JPS5786298A - Preparation of s-adenosyl-l-methionine - Google Patents
Preparation of s-adenosyl-l-methionineInfo
- Publication number
- JPS5786298A JPS5786298A JP16279180A JP16279180A JPS5786298A JP S5786298 A JPS5786298 A JP S5786298A JP 16279180 A JP16279180 A JP 16279180A JP 16279180 A JP16279180 A JP 16279180A JP S5786298 A JPS5786298 A JP S5786298A
- Authority
- JP
- Japan
- Prior art keywords
- methionine
- adenosyl
- bacterial cells
- bacteria
- atp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: To produce S-adenosyl-L-methionine, by using treated bacterial cells of bacteria having the ability to synthesize the S-adenosyl-L-methionine from ATP (adenosine triphosphate) and methionine.
CONSTITUTION: Microorganisms to be used are selected from bacteria belonging to the genuses Alcaligenes, Proteus, Agrobacterium, Arthrobacter, Cellulomonas, etc. The bacteria are cultivated by the conventional method, and the bacterial cells are collected by the centrifugation, etc., dried and autolyzed. The treated bacterial cells in an amount of about 10W80mg/ml are then reacted with an aqueous solution containing preferably 10W20mM ATP (adenosine triphophate), preferably 5W20mM methionine and mono- and bivalent cations, and the aimed S-adenosyl-L-methionine is separated from the reaction solution.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16279180A JPS5786298A (en) | 1980-11-19 | 1980-11-19 | Preparation of s-adenosyl-l-methionine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16279180A JPS5786298A (en) | 1980-11-19 | 1980-11-19 | Preparation of s-adenosyl-l-methionine |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5786298A true JPS5786298A (en) | 1982-05-29 |
JPS6314958B2 JPS6314958B2 (en) | 1988-04-02 |
Family
ID=15761269
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16279180A Granted JPS5786298A (en) | 1980-11-19 | 1980-11-19 | Preparation of s-adenosyl-l-methionine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5786298A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6881837B2 (en) | 2001-06-07 | 2005-04-19 | Orchid Chemicals & Pharmaceuticals Ltd. | Chemical synthesis of S-adenosyl-L-methionine with enrichment of (S,S)-isomer |
US7667034B2 (en) | 2004-06-23 | 2010-02-23 | Orchid Chemicals & Pharmaceuticals Limited | Chemical synthesis of S-adenosyl-L-methionine with enrichment of (S,S)-isomer |
-
1980
- 1980-11-19 JP JP16279180A patent/JPS5786298A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6881837B2 (en) | 2001-06-07 | 2005-04-19 | Orchid Chemicals & Pharmaceuticals Ltd. | Chemical synthesis of S-adenosyl-L-methionine with enrichment of (S,S)-isomer |
US7667034B2 (en) | 2004-06-23 | 2010-02-23 | Orchid Chemicals & Pharmaceuticals Limited | Chemical synthesis of S-adenosyl-L-methionine with enrichment of (S,S)-isomer |
Also Published As
Publication number | Publication date |
---|---|
JPS6314958B2 (en) | 1988-04-02 |
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