JPS5795977A - Preparation of piperidinophenylpropionic acid - Google Patents

Preparation of piperidinophenylpropionic acid

Info

Publication number
JPS5795977A
JPS5795977A JP55170920A JP17092080A JPS5795977A JP S5795977 A JPS5795977 A JP S5795977A JP 55170920 A JP55170920 A JP 55170920A JP 17092080 A JP17092080 A JP 17092080A JP S5795977 A JPS5795977 A JP S5795977A
Authority
JP
Japan
Prior art keywords
piperidinophenyl
chloro
formula
raw material
metal hydroxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP55170920A
Other languages
Japanese (ja)
Inventor
Kazutaka Arai
Yoshio Obara
Motoo Mutsuto
Shin Yamada
Yasuo Takakuwa
Genichi Dobashi
Katsuyuki Ogura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissan Chemical Corp
Sagami Chemical Research Institute
Original Assignee
Nissan Chemical Corp
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Corp, Sagami Chemical Research Institute filed Critical Nissan Chemical Corp
Priority to JP55170920A priority Critical patent/JPS5795977A/en
Publication of JPS5795977A publication Critical patent/JPS5795977A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To obtain the titled substance useful as an antiphlogistic and analgesic agent by a simple operation in high yield, by using 2-(3-chloro-4-piperidinophenyl) propylidene azanol to be synthesized easily from an inexpensive industrial reagent as a raw material, treating it with an alkali metal hydroxide, etc.
CONSTITUTION: 2-(3-chloro-4-piperidinophenyl)propylidene azanol shown by the formula I as a raw material is treated with preferably 3W5 equivalents of an alkali metal hydroxide or an alkaline earth metal hydroxide in a high-boiling glycol type solvent, e.g., ethylene glycol, etc. at 80W250°C, to give the titled compound. The raw material compound shown by the formula I is easily obtained by treating 2-(3-chloro-4-piperidinophenyl)-2-methyloxysilane shown by the formula II with an acid to give 2-(3-chloro-4-piperidinophenyl)propanal shown by the formula III, which is reacted with hydroxylamine.
COPYRIGHT: (C)1982,JPO&Japio
JP55170920A 1980-12-05 1980-12-05 Preparation of piperidinophenylpropionic acid Pending JPS5795977A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55170920A JPS5795977A (en) 1980-12-05 1980-12-05 Preparation of piperidinophenylpropionic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55170920A JPS5795977A (en) 1980-12-05 1980-12-05 Preparation of piperidinophenylpropionic acid

Publications (1)

Publication Number Publication Date
JPS5795977A true JPS5795977A (en) 1982-06-15

Family

ID=15913796

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55170920A Pending JPS5795977A (en) 1980-12-05 1980-12-05 Preparation of piperidinophenylpropionic acid

Country Status (1)

Country Link
JP (1) JPS5795977A (en)

Similar Documents

Publication Publication Date Title
JPS5690031A (en) Preparation of aromatic aldehyde
JPS5795977A (en) Preparation of piperidinophenylpropionic acid
JPS5695142A (en) Preparation of aliphatic aldehyde
JPS57203053A (en) Preparation of cyanoacetic acid ester
JPS5581818A (en) Method of fluorination
JPS53144503A (en) Preparation of aldehyde
JPS56113745A (en) Preparation of bromonitroalcohol
JPS5668668A (en) Preparation of 2-indolinones
JPS549203A (en) Preparation of alpha-branched aliphatic carboxylic acid
JPS5441869A (en) 1-methylsulfinyl-1-methylthio-2-(n-alkylpyrrolyl-2)- ethylene
JPS55160741A (en) New cyclopentenone compound and its preparation
JPS5626832A (en) Preparation of cyclopentenolone
JPS5711957A (en) Novel aldehyde compound and its preparation
JPS5795985A (en) 2-(3-chloro-4-piperidinophenyl)-2-methyloxirane
JPS5562050A (en) Preparation of substituted phenylacetohydroxamic acid
JPS5414949A (en) Preparation of benzoin ether
JPS57102856A (en) Preparation of oxime compound
JPS55143962A (en) Novel aldehyde compound and its preparation
JPS56156229A (en) Preparation of terephthaldialdehyde monoacetal and its preparation
JPS5522633A (en) Preparation of peroxide
JPS5764690A (en) Preparation of 2,3-dicyan-1,4-dithiaanthraquinone
JPS56100759A (en) Preparation of aziridine-2-carboxylic acid
JPS56166144A (en) Preparation of cyclopentenolone
JPS5634657A (en) Preparation of 2-alkoxy-4,6-di(hydroxycarboxymethyl) phenol
JPS574976A (en) Novel azacrown compound and its application