-09-05 1981-04-14 Teijin Ltd Acylated indole derivative and blood platelet coagulation inhibitor containing the same as effective component

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102653340B1 (en) * 2023-02-27 2024-04-02 쿠팡 주식회사 Electronic apparatus and method for managing logistics

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5639068A (en) * 1979-09-05 1981-04-14 Teijin Ltd Acylated indole derivative and blood platelet coagulation inhibitor containing the same as effective component

Also Published As

Publication number Publication date
JPS6233225B2 (en) 1987-07-20

Similar Documents

Publication Publication Date Title
JO1351B1 (en) Chemical compounds
JPS56131565A (en) 4-substituted-2-oxoazetidine compound and its preparation
JPS57212150A (en) Diolefin amides, their preparations, insecticides and acaricides containing them
JPS5632474A (en) Piperazine derivative and its preparation
JPS567762A (en) Acylated indole derivative, its preparation, and platelet coagulation inhibiting agent containing the same
JPS54128591A (en) Cephalosporin analog
JPS57118555A (en) Leucotriene-analog compound, its preparation, and leucotriene-biosynthesis inhibiting agent containing said compound as active component
JPS554337A (en) Cephalosporin analogs
JPS55164672A (en) Azetidine derivative and its preparation
JPS55130949A (en) Novel phenylacetamide derivative
JPS5473797A (en) Pyride 3.2.1-jk carbazole derivative
JPS52100473A (en) Novel azimidebenzamide derivative and its production
JPS5359656A (en) Silacyclopropene derivatives and process for preparation of the same
JPS55162758A (en) Novel phenylacetamide derivative
ES8300747A1 (en) Indol acetic derivatives, process for producing the same and pharmaceutical compositions comprising the same.
JPS55129275A (en) Farnesylacetic acid amide bearing piperazine ring or its salt
JPS51118799A (en) Method for preparing pyridindole derivatives
JPS51115918A (en) Germicides for the porposes withowt medical treatment and method for p reparing them
JPS527919A (en) Process for preparation of beta-sulfenylacrylic acid and its salt
JPS52254A (en) Process for preparation of secopenicilanic acid amide derivatives
JPS52156876A (en) Preparation of novel isoquinolone
JPS5686165A (en) Pyrazolidin-3-one derivative and its preparation
JPS5363389A (en) 5-fluorouracil derivs. and process for their preparation
JPS5350184A (en) Novel imides and their preparation
NO160613C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PYRIDAZINO (4,3-C) -ISOKINOLINE DERIVATIVES.