JPS567762A - Acylated indole derivative, its preparation, and platelet coagulation inhibiting agent containing the same - Google Patents
Acylated indole derivative, its preparation, and platelet coagulation inhibiting agent containing the sameInfo
- Publication number
- JPS567762A JPS567762A JP8080279A JP8080279A JPS567762A JP S567762 A JPS567762 A JP S567762A JP 8080279 A JP8080279 A JP 8080279A JP 8080279 A JP8080279 A JP 8080279A JP S567762 A JPS567762 A JP S567762A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- lower alkyl
- inhibiting agent
- compound
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
NEW MATERIAL:The titled compound of formula I (R1 is H, lower alkyl or acyl; R2 is H or lower alkyl; R3,4 are H, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, amino, CF3, OH, etc.; R3 and R4may together form methylenedioxy or ethlenedioxy; phi is aryl or alicyclic group). EXAMPLE:3-Benzoyl-1-(1-methoxy-2-propyl)-2-methylindole. USE:A platelet coagulation inhibiting agent. It is also expected as a compound having an antiinflammatory and fibrinolytic activity. PROCESS:A derivative of tetrahydroacylated indole of formula II (R1' is lower alkyl or acyl) is dehydrogenated to give a compound of formula I (R1 is R1'), or a derivative of tetrahydroacylated indole of formula III (R1'' is acyl) is dehydrogenated and then hydrolyzed to give a compound of formula I (R1 is H).
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8080279A JPS567762A (en) | 1979-06-28 | 1979-06-28 | Acylated indole derivative, its preparation, and platelet coagulation inhibiting agent containing the same |
EP19800302180 EP0022634B1 (en) | 1979-06-28 | 1980-06-27 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them |
DE8080302180T DE3062613D1 (en) | 1979-06-28 | 1980-06-27 | Acylated indole derivatives, processes for their preparation and pharmaceutical compositions and drugs comprising them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8080279A JPS567762A (en) | 1979-06-28 | 1979-06-28 | Acylated indole derivative, its preparation, and platelet coagulation inhibiting agent containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS567762A true JPS567762A (en) | 1981-01-27 |
JPS6233225B2 JPS6233225B2 (en) | 1987-07-20 |
Family
ID=13728588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8080279A Granted JPS567762A (en) | 1979-06-28 | 1979-06-28 | Acylated indole derivative, its preparation, and platelet coagulation inhibiting agent containing the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS567762A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5639068A (en) * | 1979-09-05 | 1981-04-14 | Teijin Ltd | Acylated indole derivative and blood platelet coagulation inhibitor containing the same as effective component |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102653340B1 (en) * | 2023-02-27 | 2024-04-02 | 쿠팡 주식회사 | Electronic apparatus and method for managing logistics |
-
1979
- 1979-06-28 JP JP8080279A patent/JPS567762A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5639068A (en) * | 1979-09-05 | 1981-04-14 | Teijin Ltd | Acylated indole derivative and blood platelet coagulation inhibitor containing the same as effective component |
Also Published As
Publication number | Publication date |
---|---|
JPS6233225B2 (en) | 1987-07-20 |
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